Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

ChainsDomain InfoClassFoldSuperfamilyFamilyDomainSpeciesProvenance Source (Version)
Ad7lapa1 Alpha and beta proteins (a/b) TTHA0583/YokD-like TTHA0583/YokD-like automated matches automated matches (Streptomyces griseus ) [TaxId: 1911 ], SCOPe (2.08)
Ad7lapa2 Artifacts Tags Tags Tags N-terminal Tags (Streptomyces griseus ) [TaxId: 1911 ], SCOPe (2.08)
Bd7lapb1 Alpha and beta proteins (a/b) TTHA0583/YokD-like TTHA0583/YokD-like automated matches automated matches (Streptomyces griseus ) [TaxId: 1911 ], SCOPe (2.08)
Bd7lapb2 Artifacts Tags Tags Tags N-terminal Tags (Streptomyces griseus ) [TaxId: 1911 ], SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

ChainsTypeFamily Name Domain Identifier Family IdentifierProvenance Source (Version)
ASCOP2 FamilyAminoglycoside 3-N-acetyltransferase-like 8102466 4002431 SCOP2 (2022-06-29)
ASCOP2 SuperfamilyTTHA0583/YokD-like 8102467 3001081 SCOP2 (2022-06-29)
BSCOP2B SuperfamilyTTHA0583/YokD-like 8102467 3001081 SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

ChainsFamily NameDomain Identifier ArchitecturePossible HomologyHomologyTopologyFamilyProvenance Source (Version)
AAntibiotic_NATe7lapA1 A: a/b three-layered sandwichesX: Hypothetical protein TT1679 (From Topology)H: Hypothetical protein TT1679 (From Topology)T: Hypothetical protein TT1679F: Antibiotic_NATECOD (1.6)
BAntibiotic_NATe7lapB1 A: a/b three-layered sandwichesX: Hypothetical protein TT1679 (From Topology)H: Hypothetical protein TT1679 (From Topology)T: Hypothetical protein TT1679F: Antibiotic_NATECOD (1.6)

AMR Gene: CARD Annotation CARD Database Homepage

ChainsAccessionShort NameDescriptionProvenance Source (Version)
A, B
ARO:3002544AAC(3)-XaAAC(3)-Xa is a chromosomal-encoded aminoglycoside acetyltransferase in Streptomyces griseus.CARD (3.3.0)

AMR Gene Family: CARD Annotation CARD Database Homepage

ChainsAccessionGene FamilyDrug Class Resistance MachanismProvenance Source (Version)
A, B
ARO:3000322AAC(3)aminoglycoside antibioticantibiotic inactivationCARD (3.3.0)

Protein Family Annotation Pfam Database Homepage

ChainsAccessionNameDescriptionCommentsSource
A, B
PF02522Aminoglycoside 3-N-acetyltransferase (Antibiotic_NAT)Aminoglycoside 3-N-acetyltransferaseThis family consists of bacterial aminoglycoside 3-N-acetyltransferases EC:2.3.1.81, these catalyse the reaction: Acetyl-Co + a 2-deoxystreptamine antibiotic <=> CoA + N3'-acetyl-2-deoxystreptamine antibiotic. The enzyme can use ...This family consists of bacterial aminoglycoside 3-N-acetyltransferases EC:2.3.1.81, these catalyse the reaction: Acetyl-Co + a 2-deoxystreptamine antibiotic <=> CoA + N3'-acetyl-2-deoxystreptamine antibiotic. The enzyme can use a range of antibiotics with 2-deoxystreptamine rings as acceptor for its acetyltransferase activity, this inactivates and confers resistance to gentamicin, kanamycin, tobramycin, neomycin and apramycin amongst others.
Domain

InterPro: Protein Family Classification InterPro Database Homepage