Download MendeleyStructural studies on PIN1 mutants
Jobichen, C., Liou, Y.C., Sivaraman, J.To be published.
2ZQS
Crystal structure of a mutant PIN1 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE
- PDB DOI: https://doi.org/10.2210/pdb2ZQS/pdb
- Classification: ISOMERASE
- Organism(s): Homo sapiens
- Expression System: Escherichia coli
- Mutation(s): Yes
- Deposited: 2008-08-19 Released: 2009-08-25
Experimental Data Snapshot
- Method: X-RAY DIFFRACTION
- Resolution: 1.90 Å
- R-Value Free: 0.284
- R-Value Work: 0.238
- R-Value Observed: 0.238
Starting Model: experimental
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wwPDB Validation 3D Report Full Report
This is version 1.3 of the entry. See complete history.
Literature
Macromolecules
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 1 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | 163 | Homo sapiens | Mutation(s): 1 Gene Names: PIN1 EC: 5.2.1.8 |  | |
UniProt & NIH Common Fund Data Resources | |||||
Find proteins for Q13526 (Homo sapiens) Explore Q13526 Go to UniProtKB: Q13526 | |||||
PHAROS: Q13526 GTEx: ENSG00000127445 | |||||
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
| UniProt Group | Q13526 | ||||
Sequence AnnotationsExpand | |||||
| |||||
Small Molecules
| Ligands 2 Unique | |||||
|---|---|---|---|---|---|
| ID | Chains | Name / Formula / InChI Key | 2D Diagram | 3D Interactions | |
| 1PG Query on 1PG | C [auth A] | 2-(2-{2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHANOL C11 H24 O6 SLNYBUIEAMRFSZ-UHFFFAOYSA-N |  | ||
| SO4 Query on SO4 | B [auth A] | SULFATE ION O4 S QAOWNCQODCNURD-UHFFFAOYSA-L |  | ||
Experimental Data & Validation
Experimental Data
- Method: X-RAY DIFFRACTION
- Resolution: 1.90 Å
- R-Value Free: 0.284
- R-Value Work: 0.238
- R-Value Observed: 0.238
- Space Group: P 43 21 2
Unit Cell:
| Length ( Å ) | Angle ( ˚ ) |
|---|---|
| a = 48.758 | α = 90 |
| b = 48.758 | β = 90 |
| c = 137.98 | γ = 90 |
| Software Name | Purpose |
|---|---|
| PHENIX | refinement |
| CrystalClear | data collection |
| HKL-2000 | data reduction |
| HKL-2000 | data scaling |
| PHASER | phasing |
Entry History
Deposition Data
- Released Date: 2009-08-25 Deposition Author(s): Jobichen, C., Liou, Y.C., Sivaraman, J.
Revision History (Full details and data files)
- Version 1.0: 2009-08-25
Type: Initial release - Version 1.1: 2011-07-13
Changes: Version format compliance - Version 1.2: 2021-11-10
Changes: Database references, Derived calculations - Version 1.3: 2023-11-01
Changes: Data collection, Refinement description
