Download MendeleyPanDDA analysis group deposition
Newman, J.A., Katis, V.L., Gavard, A.E., von Delft, F., Arrowsmith, C.H., Edwards, A., Bountra, C., Gileadi, O.To be published.
5QSW
PanDDA analysis group deposition -- Crystal Structure of human STAG1 in complex with Z2856434884
- PDB DOI: https://doi.org/10.2210/pdb5QSW/pdb
- Deposition Group: G_1002084 (changed state) ExploreG_1002084
- Classification: TRANSCRIPTION
- Organism(s): Homo sapiens
- Expression System: Escherichia coli
- Mutation(s): No
- Deposited: 2019-05-25 Released: 2019-08-21
Experimental Data Snapshot
- Method: X-RAY DIFFRACTION
- Resolution: 3.03 Å
- R-Value Free: 0.267
- R-Value Work: 0.187
- R-Value Observed: 0.191
This is version 1.1 of the entry. See complete history.
Literature
To be published.
Macromolecules
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 1 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| Cohesin subunit SA-1 | A [auth C], B [auth A], C [auth B], D | 339 | Homo sapiens | Mutation(s): 0 Gene Names: STAG1, SA1, SCC3 |  |
UniProt & NIH Common Fund Data Resources | |||||
Find proteins for Q8WVM7 (Homo sapiens) Explore Q8WVM7 Go to UniProtKB: Q8WVM7 | |||||
PHAROS: Q8WVM7 GTEx: ENSG00000118007 | |||||
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
| UniProt Group | Q8WVM7 | ||||
Sequence AnnotationsExpand | |||||
| |||||
Small Molecules
| Ligands 1 Unique | |||||
|---|---|---|---|---|---|
| ID | Chains | Name / Formula / InChI Key | 2D Diagram | 3D Interactions | |
| O3J (Subject of Investigation/LOI) Query on O3J | E [auth C], F [auth A], G [auth B], H [auth D] | 1-[4-(3-phenylpropyl)piperazin-1-yl]ethan-1-one C15 H22 N2 O XQYKCRQRBYLELO-UHFFFAOYSA-N |  | ||
Experimental Data & Validation
Experimental Data
- Method: X-RAY DIFFRACTION
- Resolution: 3.03 Å
- R-Value Free: 0.267
- R-Value Work: 0.187
- R-Value Observed: 0.191
- Space Group: P 1
Unit Cell:
| Length ( Å ) | Angle ( ˚ ) |
|---|---|
| a = 66.489 | α = 94.89 |
| b = 72.409 | β = 98.6 |
| c = 118.515 | γ = 115.59 |
| Software Name | Purpose |
|---|---|
| REFMAC | refinement |
| Aimless | data scaling |
| PDB_EXTRACT | data extraction |
| XDS | data reduction |
| REFMAC | phasing |
Entry History
Deposition Data
- Released Date: 2019-08-21 Deposition Author(s): Newman, J.A., Katis, V.L., Gavard, A.E., von Delft, F., Arrowsmith, C.H., Edwards, A., Bountra, C., Gileadi, O.
Revision History (Full details and data files)
- Version 1.0: 2019-08-21
Type: Initial release - Version 1.1: 2024-03-06
Changes: Data collection, Database references
