Download MendeleyHIV-1 CA hexamer with NUP153 peptide - R3 crystal form
Skorupka, K., Zadrozny, K., Ganser-Pornillos, B.K., Pornillos, O.To be published.
5TSV
HIV-1 CA hexamer with NUP153 peptide - R3 crystal form
- PDB DOI: https://doi.org/10.2210/pdb5TSV/pdb
- Classification: VIRAL PROTEIN
- Organism(s): Human immunodeficiency virus type 1 (NEW YORK-5 ISOLATE), Homo sapiens
- Expression System: Escherichia coli BL21(DE3)
- Mutation(s): Yes
- Deposited: 2016-10-31 Released: 2017-11-08
- Funding Organization(s): National Institutes of Health/National Institute Of Allergy and Infectious Diseases (NIH/NIAID), National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS)
Experimental Data Snapshot
- Method: X-RAY DIFFRACTION
- Resolution: 2.50 Å
- R-Value Free: 0.251
- R-Value Work: 0.203
- R-Value Observed: 0.208
Starting Model: experimental
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This is version 1.3 of the entry. See complete history.
Literature
To be published.
Macromolecules
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 1 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| HIV-1 CA protein | 231 | Human immunodeficiency virus type 1 (NEW YORK-5 ISOLATE) | Mutation(s): 4 Gene Names: gag |  | |
UniProt | |||||
Find proteins for P12493 (Human immunodeficiency virus type 1 group M subtype B (isolate NY5)) Explore P12493 Go to UniProtKB: P12493 | |||||
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
| UniProt Group | P12493 | ||||
Sequence AnnotationsExpand | |||||
| |||||
Find similar proteins by: Sequence | 3D Structure
Entity ID: 2 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| Nuclear pore complex protein Nup153 | C [auth D] | 23 | Homo sapiens | Mutation(s): 0 |  |
UniProt & NIH Common Fund Data Resources | |||||
Find proteins for P49790 (Homo sapiens) Explore P49790 Go to UniProtKB: P49790 | |||||
PHAROS: P49790 GTEx: ENSG00000124789 | |||||
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
| UniProt Group | P49790 | ||||
Sequence AnnotationsExpand | |||||
| |||||
Small Molecules
| Ligands 1 Unique | |||||
|---|---|---|---|---|---|
| ID | Chains | Name / Formula / InChI Key | 2D Diagram | 3D Interactions | |
| FLU Query on FLU | D [auth B] | 2-(6-HYDROXY-3-OXO-3H-XANTHEN-9-YL)-BENZOIC ACID C20 H12 O5 YKGGGCXBWXHKIZ-UHFFFAOYSA-N |  | ||
Experimental Data & Validation
Experimental Data
- Method: X-RAY DIFFRACTION
- Resolution: 2.50 Å
- R-Value Free: 0.251
- R-Value Work: 0.203
- R-Value Observed: 0.208
- Space Group: H 3
Unit Cell:
| Length ( Å ) | Angle ( ˚ ) |
|---|---|
| a = 151.924 | α = 90 |
| b = 151.924 | β = 90 |
| c = 69.646 | γ = 120 |
| Software Name | Purpose |
|---|---|
| PHENIX | refinement |
| HKL-2000 | data reduction |
| HKL-2000 | data scaling |
| PHENIX | phasing |
Entry History & Funding Information
Deposition Data
- Released Date: 2017-11-08 Deposition Author(s): Skorupka, K., Ganser-Pornillos, B.K., Pornillos, O.
| Funding Organization | Location | Grant Number |
|---|---|---|
| National Institutes of Health/National Institute Of Allergy and Infectious Diseases (NIH/NIAID) | United States | R01-AI120956 |
| National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS) | United States | P50-GM103297 |
Revision History (Full details and data files)
- Version 1.0: 2017-11-08
Type: Initial release - Version 1.1: 2019-12-11
Changes: Author supporting evidence - Version 1.2: 2023-10-04
Changes: Data collection, Database references, Derived calculations, Refinement description - Version 1.3: 2024-10-23
Changes: Structure summary
