Annotations: 9BT4

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
C, D	PF02775	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain (TPP_enzyme_C)	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain	-	Domain
A [auth B], B [auth A]	PF01855	Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg (POR_N)	Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg	-	Family
A [auth B], B [auth A]	PF17147	Pyruvate:ferredoxin oxidoreductase core domain II (PFOR_II)	Pyruvate:ferredoxin oxidoreductase core domain II	PFOR_II is a core domain of the anaerobic enzyme pyruvate:ferredoxin oxidoreductase and is necessary for inter subunit contacts in conjunction with domains I and IV [1,2].	Domain
E [auth G], F [auth H]	PF00037	4Fe-4S binding domain (Fer4)	4Fe-4S binding domain	Superfamily includes proteins containing domains which bind to iron-sulfur clusters. Members include bacterial ferredoxins, various dehydrogenases, and various reductases. Structure of the domain is an alpha-antiparallel beta sandwich.	Domain
G [auth E], H [auth F]	PF01558	Pyruvate ferredoxin/flavodoxin oxidoreductase (POR)	Pyruvate ferredoxin/flavodoxin oxidoreductase	-	Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
C, D	Pyruvate:Ferredoxin Oxidoreductase, subunit beta	oxidoreductase activity catalytic activity binding cation binding vitamin binding thiamine pyrophosphate binding ion binding organic cyclic compound binding anion binding quaternary ammonium group binding heterocyclic compound binding small molecule binding sulfur compound binding	sulfur compound biosynthetic process biosynthetic process sulfur compound metabolic process metabolic process cellular process small molecule metabolic process organic acid metabolic process	-
A [auth B], B [auth A]	Pyruvate:Ferredoxin Oxidoreductase, subunit alpha	oxidoreductase activity catalytic activity	response to oxidative stress response to stimulus response to stress sulfur compound biosynthetic process biosynthetic process sulfur compound metabolic process metabolic process cellular process small molecule metabolic process organic acid metabolic process	-
E [auth G], F [auth H]	Pyruvate:Ferredoxin Oxidoreductase, subunit delta	oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor oxidoreductase activity oxidoreductase activity, acting on the aldehyde or oxo group of donors catalytic activity iron-sulfur cluster binding binding 4 iron, 4 sulfur cluster binding metal cluster binding small molecule binding cation binding ion binding metal ion binding	-	-
G [auth E], H [auth F]	Pyruvate:Ferredoxin Oxidoreductase, subunit gamma	oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor oxidoreductase activity oxidoreductase activity, acting on the aldehyde or oxo group of donors catalytic activity	-	-

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
C, D	IPR051479	Pyruvate synthase subunit PorB-like	Family
C, D	IPR029061	Thiamin diphosphate-binding fold	Homologous Superfamily
C, D	IPR011766	Thiamine pyrophosphate enzyme, TPP-binding	Domain
A [auth B], B [auth A]	IPR033412	Pyruvate:ferredoxin oxidoreductase, core domain II	Domain
A [auth B], B [auth A]	IPR029061	Thiamin diphosphate-binding fold	Homologous Superfamily
A [auth B], B [auth A]	IPR009014	Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II	Homologous Superfamily
A [auth B], B [auth A]	IPR002880	Pyruvate flavodoxin/ferredoxin oxidoreductase, pyrimidine binding domain	Domain
A [auth B], B [auth A]	IPR050722	Pyruvate:ferredoxin/flavodoxin oxidoreductase	Family
A [auth B], B [auth A]	IPR053390	Pyruvate Synthase Subunit PorA	Family
E [auth G], F [auth H]	IPR017900	4Fe-4S ferredoxin, iron-sulphur binding, conserved site	Conserved Site
E [auth G], F [auth H]	IPR053389	Pyruvate Synthase Subunit PorD	Family
E [auth G], F [auth H]	IPR017896	4Fe-4S ferredoxin-type, iron-sulphur binding domain	Domain
E [auth G], F [auth H]	IPR011898	2-oxoacid:acceptor oxidoreductase, delta subunit, pyruvate/2-ketoisovalerate	Family
G [auth E], H [auth F]	IPR002869	Pyruvate-flavodoxin oxidoreductase, central domain	Homologous Superfamily
G [auth E], H [auth F]	IPR011894	2-oxoacid:acceptor oxidoreductase, gamma subunit, pyruvate/2-ketoisovalerate	Domain
G [auth E], H [auth F]	IPR053412	Pyruvate Synthase Subunit PorC	Family
G [auth E], H [auth F]	IPR019752	Pyruvate/ketoisovalerate oxidoreductase, catalytic domain	Domain
G [auth E], H [auth F]	IPR051626	Pyruvate/Ketoisovalerate Oxidoreductase Gamma Subunit	Family

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.