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HTH-type transcriptional repressor DasR

UniProtKB accession:  Q9K492
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Go to UniProtKB:  Q9K492
UniProtKB description:  Global regulator that is part of the nutrient-sensing system. In the absence of glucosamine 6-P (GlcN6P), represses the phosphotransferase system (PTS) specific for the uptake of N-acetylglucosamine (PTSNag), and genes involved in the metabolism of chitin, as well as several genes involved in development, thereby linking carbon availability to morphogenesis (PubMed:15247334, PubMed:16925557). Also regulates the expression of the ABC transporters DasABC and NgcEFG, which are involved in N,N'-diacetylchitobiose ((GlcNAc)2) uptake (PubMed:17351098, PubMed:30089751). Binds to the DNA consensus sequence 5'-ACTGGTCTAGACCACT-3' (PubMed:15247334, PubMed:16925557).
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