Cyclic dipyrimidine nucleotide synthase CdnE

UniProtKB accession:  P0DSP3

Grouped By:  Matching UniProtKB accession

UniProtKB description:  Cyclic nucleotide synthase (second messenger synthase) of a CBASS antivirus system (PubMed:30787435). CBASS (cyclic oligonucleotide-based antiphage signaling system) provides immunity against bacteriophage. The CD-NTase protein synthesizes cyclic nucleotides in response to infection; these serve as specific second messenger signals. The signals activate a diverse range of effectors, leading to bacterial cell death and thus abortive phage infection (Probable). A type I-B(UU) CBASS system (PubMed:32839535).