Download MendeleyCrystal Structure of UDP-glucose 4-epimerase (Rv3634c) co-crystallized with UDP-N-acetylgalactosamine from Mycobacterium tuberculosis
Yadav, S., Bhatia, I., Biswal, B.K.To be published.
7YSY
Crystal Structure of UDP-glucose 4-epimerase (Rv3634c) co-crystallized with UDP-N-acetylgalactosamine from Mycobacterium tuberculosis
- PDB DOI: https://doi.org/10.2210/pdb7YSY/pdb
- Classification: ISOMERASE
- Organism(s): Mycobacterium tuberculosis H37Rv
- Expression System: Mycolicibacterium smegmatis
- Mutation(s): No
- Deposited: 2022-08-13 Released: 2023-08-16
- Funding Organization(s): Indian Council of Medical Research
Experimental Data Snapshot
- Method: X-RAY DIFFRACTION
- Resolution: 2.16 Å
- R-Value Free: 0.218
- R-Value Work: 0.158
- R-Value Observed: 0.161
This is version 1.0 of the entry. See complete history.
Literature
To be published.
Macromolecules
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 1 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| UDP-glucose 4-epimerase | 320 | Mycobacterium tuberculosis H37Rv | Mutation(s): 0 Gene Names: galE1, Rv3634c EC: 5.1.3.2 |  | |
UniProt | |||||
Find proteins for P9WN67 (Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)) Explore P9WN67 Go to UniProtKB: P9WN67 | |||||
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
| UniProt Group | P9WN67 | ||||
Sequence AnnotationsExpand | |||||
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Small Molecules
| Ligands 3 Unique | |||||
|---|---|---|---|---|---|
| ID | Chains | Name / Formula / InChI Key | 2D Diagram | 3D Interactions | |
| NAD (Subject of Investigation/LOI) Query on NAD | C [auth A], E [auth B] | NICOTINAMIDE-ADENINE-DINUCLEOTIDE C21 H27 N7 O14 P2 BAWFJGJZGIEFAR-NNYOXOHSSA-N |  | ||
| UD2 (Subject of Investigation/LOI) Query on UD2 | D [auth A], F [auth B] | URIDINE-DIPHOSPHATE-N-ACETYLGALACTOSAMINE C17 H27 N3 O17 P2 LFTYTUAZOPRMMI-NESSUJCYSA-N |  | ||
| EDO (Subject of Investigation/LOI) Query on EDO | G [auth B] | 1,2-ETHANEDIOL C2 H6 O2 LYCAIKOWRPUZTN-UHFFFAOYSA-N |  | ||
Experimental Data & Validation
Experimental Data
- Method: X-RAY DIFFRACTION
- Resolution: 2.16 Å
- R-Value Free: 0.218
- R-Value Work: 0.158
- R-Value Observed: 0.161
- Space Group: P 1 21 1
Unit Cell:
| Length ( Å ) | Angle ( ˚ ) |
|---|---|
| a = 51.166 | α = 90 |
| b = 76.342 | β = 91.8 |
| c = 80.023 | γ = 90 |
| Software Name | Purpose |
|---|---|
| HKL-2000 | data reduction |
| SCALEPACK | data scaling |
| PHASER | phasing |
| REFMAC | refinement |
| PDB_EXTRACT | data extraction |
Entry History & Funding Information
Deposition Data
- Released Date: 2023-08-16 Deposition Author(s): Yadav, S., Bhatia, I., Biswal, B.K.
| Funding Organization | Location | Grant Number |
|---|---|---|
| Indian Council of Medical Research | India | R.12014/03/2019-HR |
Revision History (Full details and data files)
- Version 1.0: 2023-08-16
Type: Initial release
