Structure of Neisseria meningitidis 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase regulated and complexed with PEP at 2.05 Angstroms
Heyes, L.C., Parker, E.J.To be published.
Experimental Data Snapshot
Entity ID: 1 | |||||
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Molecule | Chains | Sequence Length | Organism | Details | Image |
Phospho-2-dehydro-3-deoxyheptonate aldolase | 351 | Neisseria meningitidis MC58 | Mutation(s): 0  Gene Names: aroG, NMB0307 EC: 2.5.1.54 | ||
UniProt | |||||
Find proteins for Q9K169 (Neisseria meningitidis serogroup B (strain ATCC BAA-335 / MC58)) Explore Q9K169  Go to UniProtKB:  Q9K169 | |||||
Entity Groups   | |||||
Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
UniProt Group | Q9K169 | ||||
Sequence AnnotationsExpand | |||||
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Ligands 8 Unique | |||||
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ID | Chains | Name / Formula / InChI Key | 2D Diagram | 3D Interactions | |
PEP Query on PEP | K [auth A], P [auth B], T [auth C], Y [auth D] | PHOSPHOENOLPYRUVATE C3 H5 O6 P DTBNBXWJWCWCIK-UHFFFAOYSA-N | |||
PHE Query on PHE | L [auth A], Q [auth B], U [auth C], Z [auth D] | PHENYLALANINE C9 H11 N O2 COLNVLDHVKWLRT-QMMMGPOBSA-N | |||
PGE Query on PGE | J [auth A] | TRIETHYLENE GLYCOL C6 H14 O4 ZIBGPFATKBEMQZ-UHFFFAOYSA-N | |||
PEG Query on PEG | I [auth A], X [auth D] | DI(HYDROXYETHYL)ETHER C4 H10 O3 MTHSVFCYNBDYFN-UHFFFAOYSA-N | |||
SO4 Query on SO4 | F [auth A] | SULFATE ION O4 S QAOWNCQODCNURD-UHFFFAOYSA-L | |||
EDO Query on EDO | G [auth A], H [auth A], O [auth B], W [auth D] | 1,2-ETHANEDIOL C2 H6 O2 LYCAIKOWRPUZTN-UHFFFAOYSA-N | |||
MN Query on MN | E [auth A], N [auth B], S [auth C], V [auth D] | MANGANESE (II) ION Mn WAEMQWOKJMHJLA-UHFFFAOYSA-N | |||
CL Query on CL | AA [auth D], M [auth A], R [auth B] | CHLORIDE ION Cl VEXZGXHMUGYJMC-UHFFFAOYSA-M |
Length ( Å ) | Angle ( ˚ ) |
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a = 75.458 | α = 90 |
b = 140.31 | β = 96.89 |
c = 75.5 | γ = 90 |
Software Name | Purpose |
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REFMAC | refinement |
XDS | data reduction |
Aimless | data scaling |
PHASER | phasing |