Download MendeleyCrystal Structure of Human Baz2B in Complex with Fragment-4 N09496
R Bradley, A., Liu, Y., Krojer, T., Bountra, C., Arrowsmith, C.H., Edwards, A., Knapp, S., von Delft, F.To be published.
4CUS
Crystal structure of human BAZ2B in complex with fragment-4 N09496
- PDB DOI: https://doi.org/10.2210/pdb4CUS/pdb
- Classification: TRANSCRIPTION
- Organism(s): Homo sapiens
- Expression System: Escherichia coli BL21(DE3)
- Mutation(s): No
- Deposited: 2014-03-21 Released: 2014-04-02
Experimental Data Snapshot
- Method: X-RAY DIFFRACTION
- Resolution: 1.78 Å
- R-Value Free: 0.203
- R-Value Work: 0.167
- R-Value Observed: 0.168
wwPDB Validation 3D Report Full Report
This is version 1.2 of the entry. See complete history.
Literature
To be published.
Macromolecules
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 1 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| BROMODOMAIN ADJACENT TO ZINC FINGER DOMAIN PROTEIN 2B | 117 | Homo sapiens | Mutation(s): 0 |  | |
UniProt & NIH Common Fund Data Resources | |||||
Find proteins for Q9UIF8 (Homo sapiens) Explore Q9UIF8 Go to UniProtKB: Q9UIF8 | |||||
PHAROS: Q9UIF8 GTEx: ENSG00000123636 | |||||
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
| UniProt Group | Q9UIF8 | ||||
Sequence AnnotationsExpand | |||||
| |||||
Small Molecules
| Ligands 2 Unique | |||||
|---|---|---|---|---|---|
| ID | Chains | Name / Formula / InChI Key | 2D Diagram | 3D Interactions | |
| ES1 Query on ES1 | C [auth A] | quinolin-4-ol C9 H7 N O PMZDQRJGMBOQBF-UHFFFAOYSA-N |  | ||
| EDO Query on EDO | B [auth A], D [auth A], E [auth A], F [auth A], G [auth A] | 1,2-ETHANEDIOL C2 H6 O2 LYCAIKOWRPUZTN-UHFFFAOYSA-N |  | ||
Experimental Data & Validation
Experimental Data
- Method: X-RAY DIFFRACTION
- Resolution: 1.78 Å
- R-Value Free: 0.203
- R-Value Work: 0.167
- R-Value Observed: 0.168
- Space Group: C 2 2 21
Unit Cell:
| Length ( Å ) | Angle ( ˚ ) |
|---|---|
| a = 82.175 | α = 90 |
| b = 96.928 | β = 90 |
| c = 57.978 | γ = 90 |
| Software Name | Purpose |
|---|---|
| PHENIX | refinement |
| XDS | data reduction |
| Aimless | data scaling |
Entry History
Deposition Data
- Released Date: 2014-04-02 Deposition Author(s): Bradley, A.R., Liu, Y., Krojer, T., Bountra, C., Arrowsmith, C.H., Edwards, A., Knapp, S., von Delft, F.
Revision History (Full details and data files)
- Version 1.0: 2014-04-02
Type: Initial release - Version 1.1: 2018-01-24
Changes: Database references - Version 1.2: 2024-05-08
Changes: Data collection, Database references, Derived calculations, Other
