Hsp90-alpha N-domain bound to NECA
Huck, J.D., Gewirth, D.T.To be published.
Experimental Data Snapshot
Starting Model: experimental
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Entity ID: 1 | |||||
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Molecule | Chains | Sequence Length | Organism | Details | Image |
Heat shock protein HSP 90-alpha | 256 | Homo sapiens | Mutation(s): 0  Gene Names: HSP90AA1, HSP90A, HSPC1, HSPCA EC: 3.6.4.10 | ||
UniProt & NIH Common Fund Data Resources | |||||
Find proteins for P07900 (Homo sapiens) Explore P07900  Go to UniProtKB:  P07900 | |||||
PHAROS:  P07900 GTEx:  ENSG00000080824  | |||||
Entity Groups   | |||||
Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
UniProt Group | P07900 | ||||
Sequence AnnotationsExpand | |||||
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Ligands 1 Unique | |||||
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ID | Chains | Name / Formula / InChI Key | 2D Diagram | 3D Interactions | |
NEC (Subject of Investigation/LOI) Query on NEC | B [auth A] | N-ETHYL-5'-CARBOXAMIDO ADENOSINE C12 H16 N6 O4 JADDQZYHOWSFJD-FLNNQWSLSA-N |
Length ( Å ) | Angle ( ˚ ) |
---|---|
a = 64.547 | α = 90 |
b = 90.077 | β = 90 |
c = 98.409 | γ = 90 |
Software Name | Purpose |
---|---|
PHENIX | refinement |
HKL-2000 | data reduction |
HKL-2000 | data scaling |
PHENIX | phasing |
Funding Organization | Location | Grant Number |
---|---|---|
National Institutes of Health/National Cancer Institute (NIH/NCI) | United States | P01-CA186866 |
National Institutes of Health/National Cancer Institute (NIH/NCI) | United States | R01-CA095130 |
Avon Foundation | United States | 02-2016-079 |
Goode Foundation of Buffalo | United States | -- |