Isocitrate/homoisocitrate dehydrogenase
UniProtKB accession: Q72IW9
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Go to UniProtKB: Q72IW9
UniProtKB description: Catalyzes the NAD(+)-dependent oxidative decarboxylation of homoisocitrate to 2-oxoadipate (alpha-ketoadipate), a reaction involved in lysine biosynthesis through the alpha-aminoadipate pathway. In addition, has high activity with isocitrate, but is inactive with 3-isopropylmalate.
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