Download MendeleyAzide and Cyanide Have Different Inhibition Modes of Urate Oxidase
Gabison, L., Colloc'h, N., El Hajji, M., Castro, B., Chiadmi, M., Prange, T.To be published.
4FSK
Urate oxidase-azide complex in anaerobic conditions
- PDB DOI: https://doi.org/10.2210/pdb4FSK/pdb
- Classification: OXIDOREDUCTASE
- Organism(s): Aspergillus flavus
- Expression System: Saccharomyces cerevisiae
- Mutation(s): Yes
- Deposited: 2012-06-27 Released: 2013-07-03
Experimental Data Snapshot
- Method: X-RAY DIFFRACTION
- Resolution: 1.98 Å
- R-Value Work: 0.189
- R-Value Observed: 0.190
Starting Model: experimental
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wwPDB Validation 3D Report Full Report
This is version 2.2 of the entry. See complete history.
Literature
To be published.
Macromolecules
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 1 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| Uricase | 302 | Aspergillus flavus | Mutation(s): 1 Gene Names: uaZ, uox EC: 1.7.3.3 |  | |
UniProt | |||||
Find proteins for Q00511 (Aspergillus flavus) Explore Q00511 Go to UniProtKB: Q00511 | |||||
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
| UniProt Group | Q00511 | ||||
Sequence AnnotationsExpand | |||||
| |||||
Small Molecules
| Ligands 2 Unique | |||||
|---|---|---|---|---|---|
| ID | Chains | Name / Formula / InChI Key | 2D Diagram | 3D Interactions | |
| AZI Query on AZI | B [auth A], C [auth A], D [auth A] | AZIDE ION N3 IVRMZWNICZWHMI-UHFFFAOYSA-N |  | ||
| NA Query on NA | E [auth A] | SODIUM ION Na FKNQFGJONOIPTF-UHFFFAOYSA-N |  | ||
Experimental Data & Validation
Experimental Data
- Method: X-RAY DIFFRACTION
- Resolution: 1.98 Å
- R-Value Work: 0.189
- R-Value Observed: 0.190
- Space Group: I 2 2 2
Unit Cell:
| Length ( Å ) | Angle ( ˚ ) |
|---|---|
| a = 80.858 | α = 90 |
| b = 95.338 | β = 90 |
| c = 104.777 | γ = 90 |
| Software Name | Purpose |
|---|---|
| ADSC | data collection |
| SHELXL | refinement |
| SHELXL-97 | refinement |
| MOSFLM | data reduction |
| SCALA | data scaling |
| TRUNCATE | data scaling |
Entry History
Deposition Data
- Released Date: 2013-07-03 Deposition Author(s): Gabison, L., Colloc'h, N., El Hajji, M., Castro, B., Chiadmi, M., Prange, T.
Revision History (Full details and data files)
- Version 1.0: 2013-07-03
Type: Initial release - Version 1.1: 2018-02-28
Changes: Database references, Structure summary - Version 2.0: 2022-04-20
Changes: Advisory, Atomic model, Data collection, Database references, Derived calculations, Source and taxonomy, Structure summary - Version 2.1: 2023-09-13
Changes: Data collection, Refinement description - Version 2.2: 2024-11-27
Changes: Structure summary
