Structural Variants of Transthyretin
Saelices, L., Chung, K., Esswein, S., Chou, J., Liang, W., Li, J.H., Sawaya, M.R., Cascio, D., Eisenberg, D.To be published.
Experimental Data Snapshot
wwPDB Validation   3D Report Full Report
Entity ID: 1 | |||||
---|---|---|---|---|---|
Molecule | Chains | Sequence Length | Organism | Details | Image |
Transthyretin | 115 | Homo sapiens | Mutation(s): 2  Gene Names: TTR, PALB | ||
UniProt & NIH Common Fund Data Resources | |||||
Find proteins for P02766 (Homo sapiens) Explore P02766  Go to UniProtKB:  P02766 | |||||
PHAROS:  P02766 GTEx:  ENSG00000118271  | |||||
Entity Groups   | |||||
Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
UniProt Group | P02766 | ||||
Sequence AnnotationsExpand | |||||
|
Ligands 3 Unique | |||||
---|---|---|---|---|---|
ID | Chains | Name / Formula / InChI Key | 2D Diagram | 3D Interactions | |
SO4 Query on SO4 | E [auth B] | SULFATE ION O4 S QAOWNCQODCNURD-UHFFFAOYSA-L | |||
GOL Query on GOL | C [auth A], D [auth A] | GLYCEROL C3 H8 O3 PEDCQBHIVMGVHV-UHFFFAOYSA-N | |||
ACT Query on ACT | F [auth B], G [auth B] | ACETATE ION C2 H3 O2 QTBSBXVTEAMEQO-UHFFFAOYSA-M |
Modified Residues 1 Unique | |||||
---|---|---|---|---|---|
ID | Chains | Type | Formula | 2D Diagram | Parent |
OCS Query on OCS | A, B | L-PEPTIDE LINKING | C3 H7 N O5 S | CYS |
Length ( Å ) | Angle ( ˚ ) |
---|---|
a = 43.33 | α = 90 |
b = 85.33 | β = 90 |
c = 63.51 | γ = 90 |
Software Name | Purpose |
---|---|
XSCALE | data scaling |
PHENIX | refinement |
PDB_EXTRACT | data extraction |
XDS | data reduction |
Funding Organization | Location | Grant Number |
---|---|---|
National Institutes of Health/National Institute on Aging (NIH/NIA) | United States | AG048120 |