8BEM
STE20-like serine/threonine-protein kinase (SLK) in complex with Tivozanib
Domain Annotation: SCOP2 Classification SCOP2 Database Homepage
Chains | Type | Family Name | Domain Identifier | Family Identifier | Provenance Source (Version) |
---|---|---|---|---|---|
A | SCOP2B Superfamily | Protein kinase-like (PK-like) | 8034645 | 3000066 | SCOP2B (2022-06-29) |
B | SCOP2B Superfamily | Protein kinase-like (PK-like) | 8034645 | 3000066 | SCOP2B (2022-06-29) |
C [auth D] | SCOP2B Superfamily | Protein kinase-like (PK-like) | 8034645 | 3000066 | SCOP2B (2022-06-29) |
D [auth G] | SCOP2B Superfamily | Protein kinase-like (PK-like) | 8034645 | 3000066 | SCOP2B (2022-06-29) |
Domain Annotation: ECOD Classification ECOD Database Homepage
Chains | Family Name | Domain Identifier | Architecture | Possible Homology | Homology | Topology | Family | Provenance Source (Version) |
---|---|---|---|---|---|---|---|---|
A | Pkinase_Tyr | e8bemA1 | A: a+b complex topology | X: Protein kinase/SAICAR synthase/ATP-grasp (From Homology) | H: Protein kinase/SAICAR synthase/ATP-grasp | T: Protein kinase | F: Pkinase_Tyr | ECOD (1.6) |
B | Pkinase_Tyr | e8bemB1 | A: a+b complex topology | X: Protein kinase/SAICAR synthase/ATP-grasp (From Homology) | H: Protein kinase/SAICAR synthase/ATP-grasp | T: Protein kinase | F: Pkinase_Tyr | ECOD (1.6) |
C [auth D] | Pkinase_Tyr | e8bemD1 | A: a+b complex topology | X: Protein kinase/SAICAR synthase/ATP-grasp (From Homology) | H: Protein kinase/SAICAR synthase/ATP-grasp | T: Protein kinase | F: Pkinase_Tyr | ECOD (1.6) |
D [auth G] | Pkinase_Tyr | e8bemG1 | A: a+b complex topology | X: Protein kinase/SAICAR synthase/ATP-grasp (From Homology) | H: Protein kinase/SAICAR synthase/ATP-grasp | T: Protein kinase | F: Pkinase_Tyr | ECOD (1.6) |
Protein Family Annotation Pfam Database Homepage
Chains | Accession | Name | Description | Comments | Source |
---|---|---|---|---|---|
A, B, C [auth D], D [auth G] | PF00069 | Protein kinase domain (Pkinase) | Protein kinase domain | - | Domain |
Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage
InterPro: Protein Family Classification InterPro Database Homepage
Chains | Accession | Name | Type |
---|---|---|---|
A, B, C [auth D], D [auth G] | IPR017441 | Protein kinase, ATP binding site | Binding Site |
A, B, C [auth D], D [auth G] | IPR022165 | Polo kinase kinase | Family |
A, B, C [auth D], D [auth G] | IPR011009 | Protein kinase-like domain superfamily | Homologous Superfamily |
A, B, C [auth D], D [auth G] | IPR000719 | Protein kinase domain | Domain |
A, B, C [auth D], D [auth G] | IPR001943 | UVR domain | Domain |
A, B, C [auth D], D [auth G] | IPR051585 | STE20 Subfamily Serine/Threonine Kinases | Family |
A, B, C [auth D], D [auth G] | IPR008271 | Serine/threonine-protein kinase, active site | Active Site |