Cohesin subunit SA-1

UniProtKB accession:  Q8WVM7

Grouped By:  Matching UniProtKB accession

UniProtKB description:  Component of cohesin complex, a complex required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. The cohesin complex may also play a role in spindle pole assembly during mitosis.