Annotations: 7XRL

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2B Superfamily	Cobalamin (vitamin B12)-dependent enzymes	8043858	3000609	SCOP2B (2022-06-29)
D	SCOP2B Superfamily	Cobalamin (vitamin B12)-dependent enzymes	8043858	3000609	SCOP2B (2022-06-29)
B	SCOP2B Superfamily	B12-dependent dehydatase associated subunit	8044419	3000491	SCOP2B (2022-06-29)
E	SCOP2B Superfamily	B12-dependent dehydatase associated subunit	8044419	3000491	SCOP2B (2022-06-29)
F	SCOP2B Superfamily	Diol dehydratase, gamma subunit	8036835	3001460	SCOP2B (2022-06-29)
C	SCOP2B Superfamily	Diol dehydratase, gamma subunit	8036835	3001460	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	F_UNCLASSIFIED	e7xrlA1	A: a/b barrels	X: TIM beta/alpha-barrel	H: TIM barrels (From Topology)	T: TIM barrels	F: F_UNCLASSIFIED	ECOD (1.6)
D	F_UNCLASSIFIED	e7xrlD1	A: a/b barrels	X: TIM beta/alpha-barrel	H: TIM barrels (From Topology)	T: TIM barrels	F: F_UNCLASSIFIED	ECOD (1.6)
B	F_UNCLASSIFIED	e7xrlB1	A: a/b three-layered sandwiches	X: B12-dependent dehydratase associated subunit (From Topology)	H: B12-dependent dehydratase associated subunit (From Topology)	T: B12-dependent dehydratase associated subunit	F: F_UNCLASSIFIED	ECOD (1.6)
E	F_UNCLASSIFIED	e7xrlE1	A: a/b three-layered sandwiches	X: B12-dependent dehydratase associated subunit (From Topology)	H: B12-dependent dehydratase associated subunit (From Topology)	T: B12-dependent dehydratase associated subunit	F: F_UNCLASSIFIED	ECOD (1.6)
F	F_UNCLASSIFIED	e7xrlF1	A: alpha bundles	X: Diol dehydratase, gamma subunit (From Topology)	H: Diol dehydratase, gamma subunit (From Topology)	T: Diol dehydratase, gamma subunit	F: F_UNCLASSIFIED	ECOD (1.6)
C	F_UNCLASSIFIED	e7xrlC1	A: alpha bundles	X: Diol dehydratase, gamma subunit (From Topology)	H: Diol dehydratase, gamma subunit (From Topology)	T: Diol dehydratase, gamma subunit	F: F_UNCLASSIFIED	ECOD (1.6)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, D	PF02286	Dehydratase large subunit (Dehydratase_LU)	Dehydratase large subunit	This family contains the large subunit of the trimeric diol dehydratases and glycerol dehydratases. These enzymes are produced by some enterobacteria in response to growth substances.	Domain
B, E	PF02288	Dehydratase medium subunit (Dehydratase_MU)	Dehydratase medium subunit	This family contains the medium subunit of the trimeric diol dehydratases and glycerol dehydratases. These enzymes are produced by some enterobacteria in response to growth substances.	Domain
C, F	PF02287	Dehydratase small subunit (Dehydratase_SU)	Dehydratase small subunit	This family contains the small subunit of the trimeric diol dehydratases and glycerol dehydratases. These enzymes are produced by some enterobacteria in response to growth substances.	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, D	Diol dehydrase alpha subunit	vitamin binding binding cobalamin binding organic cyclic compound binding tetrapyrrole binding heterocyclic compound binding small molecule binding hydro-lyase activity lyase activity propanediol dehydratase activity catalytic activity carbon-oxygen lyase activity cation binding ion binding vitamin binding binding cobalamin binding organic cyclic compound binding tetrapyrrole binding heterocyclic compound binding small molecule binding hydro-lyase activity lyase activity propanediol dehydratase activity catalytic activity carbon-oxygen lyase activity cation binding ion binding metal ion binding	-	-
B, E	Diol dehydrase beta subunit	hydro-lyase activity lyase activity propanediol dehydratase activity catalytic activity carbon-oxygen lyase activity	-	-
C, F	Diol dehydrase gamma subunit	hydro-lyase activity lyase activity propanediol dehydratase activity catalytic activity carbon-oxygen lyase activity	-	-

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, D	IPR003206	Diol/glycerol dehydratase, large subunit	Domain
A, D	IPR036999	Diol/glycerol dehydratase, large subunit superfamily	Homologous Superfamily
A, D	IPR016176	Cobalamin (vitamin B12)-dependent enzyme, catalytic	Homologous Superfamily
B, E	IPR025541	Propanediol/glycerol dehydratase, medium subunit	Family
B, E	IPR003208	Diol/glycerol dehydratase/dehydratase reactivating factor	Family
B, E	IPR010254	B12-dependent dehydratases, beta subunit	Homologous Superfamily
C, F	IPR036091	Propanediol/glycerol dehydratase, small subunit superfamily	Homologous Superfamily
C, F	IPR003207	Propanediol/glycerol dehydratase, small subunit	Family

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.