Chemical Component Summary

NameD-NORLEUCINE
Identifiers(2~{R})-2-azanylhexanoic acid
FormulaC6 H13 N O2
Molecular Weight131.173
TypeD-PEPTIDE LINKING
Isomeric SMILESCCCC[C@H](C(=O)O)N
InChIInChI=1S/C6H13NO2/c1-2-3-4-5(7)6(8)9/h5H,2-4,7H2,1H3,(H,8,9)/t5-/m1/s1
InChIKeyLRQKBLKVPFOOQJ-RXMQYKEDSA-N

Chemical Details

Formal Charge0
Atom Count22
Chiral Atom Count1
Bond Count21
Aromatic Bond Count0

Drug Info: DrugBank

DrugBank IDDB04419 
NameD-norleucine
Groups experimental
DescriptionAn unnatural amino acid that is used experimentally to study protein structure and function. It is structurally similar to METHIONINE, however it does not contain SULFUR.
Synonyms
  • D-2-aminohexanoic acid
  • D-(−)-norleucine
  • D-norleucine
CAS number327-56-0

Drug Targets

NameTarget SequencePharmacological ActionActions
Phenylalanine-4-hydroxylaseMSTAVLENPGLGRKLSDFGQETSYIEDNCNQNGAISLIFSLKEEVGALAK...unknown
Parathyroid hormoneMIPAKDMAKVMIVMLAICFLTKSDGKSVKKRSVSEIQLMHNLGKHLNSME...unknown
Hepatocyte nuclear factor 1-alphaMVSKLSQLQTELLAALLESGLSKEALIQALGEPGPYLLAGEGPLDKGESC...unknown
Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS. Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682

Related Resource References

Resource NameReference
PubChem 6999776, 456468
ChEBI CHEBI:143080, CHEBI:42101
CCDC/CSD DLNLIT, GOLVOS, GOLVIM01, GOLVIM02, GOLVUY, GOLWAF, GOLVIM, FITLEZ, GOLVIM03, DLNLUA03, ZATPIX, ZATNUH
COD 4509815, 4509813