Blood group synthase AAGlyB in complex with UDP-Gal and cryoprotected with PEG 3350
Rocha, J., Batot, G.O., Palcic, M.M., Breton, C., Royant, A.To be published.
Experimental Data Snapshot
Starting Model: experimental
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Entity ID: 1 | |||||
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Molecule | Chains | Sequence Length | Organism | Details | Image |
ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase transferase B, alpha 1-3-galactosyltransferase) | 298 | Homo sapiens | Mutation(s): 1  Gene Names: ABO EC: 2.4.1.40 (UniProt), 2.4.1.37 (UniProt) | ||
UniProt & NIH Common Fund Data Resources | |||||
Find proteins for P16442 (Homo sapiens) Explore P16442  Go to UniProtKB:  P16442 | |||||
PHAROS:  P16442 | |||||
Entity Groups   | |||||
Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
UniProt Group | P16442 | ||||
Sequence AnnotationsExpand | |||||
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Ligands 5 Unique | |||||
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ID | Chains | Name / Formula / InChI Key | 2D Diagram | 3D Interactions | |
GDU Query on GDU | C [auth A] | GALACTOSE-URIDINE-5'-DIPHOSPHATE C15 H24 N2 O17 P2 HSCJRCZFDFQWRP-ABVWGUQPSA-N | |||
PEG Query on PEG | G [auth A] | DI(HYDROXYETHYL)ETHER C4 H10 O3 MTHSVFCYNBDYFN-UHFFFAOYSA-N | |||
SO4 Query on SO4 | D [auth A], E [auth A], F [auth A] | SULFATE ION O4 S QAOWNCQODCNURD-UHFFFAOYSA-L | |||
EDO Query on EDO | H [auth A], I [auth A], J [auth A] | 1,2-ETHANEDIOL C2 H6 O2 LYCAIKOWRPUZTN-UHFFFAOYSA-N | |||
MN Query on MN | B [auth A] | MANGANESE (II) ION Mn WAEMQWOKJMHJLA-UHFFFAOYSA-N |
Length ( Å ) | Angle ( ˚ ) |
---|---|
a = 52.849 | α = 90 |
b = 148.92 | β = 90 |
c = 80.039 | γ = 90 |
Software Name | Purpose |
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REFMAC | refinement |
XDS | data reduction |
Aimless | data scaling |
REFMAC | phasing |
Funding Organization | Location | Grant Number |
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French National Research Agency | France | ANR-13-BSV8-0011-02 |