Download MendeleyThe crystal structure of human adenosine deaminase
Ugochukwu, E., Zhang, Y., Hapka, E., Yue, W.W., Bray, J.E., Muniz, J., Burgess-Brown, N., Chaikuad, A., Kavanagh, K.L., Oppermann, U.To be published.
3IAR
The crystal structure of human adenosine deaminase
- PDB DOI: https://doi.org/10.2210/pdb3IAR/pdb
- Classification: HYDROLASE
- Organism(s): Homo sapiens
- Expression System: Escherichia coli
- Mutation(s): No
- Deposited: 2009-07-14 Released: 2009-08-11
Experimental Data Snapshot
- Method: X-RAY DIFFRACTION
- Resolution: 1.52 Å
- R-Value Free: 0.185
- R-Value Work: 0.153
- R-Value Observed: 0.154
Starting Model: experimental
View more details
This is version 1.2 of the entry. See complete history.
Literature
To be published.
Macromolecules
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 1 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| Adenosine deaminase | 367 | Homo sapiens | Mutation(s): 0 Gene Names: ADA EC: 3.5.4.4 |  | |
UniProt & NIH Common Fund Data Resources | |||||
Find proteins for P00813 (Homo sapiens) Explore P00813 Go to UniProtKB: P00813 | |||||
PHAROS: P00813 GTEx: ENSG00000196839 | |||||
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
| UniProt Group | P00813 | ||||
Sequence AnnotationsExpand | |||||
| |||||
Small Molecules
| Ligands 4 Unique | |||||
|---|---|---|---|---|---|
| ID | Chains | Name / Formula / InChI Key | 2D Diagram | 3D Interactions | |
| 3D1 Query on 3D1 | B [auth A] | (2R,3S,5R)-5-(6-amino-9H-purin-9-yl)-tetrahydro-2-(hydroxymethyl)furan-3-ol C10 H13 N5 O3 OLXZPDWKRNYJJZ-RRKCRQDMSA-N |  | ||
| GOL Query on GOL | F [auth A] | GLYCEROL C3 H8 O3 PEDCQBHIVMGVHV-UHFFFAOYSA-N |  | ||
| NO3 Query on NO3 | D [auth A], E [auth A] | NITRATE ION N O3 NHNBFGGVMKEFGY-UHFFFAOYSA-N |  | ||
| NI Query on NI | C [auth A] | NICKEL (II) ION Ni VEQPNABPJHWNSG-UHFFFAOYSA-N |  | ||
Experimental Data & Validation
Experimental Data
- Method: X-RAY DIFFRACTION
- Resolution: 1.52 Å
- R-Value Free: 0.185
- R-Value Work: 0.153
- R-Value Observed: 0.154
- Space Group: P 21 21 21
Unit Cell:
| Length ( Å ) | Angle ( ˚ ) |
|---|---|
| a = 61.07 | α = 90 |
| b = 73.51 | β = 90 |
| c = 76.66 | γ = 90 |
| Software Name | Purpose |
|---|---|
| CrystalClear | data collection |
| PHASER | phasing |
| PHENIX | refinement |
| MOSFLM | data reduction |
| SCALA | data scaling |
Entry History
Deposition Data
- Released Date: 2009-08-11 Deposition Author(s): Ugochukwu, E., Zhang, Y., Hapka, E., Yue, W.W., Bray, J.E., Muniz, J., Burgess-Brown, N., Chaikuad, A., von Delft, F., Bountra, C., Arrowsmith, C.H., Weigelt, J., Edwards, A., Kavanagh, K.L., Oppermann, U., Structural Genomics Consortium (SGC)
Revision History (Full details and data files)
- Version 1.0: 2009-08-11
Type: Initial release - Version 1.1: 2011-07-13
Changes: Non-polymer description, Version format compliance - Version 1.2: 2023-09-06
Changes: Data collection, Database references, Derived calculations, Refinement description
