8PQQ

Nucleoside 2'deoxyribosyltransferase from Chroococcidiopsis thermalis PCC 7203 E88Q Mutant bound to Clofarabine

External Resource: Annotation

Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B, D	PF05014	Nucleoside 2-deoxyribosyltransferase (Nuc_deoxyrib_tr)	Nucleoside 2-deoxyribosyltransferase	Nucleoside 2-deoxyribosyltransferase EC:2.4.2.6 catalyses the cleavage of the glycosidic bonds of 2`-deoxyribonucleosides [1].	Domain
C	PF05014	Nucleoside 2-deoxyribosyltransferase (Nuc_deoxyrib_tr)	Nucleoside 2-deoxyribosyltransferase	Nucleoside 2-deoxyribosyltransferase EC:2.4.2.6 catalyses the cleavage of the glycosidic bonds of 2`-deoxyribonucleosides [1].	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B, D	Nucleoside 2-deoxyribosyltransferase	cation binding ion binding binding metal ion binding small molecule binding transferase activity catalytic activity hydrolase activity, acting on glycosyl bonds hydrolase activity deoxyribonucleoside 5'-monophosphate N-glycosidase activity hydrolase activity, hydrolyzing N-glycosyl compounds	nucleoside phosphate metabolic process deoxyribonucleoside monophosphate catabolic process nucleoside monophosphate catabolic process catabolic process organophosphate catabolic process primary metabolic process nucleoside phosphate catabolic process deoxyribonucleoside monophosphate metabolic process nucleobase-containing compound catabolic process nucleobase-containing compound metabolic process organophosphate metabolic process nucleobase-containing small molecule metabolic process phosphate-containing compound metabolic process metabolic process nucleoside phosphate metabolic process deoxyribonucleoside monophosphate catabolic process nucleoside monophosphate catabolic process catabolic process organophosphate catabolic process primary metabolic process nucleoside phosphate catabolic process deoxyribonucleoside monophosphate metabolic process nucleobase-containing compound catabolic process nucleobase-containing compound metabolic process organophosphate metabolic process nucleobase-containing small molecule metabolic process phosphate-containing compound metabolic process metabolic process cellular process small molecule metabolic process nucleoside monophosphate metabolic process phosphorus metabolic process	-
C	Nucleoside 2-deoxyribosyltransferase	cation binding ion binding binding metal ion binding small molecule binding transferase activity catalytic activity hydrolase activity, acting on glycosyl bonds hydrolase activity deoxyribonucleoside 5'-monophosphate N-glycosidase activity hydrolase activity, hydrolyzing N-glycosyl compounds	nucleoside phosphate metabolic process deoxyribonucleoside monophosphate catabolic process nucleoside monophosphate catabolic process catabolic process organophosphate catabolic process primary metabolic process nucleoside phosphate catabolic process deoxyribonucleoside monophosphate metabolic process nucleobase-containing compound catabolic process nucleobase-containing compound metabolic process organophosphate metabolic process nucleobase-containing small molecule metabolic process phosphate-containing compound metabolic process metabolic process nucleoside phosphate metabolic process deoxyribonucleoside monophosphate catabolic process nucleoside monophosphate catabolic process catabolic process organophosphate catabolic process primary metabolic process nucleoside phosphate catabolic process deoxyribonucleoside monophosphate metabolic process nucleobase-containing compound catabolic process nucleobase-containing compound metabolic process organophosphate metabolic process nucleobase-containing small molecule metabolic process phosphate-containing compound metabolic process metabolic process cellular process small molecule metabolic process nucleoside monophosphate metabolic process phosphorus metabolic process	-

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B, D	IPR007710	Nucleoside 2-deoxyribosyltransferase	Family
A, B, D	IPR051239	2'-Deoxynucleoside 5'-phosphate N-hydrolase	Family
C	IPR007710	Nucleoside 2-deoxyribosyltransferase	Family
C	IPR051239	2'-Deoxynucleoside 5'-phosphate N-hydrolase	Family

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.