Domain Annotation: ECOD Classification ECOD Database Homepage

ChainsFamily NameDomain Identifier ArchitecturePossible HomologyHomologyTopologyFamilyProvenance Source (Version)
AAntibiotic_NATe7mqmA1 A: a/b three-layered sandwichesX: Hypothetical protein TT1679 (From Topology)H: Hypothetical protein TT1679 (From Topology)T: Hypothetical protein TT1679F: Antibiotic_NATECOD (1.6)
BAntibiotic_NATe7mqmB1 A: a/b three-layered sandwichesX: Hypothetical protein TT1679 (From Topology)H: Hypothetical protein TT1679 (From Topology)T: Hypothetical protein TT1679F: Antibiotic_NATECOD (1.6)
CAntibiotic_NATe7mqmC1 A: a/b three-layered sandwichesX: Hypothetical protein TT1679 (From Topology)H: Hypothetical protein TT1679 (From Topology)T: Hypothetical protein TT1679F: Antibiotic_NATECOD (1.6)
DAntibiotic_NATe7mqmD1 A: a/b three-layered sandwichesX: Hypothetical protein TT1679 (From Topology)H: Hypothetical protein TT1679 (From Topology)T: Hypothetical protein TT1679F: Antibiotic_NATECOD (1.6)

AMR Gene: CARD Annotation CARD Database Homepage

ChainsAccessionShort NameDescriptionProvenance Source (Version)
A, B, C, D
ARO:3002536AAC(3)-IIIaAAC(3)-IIIa is a chromosomal-encoded aminoglycoside acetyltransferase in P. aeruginosa.CARD (3.3.0)

AMR Gene Family: CARD Annotation CARD Database Homepage

ChainsAccessionGene FamilyDrug Class Resistance MachanismProvenance Source (Version)
A, B, C, D
ARO:3000322AAC(3)aminoglycoside antibioticantibiotic inactivationCARD (3.3.0)

Protein Family Annotation Pfam Database Homepage

ChainsAccessionNameDescriptionCommentsSource
A, B, C, D
PF02522Aminoglycoside 3-N-acetyltransferase (Antibiotic_NAT)Aminoglycoside 3-N-acetyltransferaseThis family consists of bacterial aminoglycoside 3-N-acetyltransferases EC:2.3.1.81, these catalyse the reaction: Acetyl-Co + a 2-deoxystreptamine antibiotic <=> CoA + N3'-acetyl-2-deoxystreptamine antibiotic. The enzyme can use ...This family consists of bacterial aminoglycoside 3-N-acetyltransferases EC:2.3.1.81, these catalyse the reaction: Acetyl-Co + a 2-deoxystreptamine antibiotic <=> CoA + N3'-acetyl-2-deoxystreptamine antibiotic. The enzyme can use a range of antibiotics with 2-deoxystreptamine rings as acceptor for its acetyltransferase activity, this inactivates and confers resistance to gentamicin, kanamycin, tobramycin, neomycin and apramycin amongst others.
Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

ChainsPolymerMolecular FunctionBiological ProcessCellular Component
A, B, C, D
Aminoglycoside N(3)-acetyltransferase III -

InterPro: Protein Family Classification InterPro Database Homepage

Protein Modification Annotation

Modified Residue(s)
ChainResidue(s)Description
A, B, C, D
CSO Parent Component: CYS

RESIDAA0205

PSI-MOD :  L-cysteine sulfenic acid MOD:00210