Download MendeleyHuman PARP16 (ARTD15) IN COMPLEX WITH EB-47
Karlberg, T., Pinto, A.F., Thorsell, A.G., Schuler, H.To be published.
6HXR
Human PARP16 (ARTD15) IN COMPLEX WITH EB-47
- PDB DOI: https://doi.org/10.2210/pdb6HXR/pdb
- Classification: TRANSFERASE
- Organism(s): Homo sapiens
- Expression System: Escherichia coli
- Mutation(s): No
- Deposited: 2018-10-18 Released: 2019-10-30
Experimental Data Snapshot
- Method: X-RAY DIFFRACTION
- Resolution: 2.90 Å
- R-Value Free: 0.230
- R-Value Work: 0.199
- R-Value Observed: 0.201
Starting Model: experimental
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This is version 1.2 of the entry. See complete history.
Literature
To be published.
Macromolecules
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 1 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| Mono [ADP-ribose] polymerase PARP16 | 298 | Homo sapiens | Mutation(s): 0 Gene Names: PARP16, ARTD15, C15orf30 EC: 2.4.2.30 (PDB Primary Data), 2.4.2 (UniProt) |  | |
UniProt & NIH Common Fund Data Resources | |||||
Find proteins for Q8N5Y8 (Homo sapiens) Explore Q8N5Y8 Go to UniProtKB: Q8N5Y8 | |||||
PHAROS: Q8N5Y8 GTEx: ENSG00000138617 | |||||
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
| UniProt Group | Q8N5Y8 | ||||
Sequence AnnotationsExpand | |||||
| |||||
Small Molecules
| Ligands 1 Unique | |||||
|---|---|---|---|---|---|
| ID | Chains | Name / Formula / InChI Key | 2D Diagram | 3D Interactions | |
| UHB Query on UHB | D [auth A], E [auth B] | 2-[4-[(2S,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]carbonylpiperazin-1-yl]-N-(1-oxidanylidene-2,3-dihydroisoindol-4-yl)ethanamide C24 H27 N9 O6 QEUOCRGVJJDDTK-VBFAUCSFSA-N |  | ||
Experimental Data & Validation
Experimental Data
- Method: X-RAY DIFFRACTION
- Resolution: 2.90 Å
- R-Value Free: 0.230
- R-Value Work: 0.199
- R-Value Observed: 0.201
- Space Group: P 43 21 2
Unit Cell:
| Length ( Å ) | Angle ( ˚ ) |
|---|---|
| a = 148.064 | α = 90 |
| b = 148.064 | β = 90 |
| c = 99.73 | γ = 90 |
| Software Name | Purpose |
|---|---|
| BUSTER | refinement |
| XDS | data reduction |
| XDS | data scaling |
| PHASER | phasing |
Entry History
Deposition Data
- Released Date: 2019-10-30 Deposition Author(s): Karlberg, T., Pinto, A.F., Thorsell, A.G., Schuler, H.
Revision History (Full details and data files)
- Version 1.0: 2019-10-30
Type: Initial release - Version 1.1: 2022-12-07
Changes: Database references, Derived calculations - Version 1.2: 2024-01-31
Changes: Data collection, Refinement description
