7UJM
Estrogen Receptor Alpha Ligand Binding Domain in Complex with a Methylated Lasofoxifene Derivative That Increases Receptor Resonance Time in the Nucleus of Breast Cancer Cells
Domain Annotation: SCOP2 Classification SCOP2 Database Homepage
Chains | Type | Family Name | Domain Identifier | Family Identifier | Provenance Source (Version) |
---|---|---|---|---|---|
A [auth B] | SCOP2B Superfamily | Nuclear receptor ligand-binding domain | 8044103 | 3001442 | SCOP2B (2022-06-29) |
B [auth A] | SCOP2B Superfamily | Nuclear receptor ligand-binding domain | 8044103 | 3001442 | SCOP2B (2022-06-29) |
C | SCOP2B Superfamily | Nuclear receptor ligand-binding domain | 8044103 | 3001442 | SCOP2B (2022-06-29) |
D | SCOP2B Superfamily | Nuclear receptor ligand-binding domain | 8044103 | 3001442 | SCOP2B (2022-06-29) |
Domain Annotation: ECOD Classification ECOD Database Homepage
Chains | Family Name | Domain Identifier | Architecture | Possible Homology | Homology | Topology | Family | Provenance Source (Version) |
---|---|---|---|---|---|---|---|---|
A [auth B] | Hormone_recep | e7ujmB1 | A: alpha arrays | X: Nuclear receptor ligand-binding domain (From Topology) | H: Nuclear receptor ligand-binding domain (From Topology) | T: Nuclear receptor ligand-binding domain | F: Hormone_recep | ECOD (1.6) |
B [auth A] | Hormone_recep_1 | e7ujmA1 | A: alpha arrays | X: Nuclear receptor ligand-binding domain (From Topology) | H: Nuclear receptor ligand-binding domain (From Topology) | T: Nuclear receptor ligand-binding domain | F: Hormone_recep_1 | ECOD (1.6) |
C | Hormone_recep | e7ujmC1 | A: alpha arrays | X: Nuclear receptor ligand-binding domain (From Topology) | H: Nuclear receptor ligand-binding domain (From Topology) | T: Nuclear receptor ligand-binding domain | F: Hormone_recep | ECOD (1.6) |
D | Hormone_recep_1 | e7ujmD1 | A: alpha arrays | X: Nuclear receptor ligand-binding domain (From Topology) | H: Nuclear receptor ligand-binding domain (From Topology) | T: Nuclear receptor ligand-binding domain | F: Hormone_recep_1 | ECOD (1.6) |
Protein Family Annotation Pfam Database Homepage
Chains | Accession | Name | Description | Comments | Source |
---|---|---|---|---|---|
A [auth B], B [auth A], C, D | PF00104 | Ligand-binding domain of nuclear hormone receptor (Hormone_recep) | Ligand-binding domain of nuclear hormone receptor | This all helical domain is involved in binding the hormone in these receptors. | Domain |