Annotations: 8BEO

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B, C, D, E A, B, C, D, E, F	PF00205	Thiamine pyrophosphate enzyme, central domain (TPP_enzyme_M)	Thiamine pyrophosphate enzyme, central domain	The central domain of TPP enzymes contains a 2-fold Rossman fold.	Domain
A, B, C, D, E A, B, C, D, E, F	PF02775	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain (TPP_enzyme_C)	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain	-	Domain
A, B, C, D, E A, B, C, D, E, F	PF02776	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain (TPP_enzyme_N)	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain	-	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B, C, D, E A, B, C, D, E, F	Glyoxylate carboligase	cation binding magnesium ion binding ion binding binding metal ion binding small molecule binding FAD binding flavin adenine dinucleotide binding nucleoside phosphate binding organic cyclic compound binding anion binding nucleotide binding heterocyclic compound binding tartronate-semialdehyde synthase activity cation binding magnesium ion binding ion binding binding metal ion binding small molecule binding FAD binding flavin adenine dinucleotide binding nucleoside phosphate binding organic cyclic compound binding anion binding nucleotide binding heterocyclic compound binding tartronate-semialdehyde synthase activity carboxy-lyase activity lyase activity catalytic activity carbon-carbon lyase activity vitamin binding thiamine pyrophosphate binding quaternary ammonium group binding sulfur compound binding identical protein binding protein binding	alcohol catabolic process catabolic process primary alcohol catabolic process oxoacid metabolic process organic hydroxy compound metabolic process cellular metabolic process glycolate catabolic process carboxylic acid metabolic process alcohol metabolic process organic acid metabolic process organic acid catabolic process cellular catabolic process monocarboxylic acid catabolic process organic hydroxy compound catabolic process carboxylic acid catabolic process alcohol catabolic process catabolic process primary alcohol catabolic process oxoacid metabolic process organic hydroxy compound metabolic process cellular metabolic process glycolate catabolic process carboxylic acid metabolic process alcohol metabolic process organic acid metabolic process organic acid catabolic process cellular catabolic process monocarboxylic acid catabolic process organic hydroxy compound catabolic process carboxylic acid catabolic process metabolic process small molecule metabolic process cellular process monocarboxylic acid metabolic process small molecule catabolic process primary alcohol metabolic process glycolate metabolic process small molecule biosynthetic process cellular biosynthetic process amino acid metabolic process primary metabolic process organic acid biosynthetic process alpha-amino acid metabolic process carboxylic acid biosynthetic process amino acid biosynthetic process biosynthetic process isoleucine biosynthetic process branched-chain amino acid biosynthetic process branched-chain amino acid metabolic process isoleucine metabolic process alpha-amino acid biosynthetic process glyoxylate metabolic process glyoxylate catabolic process cellular aldehyde metabolic process aldehyde catabolic process pyruvate family amino acid metabolic process pyruvate family amino acid biosynthetic process L-amino acid biosynthetic process L-valine biosynthetic process L-amino acid metabolic process proteinogenic amino acid metabolic process proteinogenic amino acid biosynthetic process valine metabolic process	protein-containing complex intracellular anatomical structure catalytic complex acetolactate synthase complex transferase complex cytoplasm cellular anatomical entity

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B, C, D, E A, B, C, D, E, F	IPR045229	Thiamine pyrophosphate enzyme	Family
A, B, C, D, E A, B, C, D, E, F	IPR012001	Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain	Domain
A, B, C, D, E A, B, C, D, E, F	IPR006397	Glyoxylate carboligase	Family
A, B, C, D, E A, B, C, D, E, F	IPR012000	Thiamine pyrophosphate enzyme, central domain	Domain
A, B, C, D, E A, B, C, D, E, F	IPR029061	Thiamin diphosphate-binding fold	Homologous Superfamily
A, B, C, D, E A, B, C, D, E, F	IPR047034	Glyoxylate carboligase, TPP-binding domain	Domain
A, B, C, D, E A, B, C, D, E, F	IPR029035	DHS-like NAD/FAD-binding domain superfamily	Homologous Superfamily
A, B, C, D, E A, B, C, D, E, F	IPR011766	Thiamine pyrophosphate enzyme, TPP-binding	Domain

Protein Modification Annotation

Modified Residue(s)
Chain	Residue(s)	Description
A, B, C, D, E A, B, C, D, E, F	CSO	Parent Component: CYS RESID: AA0205 PSI-MOD : L-cysteine sulfenic acid MOD:00210

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.