Download MendeleySalmonella typhimurium neuraminidase mutant (D62G)
Garman, E.F., Salinger, M.T., Laver, W.G., Kuhn, P., Pape, T., Schneider, T.R., Sheldrick, G.M., Vimr, E.R.To be published.
7AF2
Salmonella typhimurium neuraminidase mutant (D62G)
- PDB DOI: https://doi.org/10.2210/pdb7AF2/pdb
- Classification: HYDROLASE
- Organism(s): Salmonella enterica subsp. enterica serovar Typhimurium
- Expression System: Escherichia coli
- Mutation(s): Yes
- Deposited: 2020-09-19 Released: 2020-09-30
Experimental Data Snapshot
- Method: X-RAY DIFFRACTION
- Resolution: 0.79 Å
- R-Value Free: 0.132
- R-Value Work: 0.121
Starting Model: experimental
View more details
wwPDB Validation 3D Report Full Report
This is version 1.2 of the entry. See complete history.
Literature
To be published.
Macromolecules
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 1 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| Sialidase | A [auth AAA] | 379 | Salmonella enterica subsp. enterica serovar Typhimurium | Mutation(s): 1 Gene Names: nanH, STM0928 EC: 3.2.1.18 |  |
UniProt | |||||
Find proteins for P29768 (Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)) Explore P29768 Go to UniProtKB: P29768 | |||||
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
| UniProt Group | P29768 | ||||
Sequence AnnotationsExpand | |||||
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Small Molecules
| Ligands 2 Unique | |||||
|---|---|---|---|---|---|
| ID | Chains | Name / Formula / InChI Key | 2D Diagram | 3D Interactions | |
| PO4 Query on PO4 | F [auth AAA] | PHOSPHATE ION O4 P NBIIXXVUZAFLBC-UHFFFAOYSA-K |  | ||
| GOL Query on GOL | B [auth AAA], C [auth AAA], D [auth AAA], E [auth AAA], G [auth AAA] | GLYCEROL C3 H8 O3 PEDCQBHIVMGVHV-UHFFFAOYSA-N |  | ||
Experimental Data & Validation
Experimental Data
- Method: X-RAY DIFFRACTION
- Resolution: 0.79 Å
- R-Value Free: 0.132
- R-Value Work: 0.121
- Space Group: P 21 21 21
Unit Cell:
| Length ( Å ) | Angle ( ˚ ) |
|---|---|
| a = 46.914 | α = 90 |
| b = 81.357 | β = 90 |
| c = 91.053 | γ = 90 |
| Software Name | Purpose |
|---|---|
| REFMAC | refinement |
| MOSFLM | data reduction |
| SCALA | data scaling |
| PHASER | phasing |
Entry History
Deposition Data
- Released Date: 2020-09-30 Deposition Author(s): Salinger, M.T., Kuhn, P., Laver, W.G., Pape, T., Schneider, T.R., Sheldrick, G.M., Vimr, E.R., Garman, E.F.
Revision History (Full details and data files)
- Version 1.0: 2020-09-30
Type: Initial release - Version 1.1: 2024-01-31
Changes: Advisory, Data collection, Database references, Derived calculations, Refinement description - Version 1.2: 2024-11-20
Changes: Structure summary
