Download MendeleyCrystal structures of phospholipases A2 from Vipera nikolskii venom revealing Triton X-100 bound in hydrophobic channel
Gao, W., Bi, R.C.To be published.
2I0U
Crystal structures of phospholipases A2 from Vipera nikolskii venom revealing Triton X-100 bound in hydrophobic channel
- PDB DOI: https://doi.org/10.2210/pdb2I0U/pdb
- Classification: HYDROLASE
- Organism(s): Vipera nikolskii
- Mutation(s): No
- Membrane Protein: Yes OPM
- Deposited: 2006-08-11 Released: 2007-09-11
Experimental Data Snapshot
- Method: X-RAY DIFFRACTION
- Resolution: 2.20 Å
- R-Value Free: 0.236
- R-Value Work: 0.209
- R-Value Observed: 0.209
This is version 1.2 of the entry. See complete history.
Literature
Macromolecules
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 1 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| Basic subunit of heterodimer phospholipase A2 | A [auth E], B [auth A] | 122 | Vipera nikolskii | Mutation(s): 0 EC: 3.1.1.4 Membrane Entity: Yes |  |
UniProt | |||||
Find proteins for Q1RP79 (Vipera nikolskii) Explore Q1RP79 Go to UniProtKB: Q1RP79 | |||||
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
| UniProt Group | Q1RP79 | ||||
Sequence AnnotationsExpand | |||||
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Small Molecules
| Ligands 4 Unique | |||||
|---|---|---|---|---|---|
| ID | Chains | Name / Formula / InChI Key | 2D Diagram | 3D Interactions | |
| TRT Query on TRT | F [auth E], H [auth A] | FRAGMENT OF TRITON X-100 C21 H36 O4 HEUDUECKTWTQQR-UHFFFAOYSA-N |  | ||
| TFA Query on TFA | I [auth A] | trifluoroacetic acid C2 H F3 O2 DTQVDTLACAAQTR-UHFFFAOYSA-N |  | ||
| SO4 Query on SO4 | E, G [auth A] | SULFATE ION O4 S QAOWNCQODCNURD-UHFFFAOYSA-L |  | ||
| CA Query on CA | C [auth E], D [auth E] | CALCIUM ION Ca BHPQYMZQTOCNFJ-UHFFFAOYSA-N |  | ||
Experimental Data & Validation
Experimental Data
- Method: X-RAY DIFFRACTION
- Resolution: 2.20 Å
- R-Value Free: 0.236
- R-Value Work: 0.209
- R-Value Observed: 0.209
- Space Group: H 3 2
Unit Cell:
| Length ( Å ) | Angle ( ˚ ) |
|---|---|
| a = 76.284 | α = 90 |
| b = 76.284 | β = 90 |
| c = 304.395 | γ = 120 |
| Software Name | Purpose |
|---|---|
| HKL-2000 | data collection |
| AMoRE | phasing |
| CNS | refinement |
| DENZO | data reduction |
| SCALEPACK | data scaling |
Entry History
Revision History (Full details and data files)
- Version 1.0: 2007-09-11
Type: Initial release - Version 1.1: 2011-07-13
Changes: Derived calculations, Version format compliance - Version 1.2: 2024-10-30
Changes: Data collection, Database references, Derived calculations, Structure summary
