Download MendeleyThe 0.86 angstrom X-ray structure of the human heart fatty acid-binding protein complexed with heptadecanoic acid
Sugiyama, S., Kakinouchi, K., Matsuoka, S., Tsuchikawa, H., Sonoyama, M., Inoue, Y., Hayashi, F., Murata, M.To be published.
7FDU
The 0.86 angstrom X-ray structure of the human heart fatty acid-binding protein complexed with heptadecanoic acid
- PDB DOI: https://doi.org/10.2210/pdb7FDU/pdb
- Classification: LIPID BINDING PROTEIN
- Organism(s): Homo sapiens
- Expression System: Escherichia coli
- Mutation(s): No
- Deposited: 2021-07-18 Released: 2022-07-20
- Funding Organization(s): Japan Science and Technology, Japan Society for the Promotion of Science (JSPS)
Experimental Data Snapshot
- Method: X-RAY DIFFRACTION
- Resolution: 0.86 Å
- R-Value Free: 0.129
- R-Value Work: 0.120
- R-Value Observed: 0.120
Starting Model: experimental
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This is version 1.1 of the entry. See complete history.
Literature
To be published.
Macromolecules
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 1 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| Fatty acid-binding protein, heart | 133 | Homo sapiens | Mutation(s): 0 Gene Names: FABP3, FABP11, MDGI |  | |
UniProt & NIH Common Fund Data Resources | |||||
Find proteins for P05413 (Homo sapiens) Explore P05413 Go to UniProtKB: P05413 | |||||
PHAROS: P05413 GTEx: ENSG00000121769 | |||||
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
| UniProt Group | P05413 | ||||
Sequence AnnotationsExpand | |||||
| |||||
Small Molecules
| Ligands 2 Unique | |||||
|---|---|---|---|---|---|
| ID | Chains | Name / Formula / InChI Key | 2D Diagram | 3D Interactions | |
| P6G (Subject of Investigation/LOI) Query on P6G | C [auth A], D [auth A] | HEXAETHYLENE GLYCOL C12 H26 O7 IIRDTKBZINWQAW-UHFFFAOYSA-N |  | ||
| X90 (Subject of Investigation/LOI) Query on X90 | B [auth A] | heptadecanoic acid C17 H34 O2 KEMQGTRYUADPNZ-UHFFFAOYSA-N |  | ||
Experimental Data & Validation
Experimental Data
- Method: X-RAY DIFFRACTION
- Resolution: 0.86 Å
- R-Value Free: 0.129
- R-Value Work: 0.120
- R-Value Observed: 0.120
- Space Group: P 21 21 21
Unit Cell:
| Length ( Å ) | Angle ( ˚ ) |
|---|---|
| a = 54.655 | α = 90 |
| b = 69.82 | β = 90 |
| c = 33.737 | γ = 90 |
| Software Name | Purpose |
|---|---|
| REFMAC | refinement |
| HKL-2000 | data reduction |
| HKL-2000 | data scaling |
| MOLREP | phasing |
Entry History & Funding Information
Deposition Data
- Released Date: 2022-07-20 Deposition Author(s): Sugiyama, S., Kakinouchi, K., Matsuoka, S., Tsuchikawa, H., Sonoyama, M., Inoue, Y., Hayashi, F., Murata, M.
| Funding Organization | Location | Grant Number |
|---|---|---|
| Japan Science and Technology | Japan | JPMJTM19DC |
| Japan Society for the Promotion of Science (JSPS) | Japan | 19K06588 |
| Japan Science and Technology | Japan | JPMJER1005 |
Revision History (Full details and data files)
- Version 1.0: 2022-07-20
Type: Initial release - Version 1.1: 2023-11-29
Changes: Data collection, Refinement description
