Download MendeleyCrystal Structure of the Human Ribosomal Protein S6 Kinase
Muniz, J.R.C., Elkins, J.M., Wang, J., Ugochukwu, E., Salah, E., King, O., Picaud, S., von Delft, F., Bountra, C., Arrowsmith, C.H., Weigelt, J., Edwards, A., Knapp, S.To be published.
2WNT
Crystal Structure of the Human Ribosomal protein S6 kinase
- PDB DOI: https://doi.org/10.2210/pdb2WNT/pdb
- Classification: TRANSFERASE
- Organism(s): Homo sapiens
- Mutation(s): No
- Deposited: 2009-07-20 Released: 2009-08-25
Experimental Data Snapshot
- Method: X-RAY DIFFRACTION
- Resolution: 2.40 Å
- R-Value Free: 0.240
- R-Value Work: 0.189
- R-Value Observed: 0.193
wwPDB Validation 3D Report Full Report
This is version 1.4 of the entry. See complete history.
Literature
To be published.
Macromolecules
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 1 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| RIBOSOMAL PROTEIN S6 KINASE | 330 | Homo sapiens | Mutation(s): 0 EC: 2.7.11.1 |  | |
UniProt & NIH Common Fund Data Resources | |||||
Find proteins for Q15418 (Homo sapiens) Explore Q15418 Go to UniProtKB: Q15418 | |||||
PHAROS: Q15418 GTEx: ENSG00000117676 | |||||
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
| UniProt Group | Q15418 | ||||
Sequence AnnotationsExpand | |||||
| |||||
Small Molecules
| Ligands 3 Unique | |||||
|---|---|---|---|---|---|
| ID | Chains | Name / Formula / InChI Key | 2D Diagram | 3D Interactions | |
| PEG Query on PEG | G [auth B], H [auth B] | DI(HYDROXYETHYL)ETHER C4 H10 O3 MTHSVFCYNBDYFN-UHFFFAOYSA-N |  | ||
| CL Query on CL | F [auth B] | CHLORIDE ION Cl VEXZGXHMUGYJMC-UHFFFAOYSA-M |  | ||
| NA Query on NA | C [auth A], D [auth B], E [auth B] | SODIUM ION Na FKNQFGJONOIPTF-UHFFFAOYSA-N |  | ||
Experimental Data & Validation
Experimental Data
- Method: X-RAY DIFFRACTION
- Resolution: 2.40 Å
- R-Value Free: 0.240
- R-Value Work: 0.189
- R-Value Observed: 0.193
- Space Group: P 1 21 1
Unit Cell:
| Length ( Å ) | Angle ( ˚ ) |
|---|---|
| a = 39.66 | α = 90 |
| b = 142.91 | β = 94.9 |
| c = 60.96 | γ = 90 |
| Software Name | Purpose |
|---|---|
| PHENIX | refinement |
| MOSFLM | data reduction |
| SCALEPACK | data scaling |
| PHASER | phasing |
Entry History
Deposition Data
- Released Date: 2009-08-25 Deposition Author(s): Muniz, J.R.C., Elkins, J.M., Wang, J., Ugochukwu, E., Salah, E., King, O., Picaud, S., von Delft, F., Bountra, C., Arrowsmith, C.H., Weigelt, J., Edwards, A., Knapp, S.
Revision History (Full details and data files)
- Version 1.0: 2009-08-25
Type: Initial release - Version 1.1: 2011-05-08
Changes: Version format compliance - Version 1.2: 2011-07-13
Changes: Version format compliance - Version 1.3: 2018-01-24
Changes: Database references, Structure summary - Version 1.4: 2024-11-20
Changes: Data collection, Database references, Derived calculations, Other, Structure summary
