8SI0
Structure of binary complex of human cGAS and bound cGAMP
Domain Annotation: SCOP2 Classification SCOP2 Database Homepage
Protein Family Annotation Pfam Database Homepage
Chains | Accession | Name | Description | Comments | Source |
---|---|---|---|---|---|
PF20266 | Mab-21 protein HhH/H2TH-like domain (Mab-21_C) | Mab-21 protein HhH/H2TH-like domain | This family contains Mab-21 and Mab-21 like proteins. In C. elegans these proteins are required for several aspects of embryonic development [2-3]. | Domain |
Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage
InterPro: Protein Family Classification InterPro Database Homepage
Chains | Accession | Name | Type |
---|---|---|---|
IPR024810 | MAB21L/Cyclic GMP-AMP synthase-like receptor | Family | |
IPR046906 | Mab-21-like, HhH/H2TH-like domain | Domain | |
IPR046903 | Mab-21-like, nucleotidyltransferase domain | Domain |
Pharos: Disease Associations Pharos Homepage Annotation
Chains | Drug Target   | Associated Disease |
---|---|---|
Q8N884 | :