Annotations: 7VE0

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	Asp_C,Asp_N	e7ve0A1	A: beta barrels	X: cradle loop barrel	H: RIFT-related	T: acid protease	F: Asp_C,Asp_N	ECOD (1.6)
B	Asp_C,Asp_N	e7ve0B1	A: beta barrels	X: cradle loop barrel	H: RIFT-related	T: acid protease	F: Asp_C,Asp_N	ECOD (1.6)

Chains	Accession	Name	Description	Comments	Source
A, B	PF00026	Eukaryotic aspartyl protease (Asp)	Eukaryotic aspartyl protease	-	Family

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B	Plasmepsin II	aspartic-type peptidase activity peptidase activity catalytic activity, acting on a protein hydrolase activity aspartic-type endopeptidase activity catalytic activity endopeptidase activity	catabolic process metabolic process cellular process primary metabolic process protein catabolic process protein metabolic process macromolecule metabolic process macromolecule catabolic process hemoglobin metabolic process hemoglobin catabolic process proteolysis	cell periphery cellular anatomical structure plasma membrane membrane cytostome vacuolar membrane membrane-bounded organelle intracellular anatomical structure vacuole intracellular membrane-bounded organelle intracellular organelle bounding membrane of organelle organelle cytoplasm cell periphery cellular anatomical structure plasma membrane membrane cytostome vacuolar membrane membrane-bounded organelle intracellular anatomical structure vacuole intracellular membrane-bounded organelle intracellular organelle bounding membrane of organelle organelle cytoplasm organelle membrane phagolysosome lytic vacuole intracellular vesicle phagocytic vesicle food vacuole cytoplasmic vesicle secondary lysosome vesicle endocytic vesicle lysosome membrane-enclosed lumen vacuolar lumen intracellular organelle lumen organelle lumen

Chains	Accession	Name	Type
A, B	IPR001461	Aspartic peptidase A1	Family
A, B	IPR033121	Peptidase family A1 domain	Domain
A, B	IPR034164	Pepsin-like domain	Domain
A, B	IPR021109	Aspartic peptidase domain superfamily	Homologous Superfamily
A, B	IPR001969	Aspartic peptidase, active site	Active Site