Download MendeleyCrystal structure of glucose 1-phosphate thymidylyltransferase from Aneurinibacillus thermoaerophilus complexed with TDP-glucose
Chen, T.J., Chien, W.T., Lin, C.C., Wang, W.C.To be published.
4HO5
Crystal structure of glucose 1-phosphate thymidylyltransferase from Aneurinibacillus thermoaerophilus complexed with TDP-glucose
- PDB DOI: https://doi.org/10.2210/pdb4HO5/pdb
- Classification: TRANSFERASE
- Organism(s): Aneurinibacillus thermoaerophilus
- Expression System: Escherichia coli
- Mutation(s): No
- Deposited: 2012-10-22 Released: 2013-10-23
Experimental Data Snapshot
- Method: X-RAY DIFFRACTION
- Resolution: 1.70 Å
- R-Value Free: 0.223
- R-Value Work: 0.192
- R-Value Observed: 0.194
This is version 1.2 of the entry. See complete history.
Literature
To be published.
Macromolecules
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 1 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| Glucose-1-phosphate thymidylyltransferase | 297 | Aneurinibacillus thermoaerophilus | Mutation(s): 0 Gene Names: rmlA EC: 2.7.7.24 |  | |
UniProt | |||||
Find proteins for Q9AGY4 (Aneurinibacillus thermoaerophilus) Explore Q9AGY4 Go to UniProtKB: Q9AGY4 | |||||
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
| UniProt Group | Q9AGY4 | ||||
Sequence AnnotationsExpand | |||||
| |||||
Small Molecules
| Ligands 2 Unique | |||||
|---|---|---|---|---|---|
| ID | Chains | Name / Formula / InChI Key | 2D Diagram | 3D Interactions | |
| DAU Query on DAU | C [auth A], D [auth A], H [auth B], I [auth B] | 2'DEOXY-THYMIDINE-5'-DIPHOSPHO-ALPHA-D-GLUCOSE C16 H26 N2 O16 P2 YSYKRGRSMLTJNL-URARBOGNSA-N |  | ||
| SO4 Query on SO4 | E [auth A], F [auth A], G [auth A], J [auth B], K [auth B] | SULFATE ION O4 S QAOWNCQODCNURD-UHFFFAOYSA-L |  | ||
Experimental Data & Validation
Experimental Data
- Method: X-RAY DIFFRACTION
- Resolution: 1.70 Å
- R-Value Free: 0.223
- R-Value Work: 0.192
- R-Value Observed: 0.194
- Space Group: C 1 2 1
Unit Cell:
| Length ( Å ) | Angle ( ˚ ) |
|---|---|
| a = 114.302 | α = 90 |
| b = 90.56 | β = 124.96 |
| c = 87.519 | γ = 90 |
| Software Name | Purpose |
|---|---|
| DENZO | data reduction |
| SCALEPACK | data scaling |
| REFMAC | refinement |
| PDB_EXTRACT | data extraction |
| HKL-2000 | data collection |
| HKL-2000 | data reduction |
| MOLREP | phasing |
Entry History
Deposition Data
- Released Date: 2013-10-23 Deposition Author(s): Chen, T.J., Chien, W.T., Lin, C.C., Wang, W.C.
Revision History (Full details and data files)
- Version 1.0: 2013-10-23
Type: Initial release - Version 1.1: 2017-11-15
Changes: Refinement description - Version 1.2: 2024-02-28
Changes: Data collection, Database references, Derived calculations
