Download MendeleyCrystal Structure and Potential Head-to-Middle Condensation Function of a Z,Z-Farnesyl Diphosphate Synthase
Chan, Y.T., Ko, T.P., Yao, S.H., Chen, Y.W., Lee, C.C., Wang, A.H.J.(2017) ACS Omega 2: 930-936
5HXT
Crystal Structure of Z,Z-Farnesyl Diphosphate Synthase (D71M, E75A and H103Y Mutants) Complexed with IPP and DMSPP
- PDB DOI: https://doi.org/10.2210/pdb5HXT/pdb
- Classification: TRANSFERASE
- Organism(s): Solanum habrochaites
- Expression System: Escherichia coli BL21(DE3)
- Mutation(s): Yes
- Deposited: 2016-01-31 Released: 2017-04-05
Experimental Data Snapshot
- Method: X-RAY DIFFRACTION
- Resolution: 2.15 Å
- R-Value Free: 0.249
- R-Value Work: 0.197
- R-Value Observed: 0.199
Starting Model: experimental
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This is version 2.1 of the entry. See complete history.
Literature
Macromolecules
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 1 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| (2Z,6Z)-farnesyl diphosphate synthase, chloroplastic | 233 | Solanum habrochaites | Mutation(s): 2 Gene Names: ZFPS EC: 2.5.1.92 |  | |
UniProt | |||||
Find proteins for B8XA40 (Solanum habrochaites) Explore B8XA40 Go to UniProtKB: B8XA40 | |||||
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
| UniProt Group | B8XA40 | ||||
Sequence AnnotationsExpand | |||||
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Small Molecules
| Ligands 4 Unique | |||||
|---|---|---|---|---|---|
| ID | Chains | Name / Formula / InChI Key | 2D Diagram | 3D Interactions | |
| O4B Query on O4B | I [auth B] | 1,4,7,10,13,16-HEXAOXACYCLOOCTADECANE C12 H24 O6 XEZNGIUYQVAUSS-UHFFFAOYSA-N |  | ||
| DST Query on DST | D [auth A], G [auth B] | DIMETHYLALLYL S-THIOLODIPHOSPHATE C5 H12 O6 P2 S ZWFWSISPSBLNGO-UHFFFAOYSA-N |  | ||
| IPR Query on IPR | E [auth A], H [auth B] | ISOPENTYL PYROPHOSPHATE C5 H14 O7 P2 IPFXNYPSBSIFOB-UHFFFAOYSA-N |  | ||
| MG Query on MG | C [auth A], F [auth B] | MAGNESIUM ION Mg JLVVSXFLKOJNIY-UHFFFAOYSA-N |  | ||
Experimental Data & Validation
Experimental Data
- Method: X-RAY DIFFRACTION
- Resolution: 2.15 Å
- R-Value Free: 0.249
- R-Value Work: 0.197
- R-Value Observed: 0.199
- Space Group: P 21 21 21
Unit Cell:
| Length ( Å ) | Angle ( ˚ ) |
|---|---|
| a = 59.981 | α = 90 |
| b = 66.321 | β = 90 |
| c = 128.939 | γ = 90 |
| Software Name | Purpose |
|---|---|
| REFMAC | refinement |
| HKL-2000 | data processing |
| HKL-2000 | data scaling |
| MOLREP | phasing |
Entry History
Deposition Data
- Released Date: 2017-04-05 Deposition Author(s): Lee, C.C., Chan, Y.T., Wang, A.H.J.
Revision History (Full details and data files)
- Version 1.0: 2017-04-05
Type: Initial release - Version 2.0: 2019-10-16
Changes: Data collection, Database references, Non-polymer description, Structure summary - Version 2.1: 2023-11-08
Changes: Data collection, Database references, Derived calculations, Refinement description, Structure summary
