Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

ChainsTypeFamily Name Domain Identifier Family IdentifierProvenance Source (Version)
BSCOP2B SuperfamilyNuclear receptor ligand-binding domain 8044103 3001442 SCOP2B (2022-06-29)
C [auth A]SCOP2B SuperfamilyNuclear receptor ligand-binding domain 8044103 3001442 SCOP2B (2022-06-29)
D [auth C]SCOP2B SuperfamilyNuclear receptor ligand-binding domain 8044103 3001442 SCOP2B (2022-06-29)
A [auth D]SCOP2B SuperfamilyNuclear receptor ligand-binding domain 8044103 3001442 SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

ChainsFamily NameDomain Identifier ArchitecturePossible HomologyHomologyTopologyFamilyProvenance Source (Version)
BHormone_recep_1e7uj7B1 A: alpha arraysX: Nuclear receptor ligand-binding domain (From Topology)H: Nuclear receptor ligand-binding domain (From Topology)T: Nuclear receptor ligand-binding domainF: Hormone_recep_1ECOD (1.6)
C [auth A]Hormone_recep_1e7uj7A1 A: alpha arraysX: Nuclear receptor ligand-binding domain (From Topology)H: Nuclear receptor ligand-binding domain (From Topology)T: Nuclear receptor ligand-binding domainF: Hormone_recep_1ECOD (1.6)
D [auth C]Hormone_recep_1e7uj7C1 A: alpha arraysX: Nuclear receptor ligand-binding domain (From Topology)H: Nuclear receptor ligand-binding domain (From Topology)T: Nuclear receptor ligand-binding domainF: Hormone_recep_1ECOD (1.6)
A [auth D]Hormone_recep_1e7uj7D1 A: alpha arraysX: Nuclear receptor ligand-binding domain (From Topology)H: Nuclear receptor ligand-binding domain (From Topology)T: Nuclear receptor ligand-binding domainF: Hormone_recep_1ECOD (1.6)

Protein Family Annotation Pfam Database Homepage

ChainsAccessionNameDescriptionCommentsSource
A [auth D],
B,
C [auth A],
D [auth C]
PF00104Ligand-binding domain of nuclear hormone receptor (Hormone_recep)Ligand-binding domain of nuclear hormone receptorThis all helical domain is involved in binding the hormone in these receptors.Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

ChainsPolymerMolecular FunctionBiological ProcessCellular Component
A [auth D],
B,
C [auth A],
D [auth C]
Estrogen receptor

Pharos: Disease Associations Pharos Homepage Annotation

ChainsDrug Target  Associated Disease
A [auth D],
B,
C [auth A],
D [auth C]
PharosP03372