Glutamate decarboxylase alpha

UniProtKB accession:  P69908

Grouped By:  Matching UniProtKB accession

UniProtKB description:  Converts glutamate to gamma-aminobutyrate (GABA), consuming one intracellular proton in the reaction. The gad system helps to maintain a near-neutral intracellular pH when cells are exposed to extremely acidic conditions. The ability to survive transit through the acidic conditions of the stomach is essential for successful colonization of the mammalian host by commensal and pathogenic bacteria.