Crystal structure of mouse CARM1 in complex with SAH at 1.8 Angstroms resolution
Cura, V., Marechal, N., Mailliot, J., Troffer-Charlier, N., Wurtz, J.M., Bonnefond, L., Cavarelli, J.To be published.
Experimental Data Snapshot
Starting Model: experimental
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Entity ID: 1 | |||||
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Molecule | Chains | Sequence Length | Organism | Details | Image |
Histone-arginine methyltransferase CARM1 | 361 | Mus musculus | Mutation(s): 0  Gene Names: Carm1, Prmt4 EC: 2.1.1.319 | ||
UniProt & NIH Common Fund Data Resources | |||||
Find proteins for Q9WVG6 (Mus musculus) Explore Q9WVG6  Go to UniProtKB:  Q9WVG6 | |||||
IMPC:  MGI:1913208 | |||||
Entity Groups   | |||||
Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
UniProt Group | Q9WVG6 | ||||
Sequence AnnotationsExpand | |||||
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Ligands 6 Unique | |||||
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ID | Chains | Name / Formula / InChI Key | 2D Diagram | 3D Interactions | |
SAH Query on SAH | BA [auth D], E [auth A], L [auth B], T [auth C] | S-ADENOSYL-L-HOMOCYSTEINE C14 H20 N6 O5 S ZJUKTBDSGOFHSH-WFMPWKQPSA-N | |||
PE8 Query on PE8 | Q [auth B] | 3,6,9,12,15,18,21-HEPTAOXATRICOSANE-1,23-DIOL C16 H34 O9 GLZWNFNQMJAZGY-UHFFFAOYSA-N | |||
PGE Query on PGE | K [auth A] | TRIETHYLENE GLYCOL C6 H14 O4 ZIBGPFATKBEMQZ-UHFFFAOYSA-N | |||
PEG Query on PEG | H [auth A] I [auth A] J [auth A] P [auth B] X [auth C] | DI(HYDROXYETHYL)ETHER C4 H10 O3 MTHSVFCYNBDYFN-UHFFFAOYSA-N | |||
DXE Query on DXE | AA [auth C], R [auth B], S [auth B], Z [auth C] | 1,2-DIMETHOXYETHANE C4 H10 O2 XTHFKEDIFFGKHM-UHFFFAOYSA-N | |||
EDO Query on EDO | CA [auth D] DA [auth D] EA [auth D] F [auth A] G [auth A] | 1,2-ETHANEDIOL C2 H6 O2 LYCAIKOWRPUZTN-UHFFFAOYSA-N |
Length ( Å ) | Angle ( ˚ ) |
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a = 74.628 | α = 90 |
b = 97.92 | β = 90 |
c = 204.955 | γ = 90 |
Software Name | Purpose |
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PHENIX | refinement |
XDS | data reduction |
Aimless | data scaling |
Funding Organization | Location | Grant Number |
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France | -- |