M7G

7N-METHYL-8-HYDROGUANOSINE-5'-DIPHOSPHATE



Chemical Component Summary

Name7N-METHYL-8-HYDROGUANOSINE-5'-DIPHOSPHATE
Identifiers[(2~{R},3~{S},4~{R},5~{R})-5-(2-azanyl-7-methyl-6-oxidanylidene-1~{H}-purin-7-ium-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methyl phosphono hydrogen phosphate
FormulaC11 H18 N5 O11 P2
Molecular Weight458.235
TypeNON-POLYMER
Isomeric SMILESC[n+]1cn(c2c1C(=O)NC(=N2)N)[C@H]3[C@@H]([C@@H]([C@H](O3)CO[P@](=O)(O)OP(=O)(O)O)O)O
InChIInChI=1S/C11H17N5O11P2/c1-15-3-16(8-5(15)9(19)14-11(12)13-8)10-7(18)6(17)4(26-10)2-25-29(23,24)27-28(20,21)22/h3-4,6-7,10,17-18H,2H2,1H3,(H5-,12,13,14,19,20,21,22,23,24)/p+1/t4-,6-,7-,10-/m1/s1
InChIKeySBASPRRECYVBRF-KQYNXXCUSA-O

Chemical Details

Formal Charge1
Atom Count47
Chiral Atom Count4
Bond Count49
Aromatic Bond Count5

Drug Info: DrugBank

DrugBank IDDB01960 
Name7-methyl-7,8-dihydroguanosine-5'-diphosphate
Groups experimental
Synonyms7-methyl-7,8-dihydroguanosine-5'-diphosphate
CAS number104809-16-7

Drug Targets

NameTarget SequencePharmacological ActionActions
m7GpppX diphosphataseMADAAPQLGKRKRELDVEEAHAASTEEKEAGVGNGTCAPVRLPFSGFRLQ...unknown
Cap-specific mRNA (nucleoside-2'-O-)-methyltransferaseMDVVSLDKPFMYFEEIDNELDYEPESANEVAKKLPYQGQLKLLLGELFFL...unknown
Eukaryotic translation initiation factor 4EMATVEPETTPTPNPPTTEEEKTESNQEVANPEHYIKHPLQNRWALWFFKN...unknown
Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS. Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682

Related Resource References

Resource NameReference
PubChem 444335, 135460973
ChEBI CHEBI:63730