Suppressor of tumorigenicity 14 protein
UniProtKB accession: Q9Y5Y6
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Go to UniProtKB: Q9Y5Y6
UniProtKB description: Exhibits trypsin-like activity as defined by cleavage of synthetic substrates with Arg or Lys as the P1 site (PubMed:10373424). Involved in the terminal differentiation of keratinocytes through prostasin (PRSS8) activation and filaggrin (FLG) processing (PubMed:18843291). Proteolytically cleaves and therefore activates TMPRSS13 (PubMed:28710277).
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