Download MendeleyHuman Glutathione S-Transferase M1A-1A Catalyzes Formation of Gsh-Metal Complexes
Patskovsky, Y.V., Patskovska, L.N., Listowsky, I., Almo, S.C.To be published.
1YJ6
crystal structure of human glutathione S-transferase M1A-1A complexed with glutathionyl-zinc-trihydroxide
- PDB DOI: https://doi.org/10.2210/pdb1YJ6/pdb
- Classification: TRANSFERASE
- Organism(s): Homo sapiens
- Expression System: Escherichia coli BL21(DE3)
- Mutation(s): No
- Deposited: 2005-01-13 Released: 2005-02-01
Experimental Data Snapshot
- Method: X-RAY DIFFRACTION
- Resolution: 2.50 Å
- R-Value Free: 0.264
- R-Value Work: 0.230
- R-Value Observed: 0.230
Starting Model: experimental
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This is version 1.4 of the entry. See complete history.
Literature
To be published.
Macromolecules
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 1 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| Glutathione S-transferase Mu 1 | 218 | Homo sapiens | Mutation(s): 0 Gene Names: GSTM1, GST1 EC: 2.5.1.18 |  | |
UniProt & NIH Common Fund Data Resources | |||||
Find proteins for P09488 (Homo sapiens) Explore P09488 Go to UniProtKB: P09488 | |||||
PHAROS: P09488 GTEx: ENSG00000134184 | |||||
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
| UniProt Group | P09488 | ||||
Sequence AnnotationsExpand | |||||
| |||||
Small Molecules
| Ligands 2 Unique | |||||
|---|---|---|---|---|---|
| ID | Chains | Name / Formula / InChI Key | 2D Diagram | 3D Interactions | |
| GSH Query on GSH | E [auth A], G [auth B], I [auth C] | GLUTATHIONE C10 H17 N3 O6 S RWSXRVCMGQZWBV-WDSKDSINSA-N |  | ||
| ZN Query on ZN | D [auth A], F [auth B], H [auth C] | ZINC ION Zn PTFCDOFLOPIGGS-UHFFFAOYSA-N |  | ||
Experimental Data & Validation
Experimental Data
- Method: X-RAY DIFFRACTION
- Resolution: 2.50 Å
- R-Value Free: 0.264
- R-Value Work: 0.230
- R-Value Observed: 0.230
- Space Group: C 1 2 1
Unit Cell:
| Length ( Å ) | Angle ( ˚ ) |
|---|---|
| a = 178.64 | α = 90 |
| b = 51.41 | β = 122.47 |
| c = 93.82 | γ = 90 |
| Software Name | Purpose |
|---|---|
| SCALEPACK | data scaling |
| MOLREP | phasing |
| CNS | refinement |
| CCP4 | phasing |
Entry History
Deposition Data
- Released Date: 2005-02-01 Deposition Author(s): Patskovsky, Y.V., Patskovska, L.N., Listowsky, I., Almo, S.C.
Revision History (Full details and data files)
- Version 1.0: 2005-02-01
Type: Initial release - Version 1.1: 2008-04-30
Changes: Version format compliance - Version 1.2: 2011-07-13
Changes: Version format compliance - Version 1.3: 2017-10-11
Changes: Refinement description - Version 1.4: 2023-08-23
Changes: Data collection, Database references, Derived calculations, Refinement description
