Anti-CBASS protein 2
UniProtKB accession: P13314
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Go to UniProtKB: P13314
UniProtKB description: Antagonizes CBASS (cyclic oligonucleotide-based antiphage signaling system) (Probable) (PubMed:36848932). Binds and sequesters host-produced 3',3'-cyclic GMP-AMP (cGAMP) with a dissociation constant of about 30 nM; each homohexamer binds 3 cGAMP molecules with 1 cGAMP molecule binding to 2 monomers (PubMed:36848932). Sequestration of cGAMP inhibits the cGAMP-activated phospholipase activity of host CBASS effector protein CapV (PubMed:36848932).
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