Download MendeleyThe crystal structure of phosphoribosylaminoimidazole carboxylase ATPase subunit of Francisella tularensis subsp. tularensis SCHU S4 in complex with an ADP analog, AMP-CP
Tan, K., Zhou, M., Kwon, K., Anderson, W.F., Joachimiak, A.To be published.
4MAM
The crystal structure of phosphoribosylaminoimidazole carboxylase ATPase subunit of Francisella tularensis subsp. tularensis SCHU S4 in complex with an ADP analog, AMP-CP
- PDB DOI: https://doi.org/10.2210/pdb4MAM/pdb
- Classification: LYASE
- Organism(s): Francisella tularensis subsp. tularensis SCHU S4
- Expression System: Escherichia coli BL21(DE3)
- Mutation(s): No
- Deposited: 2013-08-16 Released: 2013-08-28
Experimental Data Snapshot
- Method: X-RAY DIFFRACTION
- Resolution: 1.47 Å
- R-Value Free: 0.177
- R-Value Work: 0.160
- R-Value Observed: 0.161
Starting Model: experimental
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This is version 1.3 of the entry. See complete history.
Literature
To be published.
Macromolecules
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 1 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| Phosphoribosylaminoimidazole carboxylase, ATPase subunit | 373 | Francisella tularensis subsp. tularensis SCHU S4 | Mutation(s): 0 Gene Names: FTT_0897, purK EC: 4.1.1.21 (PDB Primary Data), 6.3.4.18 (UniProt) |  | |
UniProt | |||||
Find proteins for Q5NGE8 (Francisella tularensis subsp. tularensis (strain SCHU S4 / Schu 4)) Explore Q5NGE8 Go to UniProtKB: Q5NGE8 | |||||
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
| UniProt Group | Q5NGE8 | ||||
Sequence AnnotationsExpand | |||||
| |||||
Small Molecules
| Ligands 2 Unique | |||||
|---|---|---|---|---|---|
| ID | Chains | Name / Formula / InChI Key | 2D Diagram | 3D Interactions | |
| A12 Query on A12 | C [auth A], F [auth B] | PHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER C11 H17 N5 O9 P2 OLCWZBFDIYXLAA-IOSLPCCCSA-N |  | ||
| GOL Query on GOL | D [auth A], E [auth A], G [auth B] | GLYCEROL C3 H8 O3 PEDCQBHIVMGVHV-UHFFFAOYSA-N |  | ||
| Modified Residues 1 Unique | |||||
|---|---|---|---|---|---|
| ID | Chains | Type | Formula | 2D Diagram | Parent |
| MSE Query on MSE | A, B | L-PEPTIDE LINKING | C5 H11 N O2 Se |  | MET |
Experimental Data & Validation
Experimental Data
- Method: X-RAY DIFFRACTION
- Resolution: 1.47 Å
- R-Value Free: 0.177
- R-Value Work: 0.160
- R-Value Observed: 0.161
- Space Group: P 21 21 21
- Diffraction Data: https://doi.org/10.18430/m34mam
Unit Cell:
| Length ( Å ) | Angle ( ˚ ) |
|---|---|
| a = 73.241 | α = 90 |
| b = 85.393 | β = 90 |
| c = 127.12 | γ = 90 |
| Software Name | Purpose |
|---|---|
| SBC-Collect | data collection |
| MOLREP | phasing |
| PHENIX | refinement |
| HKL-3000 | data reduction |
| HKL-3000 | data scaling |
Entry History
Deposition Data
- Released Date: 2013-08-28 Deposition Author(s): Tan, K., Zhou, M., Kwon, K., Anderson, W.F., Joachimiak, A., Center for Structural Genomics of Infectious Diseases (CSGID)
Revision History (Full details and data files)
- Version 1.0: 2013-08-28
Type: Initial release - Version 1.1: 2016-12-21
Changes: Structure summary - Version 1.2: 2023-09-20
Changes: Data collection, Database references, Derived calculations, Refinement description - Version 1.3: 2023-12-06
Changes: Data collection
