9DFD

Crystal structure of the wild-type Thermus thermophilus 70S ribosome in complex with lasso peptide lariocidin B, mRNA, aminoacylated A-site Phe-tRNAphe, aminoacylated P-site fMet-tRNAmet, and deacylated E-site tRNAphe at 2.60A resolution

Experimental Data Snapshot

  • Method: X-RAY DIFFRACTION
  • Resolution: 2.60 Å
  • R-Value Free: 0.266 
  • R-Value Work: 0.215 
  • R-Value Observed: 0.217 

wwPDB Validation   3D Report Full Report


This is version 1.0 of the entry. See complete history. 


Literature

A Broad Spectrum Lasso Peptide Antibiotic Targeting the Bacterial Ribosome.

Wright, G., Jangra, M., Travin, D., Aleksandrova, E., Kaur, M., Darwish, L., Koteva, K., Klepacki, D., Wang, W., Tiffany, M., Sokaribo, A., Coombes, B., Vazquez-Laslop, N., Polikanov, Y., Mankin, A.

(2024) Res Sq 

  • DOI: https://doi.org/10.21203/rs.3.rs-5058118/v1
  • Primary Citation of Related Structures:  
    9DFC, 9DFD, 9DFE

  • PubMed Abstract: 

    Lasso peptides, biologically active molecules with a distinct structurally constrained knotted fold, are natural products belonging to the class of ribosomally-synthesized and posttranslationally modified peptides (RiPPs). Lasso peptides act upon several bacterial targets, but none have been reported to inhibit the ribosome, one of the main antibiotic targets in the bacterial cell. Here, we report the identification and characterization of the lasso peptide antibiotic, lariocidin (LAR), and its internally cyclized derivative, lariocidin B (LAR-B), produced by Paenabacillussp . M2, with broad-spectrum activity against many bacterial pathogens. We show that lariocidins inhibit bacterial growth by binding to the ribosome and interfering with protein synthesis. Structural, genetic, and biochemical data show that lariocidins bind at a unique site in the small ribosomal subunit, where they interact with the 16S rRNA and aminoacyl-tRNA, inhibiting translocation and inducing miscoding. LAR is unaffected by common resistance mechanisms, has a low propensity for generating spontaneous resistance, shows no human cell toxicity, and has potent in vivo activity in a mouse model of Acinetobacter baumannii infection. Our finding of the first ribosome-targeting lasso peptides uncovers new routes toward discovering alternative protein synthesis inhibitors and offers a new chemical scaffold for developing much-needed antibacterial drugs.

    • Organizational Affiliation: 

    McMaster University.


Macromolecules

Find similar proteins by: 
(by identity cutoff)  |  3D Structure
Entity ID: 3
MoleculeChains Sequence LengthOrganismDetailsImage
50S ribosomal protein L2C [auth 1D],
HB [auth 2D]		276Thermus thermophilus HB8Mutation(s): 0 
UniProt
Find proteins for P60405 (Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8))
Explore P60405 
Go to UniProtKB:  P60405
Entity Groups  
Sequence Clusters30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity
UniProt GroupP60405
Sequence Annotations
Expand
  • Reference Sequence
Find similar proteins by: 
(by identity cutoff)  |  3D Structure
Entity ID: 4
MoleculeChains Sequence LengthOrganismDetailsImage
50S ribosomal protein L3D [auth 1E],
IB [auth 2E]		206Thermus thermophilus HB8Mutation(s): 0 
UniProt
Find proteins for Q5SHN8 (Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8))
Explore Q5SHN8 
Go to UniProtKB:  Q5SHN8
Entity Groups  
Sequence Clusters30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity
UniProt GroupQ5SHN8
Sequence Annotations
Expand
  • Reference Sequence
Find similar proteins by: 
(by identity cutoff)  |  3D Structure
Entity ID: 5
MoleculeChains Sequence LengthOrganismDetailsImage
50S ribosomal protein L4E [auth 1F],
JB [auth 2F]		210Thermus thermophilus HB8Mutation(s): 0 
UniProt
Find proteins for Q5SHN9 (Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8))
Explore Q5SHN9 
Go to UniProtKB:  Q5SHN9
Entity Groups  
Sequence Clusters30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity
UniProt GroupQ5SHN9
Sequence Annotations
Expand
  • Reference Sequence
Find similar proteins by: 
(by identity cutoff)  |  3D Structure
Entity ID: 6
MoleculeChains Sequence LengthOrganismDetailsImage
50S ribosomal protein L5F [auth 1G],
KB [auth 2G]		182Thermus thermophilus HB8Mutation(s): 0 
UniProt
Find proteins for Q5SHQ0 (Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8))
Explore Q5SHQ0 
Go to UniProtKB:  Q5SHQ0
Entity Groups  
Sequence Clusters30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity
UniProt GroupQ5SHQ0
Sequence Annotations
Expand
  • Reference Sequence
Find similar proteins by: 
(by identity cutoff)  |  3D Structure
Entity ID: 7
MoleculeChains Sequence LengthOrganismDetailsImage
50S ribosomal protein L6G [auth 1H],
LB [auth 2H]		180Thermus thermophilus HB8Mutation(s): 0 
UniProt
Find proteins for P0DOY8 (Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8))
Explore P0DOY8 
Go to UniProtKB:  P0DOY8
Entity Groups  
Sequence Clusters30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity
UniProt GroupP0DOY8
Sequence Annotations
Expand
  • Reference Sequence
Find similar proteins by: 
(by identity cutoff)  |  3D Structure
Entity ID: 8
MoleculeChains Sequence LengthOrganismDetailsImage
50S ribosomal protein L9H [auth 1I],
MB [auth 2I]		148Thermus thermophilus HB8Mutation(s): 0 
UniProt
Find proteins for Q5SLQ1 (Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8))
Explore Q5SLQ1 
Go to UniProtKB:  Q5SLQ1
Entity Groups  
Sequence Clusters30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity
UniProt GroupQ5SLQ1
Sequence Annotations
Expand
  • Reference Sequence
Find similar proteins by: 
(by identity cutoff)  |  3D Structure
Entity ID: 9
MoleculeChains Sequence LengthOrganismDetailsImage
50S ribosomal protein L13I [auth 1N],
NB [auth 2N]		140Thermus thermophilus HB8Mutation(s): 0 
UniProt
Find proteins for P60488 (Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8))
Explore P60488 
Go to UniProtKB:  P60488
Entity Groups  
Sequence Clusters30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity
UniProt GroupP60488
Sequence Annotations
Expand
  • Reference Sequence
Find similar proteins by: 
(by identity cutoff)  |  3D Structure
Entity ID: 10
MoleculeChains Sequence LengthOrganismDetailsImage
50S ribosomal protein L14J [auth 1O],
OB [auth 2O]		122Thermus thermophilus HB8Mutation(s): 0 
UniProt
Find proteins for Q5SHP8 (Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8))
Explore Q5SHP8 
Go to UniProtKB:  Q5SHP8
Entity Groups  
Sequence Clusters30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity
UniProt GroupQ5SHP8
Sequence Annotations
Expand
  • Reference Sequence
Find similar proteins by: 
(by identity cutoff)  |  3D Structure
Entity ID: 11
MoleculeChains Sequence LengthOrganismDetailsImage
50S ribosomal protein L15K [auth 1P],
PB [auth 2P]		150Thermus thermophilus HB8Mutation(s): 0 
UniProt
Find proteins for Q5SHQ7 (Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8))
Explore Q5SHQ7 
Go to UniProtKB:  Q5SHQ7
Entity Groups  
Sequence Clusters30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity
UniProt GroupQ5SHQ7
Sequence Annotations
Expand
  • Reference Sequence
Find similar proteins by: 
(by identity cutoff)  |  3D Structure
Entity ID: 12
MoleculeChains Sequence LengthOrganismDetailsImage
50S ribosomal protein L16L [auth 1Q],
QB [auth 2Q]		141Thermus thermophilus HB8Mutation(s): 0 
UniProt
Find proteins for P60489 (Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8))
Explore P60489 
Go to UniProtKB:  P60489
Entity Groups  
Sequence Clusters30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity
UniProt GroupP60489
Sequence Annotations
Expand
  • Reference Sequence
Find similar proteins by: 
(by identity cutoff)  |  3D Structure
Entity ID: 13
MoleculeChains Sequence LengthOrganismDetailsImage
50S ribosomal protein L17M [auth 1R],
RB [auth 2R]		118Thermus thermophilus HB8Mutation(s): 0 
UniProt
Find proteins for Q9Z9H5 (Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8))
Explore Q9Z9H5 
Go to UniProtKB:  Q9Z9H5
Entity Groups  
Sequence Clusters30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity
UniProt GroupQ9Z9H5
Sequence Annotations
Expand
  • Reference Sequence
Find similar proteins by: 
(by identity cutoff)  |  3D Structure
Entity ID: 14
MoleculeChains Sequence LengthOrganismDetailsImage
50S ribosomal protein L18N [auth 1S],
SB [auth 2S]		112Thermus thermophilus HB8Mutation(s): 0 
UniProt
Find proteins for Q5SHQ4 (Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8))
Explore Q5SHQ4 
Go to UniProtKB:  Q5SHQ4
Entity Groups  
Sequence Clusters30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity
UniProt GroupQ5SHQ4
Sequence Annotations
Expand
  • Reference Sequence
Find similar proteins by: 
(by identity cutoff)  |  3D Structure
Entity ID: 15
MoleculeChains Sequence LengthOrganismDetailsImage
50S ribosomal protein L19O [auth 1T],
TB [auth 2T]		146Thermus thermophilus HB8Mutation(s): 0 
UniProt
Find proteins for P60490 (Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8))
Explore P60490 
Go to UniProtKB:  P60490
Entity Groups  
Sequence Clusters30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity
UniProt GroupP60490
Sequence Annotations
Expand
  • Reference Sequence
Find similar proteins by: 
(by identity cutoff)  |  3D Structure
Entity ID: 16
MoleculeChains Sequence LengthOrganismDetailsImage
50S ribosomal protein L20P [auth 1U],
UB [auth 2U]		118Thermus thermophilus HB8Mutation(s): 0 
UniProt
Find proteins for P60491 (Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8))
Explore P60491 
Go to UniProtKB:  P60491
Entity Groups  
Sequence Clusters30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity
UniProt GroupP60491
Sequence Annotations
Expand
  • Reference Sequence
Find similar proteins by: 
(by identity cutoff)  |  3D Structure
Entity ID: 17
MoleculeChains Sequence LengthOrganismDetailsImage
50S ribosomal protein L21Q [auth 1V],
VB [auth 2V]		101Thermus thermophilus HB8Mutation(s): 0 
UniProt
Find proteins for P60492 (Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8))
Explore P60492 
Go to UniProtKB:  P60492
Entity Groups  
Sequence Clusters30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity
UniProt GroupP60492
Sequence Annotations
Expand
  • Reference Sequence
Find similar proteins by: 
(by identity cutoff)  |  3D Structure
Entity ID: 18
MoleculeChains Sequence LengthOrganismDetailsImage
50S ribosomal protein L22R [auth 1W],
WB [auth 2W]		113Thermus thermophilus HB8Mutation(s): 0 
UniProt
Find proteins for Q5SHP3 (Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8))
Explore Q5SHP3 
Go to UniProtKB:  Q5SHP3
Entity Groups  
Sequence Clusters30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity
UniProt GroupQ5SHP3
Sequence Annotations
Expand
  • Reference Sequence
Find similar proteins by: 
(by identity cutoff)  |  3D Structure
Entity ID: 19
MoleculeChains Sequence LengthOrganismDetailsImage
50S ribosomal protein L23S [auth 1X],
XB [auth 2X]		96Thermus thermophilus HB8Mutation(s): 0 
UniProt
Find proteins for Q5SHP0 (Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8))
Explore Q5SHP0 
Go to UniProtKB:  Q5SHP0
Entity Groups  
Sequence Clusters30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity
UniProt GroupQ5SHP0
Sequence Annotations
Expand
  • Reference Sequence
Find similar proteins by: 
(by identity cutoff)  |  3D Structure
Entity ID: 20
MoleculeChains Sequence LengthOrganismDetailsImage
50S ribosomal protein L24T [auth 1Y],
YB [auth 2Y]		110Thermus thermophilus HB8Mutation(s): 0 
UniProt
Find proteins for Q5SHP9 (Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8))
Explore Q5SHP9 
Go to UniProtKB:  Q5SHP9
Entity Groups  
Sequence Clusters30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity
UniProt GroupQ5SHP9
Sequence Annotations
Expand
  • Reference Sequence
Find similar proteins by: 
(by identity cutoff)  |  3D Structure
Entity ID: 21
MoleculeChains Sequence LengthOrganismDetailsImage
50S ribosomal protein L25U [auth 1Z],
ZB [auth 2Z]		206Thermus thermophilus HB8Mutation(s): 0 
UniProt
Find proteins for Q5SHZ1 (Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8))
Explore Q5SHZ1 
Go to UniProtKB:  Q5SHZ1
Entity Groups  
Sequence Clusters30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity
UniProt GroupQ5SHZ1
Sequence Annotations
Expand
  • Reference Sequence
Find similar proteins by: 
(by identity cutoff)  |  3D Structure
Entity ID: 22
MoleculeChains Sequence LengthOrganismDetailsImage
50S ribosomal protein L27AC [auth 20],
V [auth 10]		85Thermus thermophilus HB8Mutation(s): 0 
UniProt
Find proteins for P60493 (Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8))
Explore P60493 
Go to UniProtKB:  P60493
Entity Groups  
Sequence Clusters30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity
UniProt GroupP60493
Sequence Annotations
Expand
  • Reference Sequence
Find similar proteins by: 
(by identity cutoff)  |  3D Structure
Entity ID: 23
MoleculeChains Sequence LengthOrganismDetailsImage
50S ribosomal protein L28BC [auth 21],
W [auth 11]		98Thermus thermophilus HB8Mutation(s): 0 
UniProt
Find proteins for P60494 (Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8))
Explore P60494 
Go to UniProtKB:  P60494
Entity Groups  
Sequence Clusters30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity
UniProt GroupP60494
Sequence Annotations
Expand
  • Reference Sequence
Find similar proteins by: 
(by identity cutoff)  |  3D Structure
Entity ID: 24
MoleculeChains Sequence LengthOrganismDetailsImage
50S ribosomal protein L29CC [auth 22],
X [auth 12]		72Thermus thermophilus HB8Mutation(s): 0 
UniProt
Find proteins for Q5SHP6 (Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8))
Explore Q5SHP6 
Go to UniProtKB:  Q5SHP6
Entity Groups  
Sequence Clusters30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity
UniProt GroupQ5SHP6
Sequence Annotations
Expand
  • Reference Sequence
Find similar proteins by: 
(by identity cutoff)  |  3D Structure
Entity ID: 25
MoleculeChains Sequence LengthOrganismDetailsImage
50S ribosomal protein L30DC [auth 23],
Y [auth 13]		60Thermus thermophilus HB8Mutation(s): 0 
UniProt
Find proteins for Q5SHQ6 (Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8))
Explore Q5SHQ6 
Go to UniProtKB:  Q5SHQ6
Entity Groups  
Sequence Clusters30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity
UniProt GroupQ5SHQ6
Sequence Annotations
Expand
  • Reference Sequence
Find similar proteins by: 
(by identity cutoff)  |  3D Structure
Entity ID: 26
MoleculeChains Sequence LengthOrganismDetailsImage
50S ribosomal protein L31EC [auth 24],
Z [auth 14]		71Thermus thermophilus HB8Mutation(s): 0 
UniProt
Find proteins for Q5SJE1 (Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8))
Explore Q5SJE1 
Go to UniProtKB:  Q5SJE1
Entity Groups  
Sequence Clusters30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity
UniProt GroupQ5SJE1
Sequence Annotations
Expand
  • Reference Sequence
Find similar proteins by: 
(by identity cutoff)  |  3D Structure
Entity ID: 27
MoleculeChains Sequence LengthOrganismDetailsImage
50S ribosomal protein L32AA [auth 15],
FC [auth 25]		60Thermus thermophilus HB8Mutation(s): 0 
UniProt
Find proteins for P80339 (Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8))
Explore P80339 
Go to UniProtKB:  P80339
Entity Groups  
Sequence Clusters30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity
UniProt GroupP80339
Sequence Annotations
Expand
  • Reference Sequence
Find similar proteins by: 
(by identity cutoff)  |  3D Structure
Entity ID: 28
MoleculeChains Sequence LengthOrganismDetailsImage
50S ribosomal protein L33BA [auth 16],
GC [auth 26]		54Thermus thermophilus HB8Mutation(s): 0 
UniProt
Find proteins for P35871 (Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8))
Explore P35871 
Go to UniProtKB:  P35871
Entity Groups  
Sequence Clusters30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity
UniProt GroupP35871
Sequence Annotations
Expand
  • Reference Sequence
Find similar proteins by: 
(by identity cutoff)  |  3D Structure
Entity ID: 29
MoleculeChains Sequence LengthOrganismDetailsImage
50S ribosomal protein L34CA [auth 17],
HC [auth 27]		49Thermus thermophilus HB8Mutation(s): 0 
UniProt
Find proteins for P80340 (Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8))
Explore P80340 
Go to UniProtKB:  P80340
Entity Groups  
Sequence Clusters30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity
UniProt GroupP80340
Sequence Annotations
Expand
  • Reference Sequence
Find similar proteins by: 
(by identity cutoff)  |  3D Structure
Entity ID: 30
MoleculeChains Sequence LengthOrganismDetailsImage
50S ribosomal protein L35DA [auth 18],
IC [auth 28]		65Thermus thermophilus HB8Mutation(s): 0 
UniProt
Find proteins for Q5SKU1 (Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8))
Explore Q5SKU1 
Go to UniProtKB:  Q5SKU1
Entity Groups  
Sequence Clusters30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity
UniProt GroupQ5SKU1
Sequence Annotations
Expand
  • Reference Sequence
Find similar proteins by: 
(by identity cutoff)  |  3D Structure
Entity ID: 31
MoleculeChains Sequence LengthOrganismDetailsImage
50S ribosomal protein L36EA [auth 19],
JC [auth 29]		37Thermus thermophilus HB8Mutation(s): 0 
UniProt
Find proteins for Q5SHR2 (Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8))
Explore Q5SHR2 
Go to UniProtKB:  Q5SHR2
Entity Groups  
Sequence Clusters30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity
UniProt GroupQ5SHR2
Sequence Annotations
Expand
  • Reference Sequence
Find similar proteins by: 
(by identity cutoff)  |  3D Structure
Entity ID: 33
MoleculeChains Sequence LengthOrganismDetailsImage
30S ribosomal protein S2GA [auth 1b],
LC [auth 2b]		256Thermus thermophilus HB8Mutation(s): 0 
UniProt
Find proteins for P80371 (Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8))
Explore P80371 
Go to UniProtKB:  P80371
Entity Groups  
Sequence Clusters30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity
UniProt GroupP80371
Sequence Annotations
Expand
  • Reference Sequence
Find similar proteins by: 
(by identity cutoff)  |  3D Structure
Entity ID: 34
MoleculeChains Sequence LengthOrganismDetailsImage
30S ribosomal protein S3HA [auth 1c],
MC [auth 2c]		239Thermus thermophilus HB8Mutation(s): 0 
UniProt
Find proteins for P80372 (Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8))
Explore P80372 
Go to UniProtKB:  P80372
Entity Groups  
Sequence Clusters30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity
UniProt GroupP80372
Sequence Annotations
Expand
  • Reference Sequence
Find similar proteins by: 
(by identity cutoff)  |  3D Structure
Entity ID: 35
MoleculeChains Sequence LengthOrganismDetailsImage
30S ribosomal protein S4IA [auth 1d],
NC [auth 2d]		209Thermus thermophilus HB8Mutation(s): 0 
UniProt
Find proteins for P80373 (Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8))
Explore P80373 
Go to UniProtKB:  P80373
Entity Groups  
Sequence Clusters30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity
UniProt GroupP80373
Sequence Annotations
Expand
  • Reference Sequence
Find similar proteins by: 
(by identity cutoff)  |  3D Structure
Entity ID: 36
MoleculeChains Sequence LengthOrganismDetailsImage
30S ribosomal protein S5JA [auth 1e],
OC [auth 2e]		162Thermus thermophilus HB8Mutation(s): 0 
UniProt
Find proteins for Q5SHQ5 (Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8))
Explore Q5SHQ5 
Go to UniProtKB:  Q5SHQ5
Entity Groups  
Sequence Clusters30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity
UniProt GroupQ5SHQ5
Sequence Annotations
Expand
  • Reference Sequence
Find similar proteins by: 
(by identity cutoff)  |  3D Structure
Entity ID: 37
MoleculeChains Sequence LengthOrganismDetailsImage
30S ribosomal protein S6KA [auth 1f],
PC [auth 2f]		101Thermus thermophilus HB8Mutation(s): 0 
UniProt
Find proteins for Q5SLP8 (Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8))
Explore Q5SLP8 
Go to UniProtKB:  Q5SLP8
Entity Groups  
Sequence Clusters30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity
UniProt GroupQ5SLP8
Sequence Annotations
Expand
  • Reference Sequence
Find similar proteins by: 
(by identity cutoff)  |  3D Structure
Entity ID: 38
MoleculeChains Sequence LengthOrganismDetailsImage
30S ribosomal protein S7LA [auth 1g],
QC [auth 2g]		156Thermus thermophilus HB8Mutation(s): 0 
UniProt
Find proteins for P17291 (Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8))
Explore P17291 
Go to UniProtKB:  P17291
Entity Groups  
Sequence Clusters30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity
UniProt GroupP17291
Sequence Annotations
Expand
  • Reference Sequence
Find similar proteins by: 
(by identity cutoff)  |  3D Structure
Entity ID: 39
MoleculeChains Sequence LengthOrganismDetailsImage
30S ribosomal protein S8MA [auth 1h],
RC [auth 2h]		138Thermus thermophilus HB8Mutation(s): 0 
UniProt
Find proteins for P0DOY9 (Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8))
Explore P0DOY9 
Go to UniProtKB:  P0DOY9
Entity Groups  
Sequence Clusters30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity
UniProt GroupP0DOY9
Sequence Annotations
Expand
  • Reference Sequence
Find similar proteins by: 
(by identity cutoff)  |  3D Structure
Entity ID: 40
MoleculeChains Sequence LengthOrganismDetailsImage
30S ribosomal protein S9NA [auth 1i],
SC [auth 2i]		128Thermus thermophilus HB8Mutation(s): 0 
UniProt
Find proteins for P80374 (Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8))
Explore P80374 
Go to UniProtKB:  P80374
Entity Groups  
Sequence Clusters30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity
UniProt GroupP80374
Sequence Annotations
Expand
  • Reference Sequence
Find similar proteins by: 
(by identity cutoff)  |  3D Structure
Entity ID: 41
MoleculeChains Sequence LengthOrganismDetailsImage
30S ribosomal protein S10OA [auth 1j],
TC [auth 2j]		105Thermus thermophilus HB8Mutation(s): 0 
UniProt
Find proteins for Q5SHN7 (Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8))
Explore Q5SHN7 
Go to UniProtKB:  Q5SHN7
Entity Groups  
Sequence Clusters30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity
UniProt GroupQ5SHN7
Sequence Annotations
Expand
  • Reference Sequence
Find similar proteins by: 
(by identity cutoff)  |  3D Structure
Entity ID: 42
MoleculeChains Sequence LengthOrganismDetailsImage
30S ribosomal protein S11PA [auth 1k],
UC [auth 2k]		129Thermus thermophilus HB8Mutation(s): 0 
UniProt
Find proteins for P80376 (Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8))
Explore P80376 
Go to UniProtKB:  P80376
Entity Groups  
Sequence Clusters30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity
UniProt GroupP80376
Sequence Annotations
Expand
  • Reference Sequence
Find similar proteins by: 
(by identity cutoff)  |  3D Structure
Entity ID: 43
MoleculeChains Sequence LengthOrganismDetailsImage
30S ribosomal protein S12QA [auth 1l],
VC [auth 2l]		132Thermus thermophilus HB8Mutation(s): 0 
UniProt
Find proteins for Q5SHN3 (Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8))
Explore Q5SHN3 
Go to UniProtKB:  Q5SHN3
Entity Groups  
Sequence Clusters30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity
UniProt GroupQ5SHN3
Sequence Annotations
Expand
  • Reference Sequence
Find similar proteins by: 
(by identity cutoff)  |  3D Structure
Entity ID: 44
MoleculeChains Sequence LengthOrganismDetailsImage
30S ribosomal protein S13RA [auth 1m],
WC [auth 2m]		126Thermus thermophilus HB8Mutation(s): 0 
UniProt
Find proteins for P80377 (Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8))
Explore P80377 
Go to UniProtKB:  P80377
Entity Groups  
Sequence Clusters30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity
UniProt GroupP80377
Sequence Annotations
Expand
  • Reference Sequence
Find similar proteins by: 
(by identity cutoff)  |  3D Structure
Entity ID: 45
MoleculeChains Sequence LengthOrganismDetailsImage
30S ribosomal protein S14 type ZSA [auth 1n],
XC [auth 2n]		61Thermus thermophilus HB8Mutation(s): 0 
UniProt
Find proteins for P0DOY6 (Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8))
Explore P0DOY6 
Go to UniProtKB:  P0DOY6
Entity Groups  
Sequence Clusters30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity
UniProt GroupP0DOY6
Sequence Annotations
Expand
  • Reference Sequence
Find similar proteins by: 
(by identity cutoff)  |  3D Structure
Entity ID: 46
MoleculeChains Sequence LengthOrganismDetailsImage
30S ribosomal protein S15TA [auth 1o],
YC [auth 2o]		89Thermus thermophilus HB8Mutation(s): 0 
UniProt
Find proteins for Q5SJ76 (Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8))
Explore Q5SJ76 
Go to UniProtKB:  Q5SJ76
Entity Groups  
Sequence Clusters30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity
UniProt GroupQ5SJ76
Sequence Annotations
Expand
  • Reference Sequence
Find similar proteins by: 
(by identity cutoff)  |  3D Structure
Entity ID: 47
MoleculeChains Sequence LengthOrganismDetailsImage
30S ribosomal protein S16UA [auth 1p],
ZC [auth 2p]		88Thermus thermophilus HB8Mutation(s): 0 
UniProt
Find proteins for Q5SJH3 (Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8))
Explore Q5SJH3 
Go to UniProtKB:  Q5SJH3
Entity Groups  
Sequence Clusters30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity
UniProt GroupQ5SJH3
Sequence Annotations
Expand
  • Reference Sequence
Find similar proteins by: 
(by identity cutoff)  |  3D Structure
Entity ID: 48
MoleculeChains Sequence LengthOrganismDetailsImage
30S ribosomal protein S17AD [auth 2q],
VA [auth 1q]		105Thermus thermophilus HB8Mutation(s): 0 
UniProt
Find proteins for P0DOY7 (Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8))
Explore P0DOY7 
Go to UniProtKB:  P0DOY7
Entity Groups  
Sequence Clusters30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity
UniProt GroupP0DOY7
Sequence Annotations
Expand
  • Reference Sequence
Find similar proteins by: 
(by identity cutoff)  |  3D Structure
Entity ID: 49
MoleculeChains Sequence LengthOrganismDetailsImage
30S ribosomal protein S18BD [auth 2r],
WA [auth 1r]		88Thermus thermophilus HB8Mutation(s): 0 
UniProt
Find proteins for Q5SLQ0 (Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8))
Explore Q5SLQ0 
Go to UniProtKB:  Q5SLQ0
Entity Groups  
Sequence Clusters30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity
UniProt GroupQ5SLQ0
Sequence Annotations
Expand
  • Reference Sequence
Find similar proteins by: 
(by identity cutoff)  |  3D Structure
Entity ID: 50
MoleculeChains Sequence LengthOrganismDetailsImage
30S ribosomal protein S19CD [auth 2s],
XA [auth 1s]		93Thermus thermophilus HB8Mutation(s): 0 
UniProt
Find proteins for Q5SHP2 (Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8))
Explore Q5SHP2 
Go to UniProtKB:  Q5SHP2
Entity Groups  
Sequence Clusters30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity
UniProt GroupQ5SHP2
Sequence Annotations
Expand
  • Reference Sequence
Find similar proteins by: 
(by identity cutoff)  |  3D Structure
Entity ID: 51
MoleculeChains Sequence LengthOrganismDetailsImage
30S ribosomal protein S20DD [auth 2t],
YA [auth 1t]		106Thermus thermophilus HB8Mutation(s): 0 
UniProt
Find proteins for P80380 (Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8))
Explore P80380 
Go to UniProtKB:  P80380
Entity Groups  
Sequence Clusters30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity
UniProt GroupP80380
Sequence Annotations
Expand
  • Reference Sequence
Find similar proteins by: 
(by identity cutoff)  |  3D Structure
Entity ID: 52
MoleculeChains Sequence LengthOrganismDetailsImage
30S ribosomal protein ThxED [auth 2u],
ZA [auth 1u]		27Thermus thermophilus HB8Mutation(s): 0 
UniProt
Find proteins for Q5SIH3 (Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8))
Explore Q5SIH3 
Go to UniProtKB:  Q5SIH3
Entity Groups  
Sequence Clusters30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity
UniProt GroupQ5SIH3
Sequence Annotations
Expand
  • Reference Sequence

Find similar proteins by:  Sequence   |   3D Structure  

Entity ID: 57
MoleculeChains Sequence LengthOrganismDetailsImage
Lasso peptide lariocidin BEB [auth 1z],
JD [auth 2z]		17PaenibacillusMutation(s): 0 
Entity Groups  
Sequence Clusters30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity
Sequence Annotations
Expand
  • Reference Sequence
Find similar nucleic acids by: 
(by identity cutoff)  |  3D Structure
Entity ID: 1
MoleculeChains LengthOrganismImage
23S Ribosomal RNAA [auth 1A],
FB [auth 2A]		2,915Thermus thermophilus HB8
Sequence Annotations
Expand
  • Reference Sequence
Find similar nucleic acids by: 
(by identity cutoff)  |  3D Structure
Entity ID: 2
MoleculeChains LengthOrganismImage
5S Ribosomal RNAB [auth 1B],
GB [auth 2B]		121Thermus thermophilus HB8
Sequence Annotations
Expand
  • Reference Sequence
Find similar nucleic acids by: 
(by identity cutoff)  |  3D Structure
Entity ID: 32
MoleculeChains LengthOrganismImage
16S Ribosomal RNAFA [auth 1a],
KC [auth 2a]		1,521Thermus thermophilus HB8
Sequence Annotations
Expand
  • Reference Sequence

Find similar nucleic acids by:  Sequence   |   3D Structure  

Entity ID: 53
MoleculeChains LengthOrganismImage
MET-PHE-mRNAAB [auth 1v],
FD [auth 2v]		24Tequatrovirus T4
Sequence Annotations
Expand
  • Reference Sequence
Find similar nucleic acids by: 
(by identity cutoff)  |  3D Structure
Entity ID: 54
MoleculeChains LengthOrganismImage
A-site Aminoacylated Phe-tRNApheBB [auth 1w],
GD [auth 2w]		76Escherichia coli
Sequence Annotations
Expand
  • Reference Sequence
Find similar nucleic acids by: 
(by identity cutoff)  |  3D Structure
Entity ID: 55
MoleculeChains LengthOrganismImage
P-site Aminoacylated fMet-tRNAmetCB [auth 1x],
HD [auth 2x]		77Escherichia coli
Sequence Annotations
Expand
  • Reference Sequence
Find similar nucleic acids by: 
(by identity cutoff)  |  3D Structure
Entity ID: 56
MoleculeChains LengthOrganismImage
E-site Deacylated tRNApheDB [auth 1y],
ID [auth 2y]		76Escherichia coli
Sequence Annotations
Expand
  • Reference Sequence
Small Molecules
Ligands 4 Unique
IDChains Name / Formula / InChI Key2D Diagram3D Interactions
SF4
Query on SF4
Download Ideal Coordinates CCD File 
AKB [auth 1d],
DGD [auth 2d]		IRON/SULFUR CLUSTER
Fe4 S4
LJBDFODJNLIPKO-UHFFFAOYSA-N
ZN
Query on ZN
Download Ideal Coordinates CCD File 
ABB [auth 15]
DBB [auth 16]
DWC [auth 24]
IWC [auth 25]
KKB [auth 1n]
ABB [auth 15],
DBB [auth 16],
DWC [auth 24],
IWC [auth 25],
KKB [auth 1n],
KWC [auth 26],
NBB [auth 19],
PGD [auth 2n],
QAB [auth 14],
SZA [auth 1Y],
TWC [auth 29],
ZVC [auth 2Y]
ZINC ION
Zn
PTFCDOFLOPIGGS-UHFFFAOYSA-N
K
Query on K
Download Ideal Coordinates CCD File 
GZ [auth 1A],
KHD [auth 2x]		POTASSIUM ION
K
NPYPAHLBTDXSSS-UHFFFAOYSA-N
MG
Query on MG
Download Ideal Coordinates CCD File 
AAA [auth 1A]
AAB [auth 10]
AAC [auth 2A]
AAD [auth 2a]
ABA [auth 1A]
AAA [auth 1A],
AAB [auth 10],
AAC [auth 2A],
AAD [auth 2a],
ABA [auth 1A],
ABC [auth 2A],
ABD [auth 2a],
ACA [auth 1A],
ACB [auth 1a],
ACC [auth 2A],
ACD [auth 2a],
ADA [auth 1A],
ADB [auth 1a],
ADC [auth 2A],
ADD [auth 2a],
AE [auth 1A],
AEA [auth 1A],
AEB [auth 1a],
AEC [auth 2A],
AED [auth 2a],
AF [auth 1A],
AFA [auth 1A],
AFB [auth 1a],
AFC [auth 2A],
AFD [auth 2a],
AG [auth 1A],
AGA [auth 1A],
AGB [auth 1a],
AGC [auth 2A],
AGD [auth 2a],
AH [auth 1A],
AHA [auth 1A],
AHB [auth 1a],
AHC [auth 2A],
AHD [auth 2w],
AI [auth 1A],
AIA [auth 1A],
AIB [auth 1a],
AIC [auth 2A],
AJ [auth 1A],
AJA [auth 1A],
AJB [auth 1a],
AJC [auth 2A],
AK [auth 1A],
AKA [auth 1A],
AKC [auth 2A],
AL [auth 1A],
ALA [auth 1A],
ALB [auth 1x],
ALC [auth 2A],
AM [auth 1A],
AMA [auth 1A],
AMB [auth 2A],
AMC [auth 2A],
AN [auth 1A],
ANA [auth 1A],
ANB [auth 2A],
ANC [auth 2A],
AO [auth 1A],
AOA [auth 1A],
AOB [auth 2A],
AOC [auth 2A],
AP [auth 1A],
APA [auth 1A],
APB [auth 2A],
APC [auth 2A],
AQ [auth 1A],
AQA [auth 1A],
AQB [auth 2A],
AQC [auth 2A],
AR [auth 1A],
ARA [auth 1A],
ARB [auth 2A],
ARC [auth 2A],
AS [auth 1A],
ASA [auth 1A],
ASB [auth 2A],
ASC [auth 2A],
AT [auth 1A],
ATA [auth 1A],
ATB [auth 2A],
ATC [auth 2A],
AU [auth 1A],
AUA [auth 1B],
AUB [auth 2A],
AUC [auth 2B],
AV [auth 1A],
AVA [auth 1B],
AVB [auth 2A],
AVC [auth 2F],
AW [auth 1A],
AWA [auth 1E],
AWB [auth 2A],
AWC [auth 2Z],
AX [auth 1A],
AXA [auth 1G],
AXB [auth 2A],
AXC [auth 2a],
AY [auth 1A],
AYA [auth 1R],
AYB [auth 2A],
AYC [auth 2a],
AZ [auth 1A],
AZA [auth 1V],
AZB [auth 2A],
AZC [auth 2a],
BAA [auth 1A],
BAB [auth 10],
BAC [auth 2A],
BAD [auth 2a],
BBA [auth 1A],
BBB [auth 16],
BBC [auth 2A],
BBD [auth 2a],
BCA [auth 1A],
BCB [auth 1a],
BCC [auth 2A],
BCD [auth 2a],
BDA [auth 1A],
BDB [auth 1a],
BDC [auth 2A],
BDD [auth 2a],
BE [auth 1A],
BEA [auth 1A],
BEB [auth 1a],
BEC [auth 2A],
BED [auth 2a],
BF [auth 1A],
BFA [auth 1A],
BFB [auth 1a],
BFC [auth 2A],
BFD [auth 2a],
BG [auth 1A],
BGA [auth 1A],
BGB [auth 1a],
BGC [auth 2A],
BGD [auth 2a],
BH [auth 1A],
BHA [auth 1A],
BHB [auth 1a],
BHC [auth 2A],
BHD [auth 2w],
BI [auth 1A],
BIA [auth 1A],
BIB [auth 1a],
BIC [auth 2A],
BJ [auth 1A],
BJA [auth 1A],
BJB [auth 1a],
BJC [auth 2A],
BK [auth 1A],
BKA [auth 1A],
BKB [auth 1e],
BKC [auth 2A],
BL [auth 1A],
BLA [auth 1A],
BLB [auth 1x],
BLC [auth 2A],
BM [auth 1A],
BMA [auth 1A],
BMB [auth 2A],
BMC [auth 2A],
BN [auth 1A],
BNA [auth 1A],
BNB [auth 2A],
BNC [auth 2A],
BO [auth 1A],
BOA [auth 1A],
BOB [auth 2A],
BOC [auth 2A],
BP [auth 1A],
BPA [auth 1A],
BPB [auth 2A],
BPC [auth 2A],
BQ [auth 1A],
BQA [auth 1A],
BQB [auth 2A],
BQC [auth 2A],
BR [auth 1A],
BRA [auth 1A],
BRB [auth 2A],
BRC [auth 2A],
BS [auth 1A],
BSA [auth 1A],
BSB [auth 2A],
BSC [auth 2A],
BT [auth 1A],
BTA [auth 1A],
BTB [auth 2A],
BTC [auth 2A],
BU [auth 1A],
BUA [auth 1B],
BUB [auth 2A],
BUC [auth 2B],
BV [auth 1A],
BVA [auth 1B],
BVB [auth 2A],
BVC [auth 2F],
BW [auth 1A],
BWA [auth 1E],
BWB [auth 2A],
BWC [auth 21],
BX [auth 1A],
BXA [auth 1I],
BXB [auth 2A],
BXC [auth 2a],
BY [auth 1A],
BYA [auth 1R],
BYB [auth 2A],
BYC [auth 2a],
BZ [auth 1A],
BZA [auth 1W],
BZB [auth 2A],
BZC [auth 2a],
CAA [auth 1A],
CAB [auth 10],
CAC [auth 2A],
CAD [auth 2a],
CBA [auth 1A],
CBB [auth 16],
CBC [auth 2A],
CBD [auth 2a],
CCA [auth 1A],
CCB [auth 1a],
CCC [auth 2A],
CCD [auth 2a],
CDA [auth 1A],
CDB [auth 1a],
CDC [auth 2A],
CDD [auth 2a],
CE [auth 1A],
CEA [auth 1A],
CEB [auth 1a],
CEC [auth 2A],
CED [auth 2a],
CF [auth 1A],
CFA [auth 1A],
CFB [auth 1a],
CFC [auth 2A],
CFD [auth 2a],
CG [auth 1A],
CGA [auth 1A],
CGB [auth 1a],
CGC [auth 2A],
CGD [auth 2d],
CH [auth 1A],
CHA [auth 1A],
CHB [auth 1a],
CHC [auth 2A],
CHD [auth 2w],
CI [auth 1A],
CIA [auth 1A],
CIB [auth 1a],
CIC [auth 2A],
CJ [auth 1A],
CJA [auth 1A],
CJB [auth 1a],
CJC [auth 2A],
CK [auth 1A],
CKA [auth 1A],
CKB [auth 1e],
CKC [auth 2A],
CL [auth 1A],
CLA [auth 1A],
CLB [auth 1x],
CLC [auth 2A],
CM [auth 1A],
CMA [auth 1A],
CMB [auth 2A],
CMC [auth 2A],
CN [auth 1A],
CNA [auth 1A],
CNB [auth 2A],
CNC [auth 2A],
CO [auth 1A],
COA [auth 1A],
COB [auth 2A],
COC [auth 2A],
CP [auth 1A],
CPA [auth 1A],
CPB [auth 2A],
CPC [auth 2A],
CQ [auth 1A],
CQA [auth 1A],
CQB [auth 2A],
CQC [auth 2A],
CR [auth 1A],
CRA [auth 1A],
CRB [auth 2A],
CRC [auth 2A],
CS [auth 1A],
CSA [auth 1A],
CSB [auth 2A],
CSC [auth 2A],
CT [auth 1A],
CTA [auth 1A],
CTB [auth 2A],
CTC [auth 2A],
CU [auth 1A],
CUA [auth 1B],
CUB [auth 2A],
CUC [auth 2B],
CV [auth 1A],
CVA [auth 1B],
CVB [auth 2A],
CVC [auth 2F],
CW [auth 1A],
CWA [auth 1E],
CWB [auth 2A],
CWC [auth 23],
CX [auth 1A],
CXA [auth 1N],
CXB [auth 2A],
CXC [auth 2a],
CY [auth 1A],
CYA [auth 1R],
CYB [auth 2A],
CYC [auth 2a],
CZ [auth 1A],
CZA [auth 1W],
CZB [auth 2A],
CZC [auth 2a],
DAA [auth 1A],
DAB [auth 10],
DAC [auth 2A],
DAD [auth 2a],
DBA [auth 1A],
DBC [auth 2A],
DBD [auth 2a],
DCA [auth 1A],
DCB [auth 1a],
DCC [auth 2A],
DCD [auth 2a],
DDA [auth 1A],
DDB [auth 1a],
DDC [auth 2A],
DDD [auth 2a],
DE [auth 1A],
DEA [auth 1A],
DEB [auth 1a],
DEC [auth 2A],
DED [auth 2a],
DF [auth 1A],
DFA [auth 1A],
DFB [auth 1a],
DFC [auth 2A],
DFD [auth 2a],
DG [auth 1A],
DGA [auth 1A],
DGB [auth 1a],
DGC [auth 2A],
DH [auth 1A],
DHA [auth 1A],
DHB [auth 1a],
DHC [auth 2A],
DHD [auth 2w],
DI [auth 1A],
DIA [auth 1A],
DIB [auth 1a],
DIC [auth 2A],
DJ [auth 1A],
DJA [auth 1A],
DJB [auth 1a],
DJC [auth 2A],
DK [auth 1A],
DKA [auth 1A],
DKB [auth 1f],
DKC [auth 2A],
DL [auth 1A],
DLA [auth 1A],
DLB [auth 1x],
DLC [auth 2A],
DM [auth 1A],
DMA [auth 1A],
DMB [auth 2A],
DMC [auth 2A],
DN [auth 1A],
DNA [auth 1A],
DNB [auth 2A],
DNC [auth 2A],
DO [auth 1A],
DOA [auth 1A],
DOB [auth 2A],
DOC [auth 2A],
DP [auth 1A],
DPA [auth 1A],
DPB [auth 2A],
DPC [auth 2A],
DQ [auth 1A],
DQA [auth 1A],
DQB [auth 2A],
DQC [auth 2A],
DR [auth 1A],
DRA [auth 1A],
DRB [auth 2A],
DRC [auth 2A],
DS [auth 1A],
DSA [auth 1A],
DSB [auth 2A],
DSC [auth 2A],
DT [auth 1A],
DTA [auth 1A],
DTB [auth 2A],
DTC [auth 2A],
DU [auth 1A],
DUA [auth 1B],
DUB [auth 2A],
DUC [auth 2B],
DV [auth 1A],
DVA [auth 1B],
DVB [auth 2A],
DVC [auth 2F],
DW [auth 1A],
DWA [auth 1E],
DWB [auth 2A],
DX [auth 1A],
DXA [auth 1N],
DXB [auth 2A],
DXC [auth 2a],
DY [auth 1A],
DYA [auth 1S],
DYB [auth 2A],
DYC [auth 2a],
DZ [auth 1A],
DZA [auth 1W],
DZB [auth 2A],
DZC [auth 2a],
EAA [auth 1A],
EAB [auth 10],
EAC [auth 2A],
EAD [auth 2a],
EBA [auth 1A],
EBB [auth 17],
EBC [auth 2A],
EBD [auth 2a],
ECA [auth 1A],
ECB [auth 1a],
ECC [auth 2A],
ECD [auth 2a],
EDA [auth 1A],
EDB [auth 1a],
EDC [auth 2A],
EDD [auth 2a],
EE [auth 1A],
EEA [auth 1A],
EEB [auth 1a],
EEC [auth 2A],
EED [auth 2a],
EF [auth 1A],
EFA [auth 1A],
EFB [auth 1a],
EFC [auth 2A],
EFD [auth 2a],
EG [auth 1A],
EGA [auth 1A],
EGB [auth 1a],
EGC [auth 2A],
EGD [auth 2e],
EH [auth 1A],
EHA [auth 1A],
EHB [auth 1a],
EHC [auth 2A],
EHD [auth 2w],
EI [auth 1A],
EIA [auth 1A],
EIB [auth 1a],
EIC [auth 2A],
EJ [auth 1A],
EJA [auth 1A],
EJB [auth 1a],
EJC [auth 2A],
EK [auth 1A],
EKA [auth 1A],
EKB [auth 1f],
EKC [auth 2A],
EL [auth 1A],
ELA [auth 1A],
ELB [auth 1x],
ELC [auth 2A],
EM [auth 1A],
EMA [auth 1A],
EMB [auth 2A],
EMC [auth 2A],
EN [auth 1A],
ENA [auth 1A],
ENB [auth 2A],
ENC [auth 2A],
EO [auth 1A],
EOA [auth 1A],
EOB [auth 2A],
EOC [auth 2A],
EP [auth 1A],
EPA [auth 1A],
EPB [auth 2A],
EPC [auth 2A],
EQ [auth 1A],
EQA [auth 1A],
EQB [auth 2A],
EQC [auth 2A],
ER [auth 1A],
ERA [auth 1A],
ERB [auth 2A],
ERC [auth 2A],
ES [auth 1A],
ESA [auth 1A],
ESB [auth 2A],
ESC [auth 2A],
ET [auth 1A],
ETA [auth 1A],
ETB [auth 2A],
ETC [auth 2A],
EU [auth 1A],
EUA [auth 1B],
EUB [auth 2A],
EUC [auth 2D],
EV [auth 1A],
EVA [auth 1B],
EVB [auth 2A],
EVC [auth 2F],
EW [auth 1A],
EWA [auth 1E],
EWB [auth 2A],
EWC [auth 25],
EX [auth 1A],
EXA [auth 1N],
EXB [auth 2A],
EXC [auth 2a],
EY [auth 1A],
EYA [auth 1S],
EYB [auth 2A],
EYC [auth 2a],
EZ [auth 1A],
EZA [auth 1W],
EZB [auth 2A],
EZC [auth 2a],
FAA [auth 1A],
FAB [auth 11],
FAC [auth 2A],
FAD [auth 2a],
FBA [auth 1A],
FBB [auth 17],
FBC [auth 2A],
FBD [auth 2a],
FCA [auth 1A],
FCB [auth 1a],
FCC [auth 2A],
FCD [auth 2a],
FDA [auth 1A],
FDB [auth 1a],
FDC [auth 2A],
FDD [auth 2a],
FE [auth 1A],
FEA [auth 1A],
FEB [auth 1a],
FEC [auth 2A],
FED [auth 2a],
FF [auth 1A],
FFA [auth 1A],
FFB [auth 1a],
FFC [auth 2A],
FFD [auth 2a],
FG [auth 1A],
FGA [auth 1A],
FGB [auth 1a],
FGC [auth 2A],
FGD [auth 2f],
FH [auth 1A],
FHA [auth 1A],
FHB [auth 1a],
FHC [auth 2A],
FHD [auth 2w],
FI [auth 1A],
FIA [auth 1A],
FIB [auth 1a],
FIC [auth 2A],
FJ [auth 1A],
FJA [auth 1A],
FJB [auth 1a],
FJC [auth 2A],
FK [auth 1A],
FKA [auth 1A],
FKB [auth 1h],
FKC [auth 2A],
FL [auth 1A],
FLA [auth 1A],
FLB [auth 1x],
FLC [auth 2A],
FM [auth 1A],
FMA [auth 1A],
FMB [auth 2A],
FMC [auth 2A],
FN [auth 1A],
FNA [auth 1A],
FNB [auth 2A],
FNC [auth 2A],
FO [auth 1A],
FOA [auth 1A],
FOB [auth 2A],
FOC [auth 2A],
FP [auth 1A],
FPA [auth 1A],
FPB [auth 2A],
FPC [auth 2A],
FQ [auth 1A],
FQA [auth 1A],
FQB [auth 2A],
FQC [auth 2A],
FR [auth 1A],
FRA [auth 1A],
FRB [auth 2A],
FRC [auth 2A],
FS [auth 1A],
FSA [auth 1A],
FSB [auth 2A],
FSC [auth 2A],
FT [auth 1A],
FTA [auth 1A],
FTB [auth 2A],
FTC [auth 2A],
FU [auth 1A],
FUA [auth 1B],
FUB [auth 2A],
FUC [auth 2D],
FV [auth 1A],
FVA [auth 1B],
FVB [auth 2A],
FVC [auth 2G],
FW [auth 1A],
FWA [auth 1E],
FWB [auth 2A],
FWC [auth 25],
FX [auth 1A],
FXA [auth 1N],
FXB [auth 2A],
FXC [auth 2a],
FY [auth 1A],
FYA [auth 1S],
FYB [auth 2A],
FYC [auth 2a],
FZ [auth 1A],
FZA [auth 1W],
FZB [auth 2A],
FZC [auth 2a],
GAA [auth 1A],
GAB [auth 11],
GAC [auth 2A],
GAD [auth 2a],
GBA [auth 1A],
GBB [auth 17],
GBC [auth 2A],
GBD [auth 2a],
GCA [auth 1A],
GCB [auth 1a],
GCC [auth 2A],
GCD [auth 2a],
GDA [auth 1A],
GDB [auth 1a],
GDC [auth 2A],
GDD [auth 2a],
GE [auth 1A],
GEA [auth 1A],
GEB [auth 1a],
GEC [auth 2A],
GED [auth 2a],
GF [auth 1A],
GFA [auth 1A],
GFB [auth 1a],
GFC [auth 2A],
GFD [auth 2a],
GG [auth 1A],
GGA [auth 1A],
GGB [auth 1a],
GGC [auth 2A],
GGD [auth 2f],
GH [auth 1A],
GHA [auth 1A],
GHB [auth 1a],
GHC [auth 2A],
GHD [auth 2w],
GI [auth 1A],
GIA [auth 1A],
GIB [auth 1a],
GIC [auth 2A],
GJ [auth 1A],
GJA [auth 1A],
GJB [auth 1a],
GJC [auth 2A],
GK [auth 1A],
GKA [auth 1A],
GKB [auth 1l],
GKC [auth 2A],
GL [auth 1A],
GLA [auth 1A],
GLB [auth 1x],
GLC [auth 2A],
GM [auth 1A],
GMA [auth 1A],
GMB [auth 2A],
GMC [auth 2A],
GN [auth 1A],
GNA [auth 1A],
GNB [auth 2A],
GNC [auth 2A],
GO [auth 1A],
GOA [auth 1A],
GOB [auth 2A],
GOC [auth 2A],
GP [auth 1A],
GPA [auth 1A],
GPB [auth 2A],
GPC [auth 2A],
GQ [auth 1A],
GQA [auth 1A],
GQB [auth 2A],
GQC [auth 2A],
GR [auth 1A],
GRA [auth 1A],
GRB [auth 2A],
GRC [auth 2A],
GS [auth 1A],
GSA [auth 1A],
GSB [auth 2A],
GSC [auth 2A],
GT [auth 1A],
GTA [auth 1A],
GTB [auth 2A],
GTC [auth 2A],
GU [auth 1A],
GUA [auth 1B],
GUB [auth 2A],
GUC [auth 2D],
GV [auth 1A],
GVA [auth 1B],
GVB [auth 2A],
GVC [auth 2N],
GW [auth 1A],
GWA [auth 1E],
GWB [auth 2A],
GWC [auth 25],
GX [auth 1A],
GXA [auth 1N],
GXB [auth 2A],
GXC [auth 2a],
GY [auth 1A],
GYA [auth 1T],
GYB [auth 2A],
GYC [auth 2a],
GZA [auth 1W],
GZB [auth 2A],
GZC [auth 2a],
HAA [auth 1A],
HAB [auth 11],
HAC [auth 2A],
HAD [auth 2a],
HBA [auth 1A],
HBB [auth 18],
HBC [auth 2A],
HBD [auth 2a],
HCA [auth 1A],
HCB [auth 1a],
HCC [auth 2A],
HCD [auth 2a],
HDA [auth 1A],
HDB [auth 1a],
HDC [auth 2A],
HDD [auth 2a],
HE [auth 1A],
HEA [auth 1A],
HEB [auth 1a],
HEC [auth 2A],
HED [auth 2a],
HF [auth 1A],
HFA [auth 1A],
HFB [auth 1a],
HFC [auth 2A],
HFD [auth 2a],
HG [auth 1A],
HGA [auth 1A],
HGB [auth 1a],
HGC [auth 2A],
HGD [auth 2g],
HH [auth 1A],
HHA [auth 1A],
HHB [auth 1a],
HHC [auth 2A],
HHD [auth 2w],
HI [auth 1A],
HIA [auth 1A],
HIB [auth 1a],
HIC [auth 2A],
HJ [auth 1A],
HJA [auth 1A],
HJB [auth 1a],
HJC [auth 2A],
HK [auth 1A],
HKA [auth 1A],
HKB [auth 1l],
HKC [auth 2A],
HL [auth 1A],
HLA [auth 1A],
HLB [auth 1x],
HLC [auth 2A],
HM [auth 1A],
HMA [auth 1A],
HMB [auth 2A],
HMC [auth 2A],
HN [auth 1A],
HNA [auth 1A],
HNB [auth 2A],
HNC [auth 2A],
HO [auth 1A],
HOA [auth 1A],
HOB [auth 2A],
HOC [auth 2A],
HP [auth 1A],
HPA [auth 1A],
HPB [auth 2A],
HPC [auth 2A],
HQ [auth 1A],
HQA [auth 1A],
HQB [auth 2A],
HQC [auth 2A],
HR [auth 1A],
HRA [auth 1A],
HRB [auth 2A],
HRC [auth 2A],
HS [auth 1A],
HSA [auth 1A],
HSB [auth 2A],
HSC [auth 2A],
HT [auth 1A],
HTA [auth 1A],
HTB [auth 2A],
HTC [auth 2A],
HU [auth 1A],
HUA [auth 1B],
HUB [auth 2A],
HUC [auth 2D],
HV [auth 1A],
HVA [auth 1B],
HVB [auth 2A],
HVC [auth 2O],
HW [auth 1A],
HWA [auth 1E],
HWB [auth 2A],
HWC [auth 25],
HX [auth 1A],
HXA [auth 1N],
HXB [auth 2A],
HXC [auth 2a],
HY [auth 1A],
HYA [auth 1T],
HYB [auth 2A],
HYC [auth 2a],
HZ [auth 1A],
HZA [auth 1W],
HZB [auth 2A],
HZC [auth 2a],
IAA [auth 1A],
IAB [auth 11],
IAC [auth 2A],
IAD [auth 2a],
IBA [auth 1A],
IBB [auth 18],
IBC [auth 2A],
IBD [auth 2a],
ICA [auth 1A],
ICB [auth 1a],
ICC [auth 2A],
ICD [auth 2a],
IDA [auth 1A],
IDB [auth 1a],
IDC [auth 2A],
IDD [auth 2a],
IE [auth 1A],
IEA [auth 1A],
IEB [auth 1a],
IEC [auth 2A],
IED [auth 2a],
IF [auth 1A],
IFA [auth 1A],
IFB [auth 1a],
IFC [auth 2A],
IFD [auth 2a],
IG [auth 1A],
IGA [auth 1A],
IGB [auth 1a],
IGC [auth 2A],
IGD [auth 2i],
IH [auth 1A],
IHA [auth 1A],
IHB [auth 1a],
IHC [auth 2A],
IHD [auth 2w],
II [auth 1A],
IIA [auth 1A],
IIB [auth 1a],
IIC [auth 2A],
IJ [auth 1A],
IJA [auth 1A],
IJB [auth 1a],
IJC [auth 2A],
IK [auth 1A],
IKA [auth 1A],
IKB [auth 1m],
IKC [auth 2A],
IL [auth 1A],
ILA [auth 1A],
ILB [auth 1x],
ILC [auth 2A],
IM [auth 1A],
IMA [auth 1A],
IMB [auth 2A],
IMC [auth 2A],
IN [auth 1A],
INA [auth 1A],
INB [auth 2A],
INC [auth 2A],
IO [auth 1A],
IOA [auth 1A],
IOB [auth 2A],
IOC [auth 2A],
IP [auth 1A],
IPA [auth 1A],
IPB [auth 2A],
IPC [auth 2A],
IQ [auth 1A],
IQA [auth 1A],
IQB [auth 2A],
IQC [auth 2A],
IR [auth 1A],
IRA [auth 1A],
IRB [auth 2A],
IRC [auth 2A],
IS [auth 1A],
ISA [auth 1A],
ISB [auth 2A],
ISC [auth 2A],
IT [auth 1A],
ITA [auth 1A],
ITB [auth 2A],
ITC [auth 2A],
IU [auth 1A],
IUA [auth 1B],
IUB [auth 2A],
IUC [auth 2D],
IV [auth 1A],
IVA [auth 1B],
IVB [auth 2A],
IVC [auth 2Q],
IW [auth 1A],
IWA [auth 1E],
IWB [auth 2A],
IX [auth 1A],
IXA [auth 1N],
IXB [auth 2A],
IXC [auth 2a],
IY [auth 1A],
IYA [auth 1T],
IYB [auth 2A],
IYC [auth 2a],
IZ [auth 1A],
IZA [auth 1W],
IZB [auth 2A],
IZC [auth 2a],
JAA [auth 1A],
JAB [auth 11],
JAC [auth 2A],
JAD [auth 2a],
JBA [auth 1A],
JBB [auth 18],
JBC [auth 2A],
JBD [auth 2a],
JCA [auth 1A],
JCB [auth 1a],
JCC [auth 2A],
JCD [auth 2a],
JDA [auth 1A],
JDB [auth 1a],
JDC [auth 2A],
JDD [auth 2a],
JE [auth 1A],
JEA [auth 1A],
JEB [auth 1a],
JEC [auth 2A],
JED [auth 2a],
JF [auth 1A],
JFA [auth 1A],
JFB [auth 1a],
JFC [auth 2A],
JFD [auth 2a],
JG [auth 1A],
JGA [auth 1A],
JGB [auth 1a],
JGC [auth 2A],
JGD [auth 2j],
JH [auth 1A],
JHA [auth 1A],
JHB [auth 1a],
JHC [auth 2A],
JHD [auth 2w],
JI [auth 1A],
JIA [auth 1A],
JIB [auth 1a],
JIC [auth 2A],
JJ [auth 1A],
JJA [auth 1A],
JJB [auth 1a],
JJC [auth 2A],
JK [auth 1A],
JKA [auth 1A],
JKB [auth 1n],
JKC [auth 2A],
JL [auth 1A],
JLA [auth 1A],
JLB [auth 1x],
JLC [auth 2A],
JM [auth 1A],
JMA [auth 1A],
JMB [auth 2A],
JMC [auth 2A],
JN [auth 1A],
JNA [auth 1A],
JNB [auth 2A],
JNC [auth 2A],
JO [auth 1A],
JOA [auth 1A],
JOB [auth 2A],
JOC [auth 2A],
JP [auth 1A],
JPA [auth 1A],
JPB [auth 2A],
JPC [auth 2A],
JQ [auth 1A],
JQA [auth 1A],
JQB [auth 2A],
JQC [auth 2A],
JR [auth 1A],
JRA [auth 1A],
JRB [auth 2A],
JRC [auth 2A],
JS [auth 1A],
JSA [auth 1A],
JSB [auth 2A],
JSC [auth 2A],
JT [auth 1A],
JTA [auth 1A],
JTB [auth 2A],
JTC [auth 2A],
JU [auth 1A],
JUA [auth 1B],
JUB [auth 2A],
JUC [auth 2D],
JV [auth 1A],
JVA [auth 1D],
JVB [auth 2A],
JVC [auth 2Q],
JW [auth 1A],
JWA [auth 1F],
JWB [auth 2A],
JWC [auth 26],
JX [auth 1A],
JXA [auth 1O],
JXB [auth 2A],
JXC [auth 2a],
JY [auth 1A],
JYA [auth 1U],
JYB [auth 2A],
JYC [auth 2a],
JZ [auth 1A],
JZA [auth 1X],
JZB [auth 2A],
JZC [auth 2a],
KAA [auth 1A],
KAB [auth 11],
KAC [auth 2A],
KAD [auth 2a],
KBA [auth 1A],
KBB [auth 18],
KBC [auth 2A],
KBD [auth 2a],
KCA [auth 1A],
KCB [auth 1a],
KCC [auth 2A],
KCD [auth 2a],
KD [auth 1A],
KDA [auth 1A],
KDB [auth 1a],
KDC [auth 2A],
KDD [auth 2a],
KE [auth 1A],
KEA [auth 1A],
KEB [auth 1a],
KEC [auth 2A],
KED [auth 2a],
KF [auth 1A],
KFA [auth 1A],
KFB [auth 1a],
KFC [auth 2A],
KFD [auth 2a],
KG [auth 1A],
KGA [auth 1A],
KGB [auth 1a],
KGC [auth 2A],
KGD [auth 2l],
KH [auth 1A],
KHA [auth 1A],
KHB [auth 1a],
KHC [auth 2A],
KI [auth 1A],
KIA [auth 1A],
KIB [auth 1a],
KIC [auth 2A],
KJ [auth 1A],
KJA [auth 1A],
KJB [auth 1a],
KJC [auth 2A],
KK [auth 1A],
KKA [auth 1A],
KKC [auth 2A],
KL [auth 1A],
KLA [auth 1A],
KLB [auth 1x],
KLC [auth 2A],
KM [auth 1A],
KMA [auth 1A],
KMB [auth 2A],
KMC [auth 2A],
KN [auth 1A],
KNA [auth 1A],
KNB [auth 2A],
KNC [auth 2A],
KO [auth 1A],
KOA [auth 1A],
KOB [auth 2A],
KOC [auth 2A],
KP [auth 1A],
KPA [auth 1A],
KPB [auth 2A],
KPC [auth 2A],
KQ [auth 1A],
KQA [auth 1A],
KQB [auth 2A],
KQC [auth 2A],
KR [auth 1A],
KRA [auth 1A],
KRB [auth 2A],
KRC [auth 2A],
KS [auth 1A],
KSA [auth 1A],
KSB [auth 2A],
KSC [auth 2A],
KT [auth 1A],
KTA [auth 1A],
KTB [auth 2A],
KTC [auth 2A],
KU [auth 1A],
KUA [auth 1B],
KUB [auth 2A],
KUC [auth 2D],
KV [auth 1A],
KVA [auth 1D],
KVB [auth 2A],
KVC [auth 2Q],
KW [auth 1A],
KWA [auth 1F],
KWB [auth 2A],
KX [auth 1A],
KXA [auth 1O],
KXB [auth 2A],
KXC [auth 2a],
KY [auth 1A],
KYA [auth 1U],
KYB [auth 2A],
KYC [auth 2a],
KZ [auth 1A],
KZA [auth 1X],
KZB [auth 2A],
KZC [auth 2a],
LAA [auth 1A],
LAB [auth 12],
LAC [auth 2A],
LAD [auth 2a],
LBA [auth 1A],
LBB [auth 18],
LBC [auth 2A],
LBD [auth 2a],
LCA [auth 1A],
LCB [auth 1a],
LCC [auth 2A],
LCD [auth 2a],
LD [auth 1A],
LDA [auth 1A],
LDB [auth 1a],
LDC [auth 2A],
LDD [auth 2a],
LE [auth 1A],
LEA [auth 1A],
LEB [auth 1a],
LEC [auth 2A],
LED [auth 2a],
LF [auth 1A],
LFA [auth 1A],
LFB [auth 1a],
LFC [auth 2A],
LFD [auth 2a],
LG [auth 1A],
LGA [auth 1A],
LGB [auth 1a],
LGC [auth 2A],
LGD [auth 2l],
LH [auth 1A],
LHA [auth 1A],
LHB [auth 1a],
LHC [auth 2A],
LHD [auth 2x],
LI [auth 1A],
LIA [auth 1A],
LIB [auth 1a],
LIC [auth 2A],
LJ [auth 1A],
LJA [auth 1A],
LJB [auth 1a],
LJC [auth 2A],
LK [auth 1A],
LKA [auth 1A],
LKB [auth 1p],
LKC [auth 2A],
LL [auth 1A],
LLA [auth 1A],
LLB [auth 1y],
LLC [auth 2A],
LM [auth 1A],
LMA [auth 1A],
LMB [auth 2A],
LMC [auth 2A],
LN [auth 1A],
LNA [auth 1A],
LNB [auth 2A],
LNC [auth 2A],
LO [auth 1A],
LOA [auth 1A],
LOB [auth 2A],
LOC [auth 2A],
LP [auth 1A],
LPA [auth 1A],
LPB [auth 2A],
LPC [auth 2A],
LQ [auth 1A],
LQA [auth 1A],
LQB [auth 2A],
LQC [auth 2A],
LR [auth 1A],
LRA [auth 1A],
LRB [auth 2A],
LRC [auth 2A],
LS [auth 1A],
LSA [auth 1A],
LSB [auth 2A],
LSC [auth 2A],
LT [auth 1A],
LTA [auth 1A],
LTB [auth 2A],
LTC [auth 2B],
LU [auth 1A],
LUA [auth 1B],
LUB [auth 2A],
LUC [auth 2E],
LV [auth 1A],
LVA [auth 1D],
LVB [auth 2A],
LVC [auth 2R],
LW [auth 1A],
LWA [auth 1F],
LWB [auth 2A],
LWC [auth 27],
LX [auth 1A],
LXA [auth 1O],
LXB [auth 2A],
LXC [auth 2a],
LY [auth 1A],
LYA [auth 1U],
LYB [auth 2A],
LYC [auth 2a],
LZ [auth 1A],
LZA [auth 1X],
LZB [auth 2A],
LZC [auth 2a],
MAA [auth 1A],
MAB [auth 12],
MAC [auth 2A],
MAD [auth 2a],
MBA [auth 1A],
MBB [auth 19],
MBC [auth 2A],
MBD [auth 2a],
MCA [auth 1A],
MCB [auth 1a],
MCC [auth 2A],
MCD [auth 2a],
MD [auth 1A],
MDA [auth 1A],
MDB [auth 1a],
MDC [auth 2A],
MDD [auth 2a],
ME [auth 1A],
MEA [auth 1A],
MEB [auth 1a],
MEC [auth 2A],
MED [auth 2a],
MF [auth 1A],
MFA [auth 1A],
MFB [auth 1a],
MFC [auth 2A],
MFD [auth 2a],
MG [auth 1A],
MGA [auth 1A],
MGB [auth 1a],
MGC [auth 2A],
MGD [auth 2l],
MH [auth 1A],
MHA [auth 1A],
MHB [auth 1a],
MHC [auth 2A],
MHD [auth 2x],
MI [auth 1A],
MIA [auth 1A],
MIB [auth 1a],
MIC [auth 2A],
MJ [auth 1A],
MJA [auth 1A],
MJB [auth 1a],
MJC [auth 2A],
MK [auth 1A],
MKA [auth 1A],
MKB [auth 1s],
MKC [auth 2A],
ML [auth 1A],
MLA [auth 1A],
MLB [auth 2A],
MLC [auth 2A],
MM [auth 1A],
MMA [auth 1A],
MMB [auth 2A],
MMC [auth 2A],
MN [auth 1A],
MNA [auth 1A],
MNB [auth 2A],
MNC [auth 2A],
MO [auth 1A],
MOA [auth 1A],
MOB [auth 2A],
MOC [auth 2A],
MP [auth 1A],
MPA [auth 1A],
MPB [auth 2A],
MPC [auth 2A],
MQ [auth 1A],
MQA [auth 1A],
MQB [auth 2A],
MQC [auth 2A],
MR [auth 1A],
MRA [auth 1A],
MRB [auth 2A],
MRC [auth 2A],
MS [auth 1A],
MSA [auth 1A],
MSB [auth 2A],
MSC [auth 2A],
MT [auth 1A],
MTA [auth 1A],
MTB [auth 2A],
MTC [auth 2B],
MU [auth 1A],
MUA [auth 1B],
MUB [auth 2A],
MUC [auth 2E],
MV [auth 1A],
MVA [auth 1D],
MVB [auth 2A],
MVC [auth 2R],
MW [auth 1A],
MWA [auth 1F],
MWB [auth 2A],
MWC [auth 27],
MX [auth 1A],
MXA [auth 1O],
MXB [auth 2A],
MXC [auth 2a],
MY [auth 1A],
MYA [auth 1U],
MYB [auth 2A],
MYC [auth 2a],
MZ [auth 1A],
MZA [auth 1X],
MZB [auth 2A],
MZC [auth 2a],
NAA [auth 1A],
NAB [auth 13],
NAC [auth 2A],
NAD [auth 2a],
NBA [auth 1A],
NBC [auth 2A],
NBD [auth 2a],
NCA [auth 1A],
NCB [auth 1a],
NCC [auth 2A],
NCD [auth 2a],
ND [auth 1A],
NDA [auth 1A],
NDB [auth 1a],
NDC [auth 2A],
NDD [auth 2a],
NE [auth 1A],
NEA [auth 1A],
NEB [auth 1a],
NEC [auth 2A],
NED [auth 2a],
NF [auth 1A],
NFA [auth 1A],
NFB [auth 1a],
NFC [auth 2A],
NFD [auth 2a],
NG [auth 1A],
NGA [auth 1A],
NGB [auth 1a],
NGC [auth 2A],
NGD [auth 2l],
NH [auth 1A],
NHA [auth 1A],
NHB [auth 1a],
NHC [auth 2A],
NHD [auth 2x],
NI [auth 1A],
NIA [auth 1A],
NIB [auth 1a],
NIC [auth 2A],
NJ [auth 1A],
NJA [auth 1A],
NJB [auth 1a],
NJC [auth 2A],
NK [auth 1A],
NKA [auth 1A],
NKB [auth 1t],
NKC [auth 2A],
NL [auth 1A],
NLA [auth 1A],
NLB [auth 2A],
NLC [auth 2A],
NM [auth 1A],
NMA [auth 1A],
NMB [auth 2A],
NMC [auth 2A],
NN [auth 1A],
NNA [auth 1A],
NNB [auth 2A],
NNC [auth 2A],
NO [auth 1A],
NOA [auth 1A],
NOB [auth 2A],
NOC [auth 2A],
NP [auth 1A],
NPA [auth 1A],
NPB [auth 2A],
NPC [auth 2A],
NQ [auth 1A],
NQA [auth 1A],
NQB [auth 2A],
NQC [auth 2A],
NR [auth 1A],
NRA [auth 1A],
NRB [auth 2A],
NRC [auth 2A],
NS [auth 1A],
NSA [auth 1A],
NSB [auth 2A],
NSC [auth 2A],
NT [auth 1A],
NTA [auth 1A],
NTB [auth 2A],
NTC [auth 2B],
NU [auth 1A],
NUA [auth 1B],
NUB [auth 2A],
NUC [auth 2E],
NV [auth 1A],
NVA [auth 1D],
NVB [auth 2A],
NVC [auth 2R],
NW [auth 1A],
NWA [auth 1F],
NWB [auth 2A],
NWC [auth 27],
NX [auth 1A],
NXA [auth 1O],
NXB [auth 2A],
NXC [auth 2a],
NY [auth 1A],
NYA [auth 1U],
NYB [auth 2A],
NYC [auth 2a],
NZ [auth 1A],
NZA [auth 1X],
NZB [auth 2A],
NZC [auth 2a],
OAA [auth 1A],
OAB [auth 13],
OAC [auth 2A],
OAD [auth 2a],
OBA [auth 1A],
OBB [auth 1a],
OBC [auth 2A],
OBD [auth 2a],
OCA [auth 1A],
OCB [auth 1a],
OCC [auth 2A],
OCD [auth 2a],
OD [auth 1A],
ODA [auth 1A],
ODB [auth 1a],
ODC [auth 2A],
ODD [auth 2a],
OE [auth 1A],
OEA [auth 1A],
OEB [auth 1a],
OEC [auth 2A],
OED [auth 2a],
OF [auth 1A],
OFA [auth 1A],
OFB [auth 1a],
OFC [auth 2A],
OFD [auth 2a],
OG [auth 1A],
OGA [auth 1A],
OGB [auth 1a],
OGC [auth 2A],
OGD [auth 2l],
OH [auth 1A],
OHA [auth 1A],
OHB [auth 1a],
OHC [auth 2A],
OHD [auth 2x],
OI [auth 1A],
OIA [auth 1A],
OIB [auth 1a],
OIC [auth 2A],
OJ [auth 1A],
OJA [auth 1A],
OJB [auth 1a],
OJC [auth 2A],
OK [auth 1A],
OKA [auth 1A],
OKB [auth 1v],
OKC [auth 2A],
OL [auth 1A],
OLA [auth 1A],
OLB [auth 2A],
OLC [auth 2A],
OM [auth 1A],
OMA [auth 1A],
OMB [auth 2A],
OMC [auth 2A],
ON [auth 1A],
ONA [auth 1A],
ONB [auth 2A],
ONC [auth 2A],
OO [auth 1A],
OOA [auth 1A],
OOB [auth 2A],
OOC [auth 2A],
OP [auth 1A],
OPA [auth 1A],
OPB [auth 2A],
OPC [auth 2A],
OQ [auth 1A],
OQA [auth 1A],
OQB [auth 2A],
OQC [auth 2A],
OR [auth 1A],
ORA [auth 1A],
ORB [auth 2A],
ORC [auth 2A],
OS [auth 1A],
OSA [auth 1A],
OSB [auth 2A],
OSC [auth 2A],
OT [auth 1A],
OTA [auth 1A],
OTB [auth 2A],
OTC [auth 2B],
OU [auth 1A],
OUA [auth 1B],
OUB [auth 2A],
OUC [auth 2E],
OV [auth 1A],
OVA [auth 1D],
OVB [auth 2A],
OVC [auth 2S],
OW [auth 1A],
OWA [auth 1F],
OWB [auth 2A],
OWC [auth 28],
OX [auth 1A],
OXA [auth 1P],
OXB [auth 2A],
OXC [auth 2a],
OY [auth 1A],
OYA [auth 1U],
OYB [auth 2A],
OYC [auth 2a],
OZ [auth 1A],
OZA [auth 1X],
OZB [auth 2A],
OZC [auth 2a],
PAA [auth 1A],
PAB [auth 13],
PAC [auth 2A],
PAD [auth 2a],
PBA [auth 1A],
PBB [auth 1a],
PBC [auth 2A],
PBD [auth 2a],
PCA [auth 1A],
PCB [auth 1a],
PCC [auth 2A],
PCD [auth 2a],
PD [auth 1A],
PDA [auth 1A],
PDB [auth 1a],
PDC [auth 2A],
PDD [auth 2a],
PE [auth 1A],
PEA [auth 1A],
PEB [auth 1a],
PEC [auth 2A],
PED [auth 2a],
PF [auth 1A],
PFA [auth 1A],
PFB [auth 1a],
PFC [auth 2A],
PFD [auth 2a],
PG [auth 1A],
PGA [auth 1A],
PGB [auth 1a],
PGC [auth 2A],
PH [auth 1A],
PHA [auth 1A],
PHB [auth 1a],
PHC [auth 2A],
PHD [auth 2x],
PI [auth 1A],
PIA [auth 1A],
PIB [auth 1a],
PIC [auth 2A],
PJ [auth 1A],
PJA [auth 1A],
PJB [auth 1a],
PJC [auth 2A],
PK [auth 1A],
PKA [auth 1A],
PKB [auth 1v],
PKC [auth 2A],
PL [auth 1A],
PLA [auth 1A],
PLB [auth 2A],
PLC [auth 2A],
PM [auth 1A],
PMA [auth 1A],
PMB [auth 2A],
PMC [auth 2A],
PN [auth 1A],
PNA [auth 1A],
PNB [auth 2A],
PNC [auth 2A],
PO [auth 1A],
POA [auth 1A],
POB [auth 2A],
POC [auth 2A],
PP [auth 1A],
PPA [auth 1A],
PPB [auth 2A],
PPC [auth 2A],
PQ [auth 1A],
PQA [auth 1A],
PQB [auth 2A],
PQC [auth 2A],
PR [auth 1A],
PRA [auth 1A],
PRB [auth 2A],
PRC [auth 2A],
PS [auth 1A],
PSA [auth 1A],
PSB [auth 2A],
PSC [auth 2A],
PT [auth 1A],
PTA [auth 1A],
PTB [auth 2A],
PTC [auth 2B],
PU [auth 1A],
PUA [auth 1B],
PUB [auth 2A],
PUC [auth 2E],
PV [auth 1A],
PVA [auth 1D],
PVB [auth 2A],
PVC [auth 2T],
PW [auth 1A],
PWA [auth 1F],
PWB [auth 2A],
PWC [auth 28],
PX [auth 1A],
PXA [auth 1P],
PXB [auth 2A],
PXC [auth 2a],
PY [auth 1A],
PYA [auth 1U],
PYB [auth 2A],
PYC [auth 2a],
PZ [auth 1A],
PZA [auth 1Y],
PZB [auth 2A],
PZC [auth 2a],
QAA [auth 1A],
QAC [auth 2A],
QAD [auth 2a],
QBA [auth 1A],
QBB [auth 1a],
QBC [auth 2A],
QBD [auth 2a],
QCA [auth 1A],
QCB [auth 1a],
QCC [auth 2A],
QCD [auth 2a],
QD [auth 1A],
QDA [auth 1A],
QDB [auth 1a],
QDC [auth 2A],
QDD [auth 2a],
QE [auth 1A],
QEA [auth 1A],
QEB [auth 1a],
QEC [auth 2A],
QED [auth 2a],
QF [auth 1A],
QFA [auth 1A],
QFB [auth 1a],
QFC [auth 2A],
QFD [auth 2a],
QG [auth 1A],
QGA [auth 1A],
QGB [auth 1a],
QGC [auth 2A],
QGD [auth 2p],
QH [auth 1A],
QHA [auth 1A],
QHB [auth 1a],
QHC [auth 2A],
QHD [auth 2y],
QI [auth 1A],
QIA [auth 1A],
QIB [auth 1a],
QIC [auth 2A],
QJ [auth 1A],
QJA [auth 1A],
QJB [auth 1a],
QJC [auth 2A],
QK [auth 1A],
QKA [auth 1A],
QKB [auth 1w],
QKC [auth 2A],
QL [auth 1A],
QLA [auth 1A],
QLB [auth 2A],
QLC [auth 2A],
QM [auth 1A],
QMA [auth 1A],
QMB [auth 2A],
QMC [auth 2A],
QN [auth 1A],
QNA [auth 1A],
QNB [auth 2A],
QNC [auth 2A],
QO [auth 1A],
QOA [auth 1A],
QOB [auth 2A],
QOC [auth 2A],
QP [auth 1A],
QPA [auth 1A],
QPB [auth 2A],
QPC [auth 2A],
QQ [auth 1A],
QQA [auth 1A],
QQB [auth 2A],
QQC [auth 2A],
QR [auth 1A],
QRA [auth 1A],
QRB [auth 2A],
QRC [auth 2A],
QS [auth 1A],
QSA [auth 1A],
QSB [auth 2A],
QSC [auth 2A],
QT [auth 1A],
QTA [auth 1A],
QTB [auth 2A],
QTC [auth 2B],
QU [auth 1A],
QUA [auth 1B],
QUB [auth 2A],
QUC [auth 2E],
QV [auth 1A],
QVA [auth 1D],
QVB [auth 2A],
QVC [auth 2T],
QW [auth 1A],
QWA [auth 1F],
QWB [auth 2A],
QWC [auth 28],
QX [auth 1A],
QXA [auth 1P],
QXB [auth 2A],
QXC [auth 2a],
QY [auth 1A],
QYA [auth 1U],
QYB [auth 2A],
QYC [auth 2a],
QZ [auth 1A],
QZA [auth 1Y],
QZB [auth 2A],
QZC [auth 2a],
RAA [auth 1A],
RAB [auth 15],
RAC [auth 2A],
RAD [auth 2a],
RBA [auth 1A],
RBB [auth 1a],
RBC [auth 2A],
RBD [auth 2a],
RCA [auth 1A],
RCB [auth 1a],
RCC [auth 2A],
RCD [auth 2a],
RD [auth 1A],
RDA [auth 1A],
RDB [auth 1a],
RDC [auth 2A],
RDD [auth 2a],
RE [auth 1A],
REA [auth 1A],
REB [auth 1a],
REC [auth 2A],
RED [auth 2a],
RF [auth 1A],
RFA [auth 1A],
RFB [auth 1a],
RFC [auth 2A],
RFD [auth 2a],
RG [auth 1A],
RGA [auth 1A],
RGB [auth 1a],
RGC [auth 2A],
RGD [auth 2q],
RH [auth 1A],
RHA [auth 1A],
RHB [auth 1a],
RHC [auth 2A],
RHD [auth 2y],
RI [auth 1A],
RIA [auth 1A],
RIB [auth 1a],
RIC [auth 2A],
RJ [auth 1A],
RJA [auth 1A],
RJB [auth 1a],
RJC [auth 2A],
RK [auth 1A],
RKA [auth 1A],
RKB [auth 1w],
RKC [auth 2A],
RL [auth 1A],
RLA [auth 1A],
RLB [auth 2A],
RLC [auth 2A],
RM [auth 1A],
RMA [auth 1A],
RMB [auth 2A],
RMC [auth 2A],
RN [auth 1A],
RNA [auth 1A],
RNB [auth 2A],
RNC [auth 2A],
RO [auth 1A],
ROA [auth 1A],
ROB [auth 2A],
ROC [auth 2A],
RP [auth 1A],
RPA [auth 1A],
RPB [auth 2A],
RPC [auth 2A],
RQ [auth 1A],
RQA [auth 1A],
RQB [auth 2A],
RQC [auth 2A],
RR [auth 1A],
RRA [auth 1A],
RRB [auth 2A],
RRC [auth 2A],
RS [auth 1A],
RSA [auth 1A],
RSB [auth 2A],
RSC [auth 2A],
RT [auth 1A],
RTA [auth 1A],
RTB [auth 2A],
RTC [auth 2B],
RU [auth 1A],
RUA [auth 1B],
RUB [auth 2A],
RUC [auth 2E],
RV [auth 1A],
RVA [auth 1D],
RVB [auth 2A],
RVC [auth 2T],
RW [auth 1A],
RWA [auth 1F],
RWB [auth 2A],
RWC [auth 28],
RX [auth 1A],
RXA [auth 1P],
RXB [auth 2A],
RXC [auth 2a],
RY [auth 1A],
RYA [auth 1U],
RYB [auth 2A],
RYC [auth 2a],
RZ [auth 1A],
RZA [auth 1Y],
RZB [auth 2A],
RZC [auth 2a],
SAA [auth 1A],
SAB [auth 15],
SAC [auth 2A],
SAD [auth 2a],
SBA [auth 1A],
SBB [auth 1a],
SBC [auth 2A],
SBD [auth 2a],
SCA [auth 1A],
SCB [auth 1a],
SCC [auth 2A],
SCD [auth 2a],
SD [auth 1A],
SDA [auth 1A],
SDB [auth 1a],
SDC [auth 2A],
SDD [auth 2a],
SE [auth 1A],
SEA [auth 1A],
SEB [auth 1a],
SEC [auth 2A],
SED [auth 2a],
SF [auth 1A],
SFA [auth 1A],
SFB [auth 1a],
SFC [auth 2A],
SFD [auth 2a],
SG [auth 1A],
SGA [auth 1A],
SGB [auth 1a],
SGC [auth 2A],
SGD [auth 2q],
SH [auth 1A],
SHA [auth 1A],
SHB [auth 1a],
SHC [auth 2A],
SHD [auth 2y],
SI [auth 1A],
SIA [auth 1A],
SIB [auth 1a],
SIC [auth 2A],
SJ [auth 1A],
SJA [auth 1A],
SJB [auth 1a],
SJC [auth 2A],
SK [auth 1A],
SKA [auth 1A],
SKB [auth 1w],
SKC [auth 2A],
SL [auth 1A],
SLA [auth 1A],
SLB [auth 2A],
SLC [auth 2A],
SM [auth 1A],
SMA [auth 1A],
SMB [auth 2A],
SMC [auth 2A],
SN [auth 1A],
SNA [auth 1A],
SNB [auth 2A],
SNC [auth 2A],
SO [auth 1A],
SOA [auth 1A],
SOB [auth 2A],
SOC [auth 2A],
SP [auth 1A],
SPA [auth 1A],
SPB [auth 2A],
SPC [auth 2A],
SQ [auth 1A],
SQA [auth 1A],
SQB [auth 2A],
SQC [auth 2A],
SR [auth 1A],
SRA [auth 1A],
SRB [auth 2A],
SRC [auth 2A],
SS [auth 1A],
SSA [auth 1A],
SSB [auth 2A],
SSC [auth 2A],
ST [auth 1A],
STA [auth 1A],
STB [auth 2A],
STC [auth 2B],
SU [auth 1A],
SUA [auth 1B],
SUB [auth 2A],
SUC [auth 2E],
SV [auth 1A],
SVA [auth 1D],
SVB [auth 2A],
SVC [auth 2U],
SW [auth 1A],
SWA [auth 1F],
SWB [auth 2A],
SWC [auth 29],
SX [auth 1A],
SXA [auth 1Q],
SXB [auth 2A],
SXC [auth 2a],
SY [auth 1A],
SYA [auth 1U],
SYB [auth 2A],
SYC [auth 2a],
SZ [auth 1A],
SZB [auth 2A],
SZC [auth 2a],
TAA [auth 1A],
TAB [auth 15],
TAC [auth 2A],
TAD [auth 2a],
TBA [auth 1A],
TBB [auth 1a],
TBC [auth 2A],
TBD [auth 2a],
TCA [auth 1A],
TCB [auth 1a],
TCC [auth 2A],
TCD [auth 2a],
TD [auth 1A],
TDA [auth 1A],
TDB [auth 1a],
TDC [auth 2A],
TDD [auth 2a],
TE [auth 1A],
TEA [auth 1A],
TEB [auth 1a],
TEC [auth 2A],
TED [auth 2a],
TF [auth 1A],
TFA [auth 1A],
TFB [auth 1a],
TFC [auth 2A],
TFD [auth 2a],
TG [auth 1A],
TGA [auth 1A],
TGB [auth 1a],
TGC [auth 2A],
TGD [auth 2r],
TH [auth 1A],
THA [auth 1A],
THB [auth 1a],
THC [auth 2A],
THD [auth 2y],
TI [auth 1A],
TIA [auth 1A],
TIB [auth 1a],
TIC [auth 2A],
TJ [auth 1A],
TJA [auth 1A],
TJB [auth 1a],
TJC [auth 2A],
TK [auth 1A],
TKA [auth 1A],
TKB [auth 1w],
TKC [auth 2A],
TL [auth 1A],
TLA [auth 1A],
TLB [auth 2A],
TLC [auth 2A],
TM [auth 1A],
TMA [auth 1A],
TMB [auth 2A],
TMC [auth 2A],
TN [auth 1A],
TNA [auth 1A],
TNB [auth 2A],
TNC [auth 2A],
TO [auth 1A],
TOA [auth 1A],
TOB [auth 2A],
TOC [auth 2A],
TP [auth 1A],
TPA [auth 1A],
TPB [auth 2A],
TPC [auth 2A],
TQ [auth 1A],
TQA [auth 1A],
TQB [auth 2A],
TQC [auth 2A],
TR [auth 1A],
TRA [auth 1A],
TRB [auth 2A],
TRC [auth 2A],
TS [auth 1A],
TSA [auth 1A],
TSB [auth 2A],
TSC [auth 2A],
TT [auth 1A],
TTA [auth 1A],
TTB [auth 2A],
TTC [auth 2B],
TU [auth 1A],
TUA [auth 1B],
TUB [auth 2A],
TUC [auth 2E],
TV [auth 1A],
TVA [auth 1D],
TVB [auth 2A],
TVC [auth 2U],
TW [auth 1A],
TWA [auth 1F],
TWB [auth 2A],
TX [auth 1A],
TXA [auth 1Q],
TXB [auth 2A],
TXC [auth 2a],
TY [auth 1A],
TYA [auth 1U],
TYB [auth 2A],
TYC [auth 2a],
TZ [auth 1A],
TZA [auth 1Z],
TZB [auth 2A],
TZC [auth 2a],
UAA [auth 1A],
UAB [auth 15],
UAC [auth 2A],
UAD [auth 2a],
UBA [auth 1A],
UBB [auth 1a],
UBC [auth 2A],
UBD [auth 2a],
UCA [auth 1A],
UCB [auth 1a],
UCC [auth 2A],
UCD [auth 2a],
UD [auth 1A],
UDA [auth 1A],
UDB [auth 1a],
UDC [auth 2A],
UDD [auth 2a],
UE [auth 1A],
UEA [auth 1A],
UEB [auth 1a],
UEC [auth 2A],
UED [auth 2a],
UF [auth 1A],
UFA [auth 1A],
UFB [auth 1a],
UFC [auth 2A],
UFD [auth 2a],
UG [auth 1A],
UGA [auth 1A],
UGB [auth 1a],
UGC [auth 2A],
UGD [auth 2t],
UH [auth 1A],
UHA [auth 1A],
UHB [auth 1a],
UHC [auth 2A],
UHD [auth 2y],
UI [auth 1A],
UIA [auth 1A],
UIB [auth 1a],
UIC [auth 2A],
UJ [auth 1A],
UJA [auth 1A],
UJB [auth 1a],
UJC [auth 2A],
UK [auth 1A],
UKA [auth 1A],
UKB [auth 1w],
UKC [auth 2A],
UL [auth 1A],
ULA [auth 1A],
ULB [auth 2A],
ULC [auth 2A],
UM [auth 1A],
UMA [auth 1A],
UMB [auth 2A],
UMC [auth 2A],
UN [auth 1A],
UNA [auth 1A],
UNB [auth 2A],
UNC [auth 2A],
UO [auth 1A],
UOA [auth 1A],
UOB [auth 2A],
UOC [auth 2A],
UP [auth 1A],
UPA [auth 1A],
UPB [auth 2A],
UPC [auth 2A],
UQ [auth 1A],
UQA [auth 1A],
UQB [auth 2A],
UQC [auth 2A],
UR [auth 1A],
URA [auth 1A],
URB [auth 2A],
URC [auth 2A],
US [auth 1A],
USA [auth 1A],
USB [auth 2A],
USC [auth 2A],
UT [auth 1A],
UTA [auth 1A],
UTB [auth 2A],
UTC [auth 2B],
UU [auth 1A],
UUA [auth 1B],
UUB [auth 2A],
UUC [auth 2E],
UV [auth 1A],
UVA [auth 1D],
UVB [auth 2A],
UVC [auth 2V],
UW [auth 1A],
UWA [auth 1F],
UWB [auth 2A],
UWC [auth 2a],
UX [auth 1A],
UXA [auth 1Q],
UXB [auth 2A],
UXC [auth 2a],
UY [auth 1A],
UYA [auth 1V],
UYB [auth 2A],
UYC [auth 2a],
UZ [auth 1A],
UZA [auth 1Z],
UZB [auth 2A],
UZC [auth 2a],
VAA [auth 1A],
VAB [auth 15],
VAC [auth 2A],
VAD [auth 2a],
VBA [auth 1A],
VBB [auth 1a],
VBC [auth 2A],
VBD [auth 2a],
VCA [auth 1A],
VCB [auth 1a],
VCC [auth 2A],
VCD [auth 2a],
VD [auth 1A],
VDA [auth 1A],
VDB [auth 1a],
VDC [auth 2A],
VDD [auth 2a],
VE [auth 1A],
VEA [auth 1A],
VEB [auth 1a],
VEC [auth 2A],
VED [auth 2a],
VF [auth 1A],
VFA [auth 1A],
VFB [auth 1a],
VFC [auth 2A],
VFD [auth 2a],
VG [auth 1A],
VGA [auth 1A],
VGB [auth 1a],
VGC [auth 2A],
VGD [auth 2v],
VH [auth 1A],
VHA [auth 1A],
VHB [auth 1a],
VHC [auth 2A],
VHD [auth 2y],
VI [auth 1A],
VIA [auth 1A],
VIB [auth 1a],
VIC [auth 2A],
VJ [auth 1A],
VJA [auth 1A],
VJB [auth 1a],
VJC [auth 2A],
VK [auth 1A],
VKA [auth 1A],
VKB [auth 1w],
VKC [auth 2A],
VL [auth 1A],
VLA [auth 1A],
VLB [auth 2A],
VLC [auth 2A],
VM [auth 1A],
VMA [auth 1A],
VMB [auth 2A],
VMC [auth 2A],
VN [auth 1A],
VNA [auth 1A],
VNB [auth 2A],
VNC [auth 2A],
VO [auth 1A],
VOA [auth 1A],
VOB [auth 2A],
VOC [auth 2A],
VP [auth 1A],
VPA [auth 1A],
VPB [auth 2A],
VPC [auth 2A],
VQ [auth 1A],
VQA [auth 1A],
VQB [auth 2A],
VQC [auth 2A],
VR [auth 1A],
VRA [auth 1A],
VRB [auth 2A],
VRC [auth 2A],
VS [auth 1A],
VSA [auth 1A],
VSB [auth 2A],
VSC [auth 2A],
VT [auth 1A],
VTA [auth 1A],
VTB [auth 2A],
VTC [auth 2B],
VU [auth 1A],
VUA [auth 1B],
VUB [auth 2A],
VUC [auth 2E],
VV [auth 1A],
VVA [auth 1E],
VVB [auth 2A],
VVC [auth 2V],
VW [auth 1A],
VWA [auth 1F],
VWB [auth 2A],
VWC [auth 2a],
VX [auth 1A],
VXA [auth 1Q],
VXB [auth 2A],
VXC [auth 2a],
VY [auth 1A],
VYA [auth 1V],
VYB [auth 2A],
VYC [auth 2a],
VZ [auth 1A],
VZA [auth 1Z],
VZB [auth 2A],
VZC [auth 2a],
WAA [auth 1A],
WAB [auth 15],
WAC [auth 2A],
WAD [auth 2a],
WBA [auth 1A],
WBB [auth 1a],
WBC [auth 2A],
WBD [auth 2a],
WCA [auth 1A],
WCB [auth 1a],
WCC [auth 2A],
WCD [auth 2a],
WD [auth 1A],
WDA [auth 1A],
WDB [auth 1a],
WDC [auth 2A],
WDD [auth 2a],
WE [auth 1A],
WEA [auth 1A],
WEB [auth 1a],
WEC [auth 2A],
WED [auth 2a],
WF [auth 1A],
WFA [auth 1A],
WFB [auth 1a],
WFC [auth 2A],
WFD [auth 2a],
WG [auth 1A],
WGA [auth 1A],
WGB [auth 1a],
WGC [auth 2A],
WGD [auth 2v],
WH [auth 1A],
WHA [auth 1A],
WHB [auth 1a],
WHC [auth 2A],
WI [auth 1A],
WIA [auth 1A],
WIB [auth 1a],
WIC [auth 2A],
WJ [auth 1A],
WJA [auth 1A],
WJB [auth 1a],
WJC [auth 2A],
WK [auth 1A],
WKA [auth 1A],
WKB [auth 1w],
WKC [auth 2A],
WL [auth 1A],
WLA [auth 1A],
WLB [auth 2A],
WLC [auth 2A],
WM [auth 1A],
WMA [auth 1A],
WMB [auth 2A],
WMC [auth 2A],
WN [auth 1A],
WNA [auth 1A],
WNB [auth 2A],
WNC [auth 2A],
WO [auth 1A],
WOA [auth 1A],
WOB [auth 2A],
WOC [auth 2A],
WP [auth 1A],
WPA [auth 1A],
WPB [auth 2A],
WPC [auth 2A],
WQ [auth 1A],
WQA [auth 1A],
WQB [auth 2A],
WQC [auth 2A],
WR [auth 1A],
WRA [auth 1A],
WRB [auth 2A],
WRC [auth 2A],
WS [auth 1A],
WSA [auth 1A],
WSB [auth 2A],
WSC [auth 2A],
WT [auth 1A],
WTA [auth 1A],
WTB [auth 2A],
WTC [auth 2B],
WU [auth 1A],
WUA [auth 1B],
WUB [auth 2A],
WUC [auth 2F],
WV [auth 1A],
WVA [auth 1E],
WVB [auth 2A],
WVC [auth 2W],
WW [auth 1A],
WWA [auth 1G],
WWB [auth 2A],
WWC [auth 2a],
WX [auth 1A],
WXA [auth 1Q],
WXB [auth 2A],
WXC [auth 2a],
WY [auth 1A],
WYA [auth 1V],
WYB [auth 2A],
WYC [auth 2a],
WZ [auth 1A],
WZA [auth 10],
WZB [auth 2A],
WZC [auth 2a],
XAA [auth 1A],
XAB [auth 15],
XAC [auth 2A],
XAD [auth 2a],
XBA [auth 1A],
XBB [auth 1a],
XBC [auth 2A],
XBD [auth 2a],
XCA [auth 1A],
XCB [auth 1a],
XCC [auth 2A],
XCD [auth 2a],
XD [auth 1A],
XDA [auth 1A],
XDB [auth 1a],
XDC [auth 2A],
XDD [auth 2a],
XE [auth 1A],
XEA [auth 1A],
XEB [auth 1a],
XEC [auth 2A],
XED [auth 2a],
XF [auth 1A],
XFA [auth 1A],
XFB [auth 1a],
XFC [auth 2A],
XFD [auth 2a],
XG [auth 1A],
XGA [auth 1A],
XGB [auth 1a],
XGC [auth 2A],
XGD [auth 2v],
XH [auth 1A],
XHA [auth 1A],
XHB [auth 1a],
XHC [auth 2A],
XI [auth 1A],
XIA [auth 1A],
XIB [auth 1a],
XIC [auth 2A],
XJ [auth 1A],
XJA [auth 1A],
XJB [auth 1a],
XJC [auth 2A],
XK [auth 1A],
XKA [auth 1A],
XKB [auth 1w],
XKC [auth 2A],
XL [auth 1A],
XLA [auth 1A],
XLB [auth 2A],
XLC [auth 2A],
XM [auth 1A],
XMA [auth 1A],
XMB [auth 2A],
XMC [auth 2A],
XN [auth 1A],
XNA [auth 1A],
XNB [auth 2A],
XNC [auth 2A],
XO [auth 1A],
XOA [auth 1A],
XOB [auth 2A],
XOC [auth 2A],
XP [auth 1A],
XPA [auth 1A],
XPB [auth 2A],
XPC [auth 2A],
XQ [auth 1A],
XQA [auth 1A],
XQB [auth 2A],
XQC [auth 2A],
XR [auth 1A],
XRA [auth 1A],
XRB [auth 2A],
XRC [auth 2A],
XS [auth 1A],
XSA [auth 1A],
XSB [auth 2A],
XSC [auth 2A],
XT [auth 1A],
XTA [auth 1A],
XTB [auth 2A],
XTC [auth 2B],
XU [auth 1A],
XUA [auth 1B],
XUB [auth 2A],
XUC [auth 2F],
XV [auth 1A],
XVA [auth 1E],
XVB [auth 2A],
XVC [auth 2W],
XW [auth 1A],
XWA [auth 1G],
XWB [auth 2A],
XWC [auth 2a],
XX [auth 1A],
XXA [auth 1Q],
XXB [auth 2A],
XXC [auth 2a],
XY [auth 1A],
XYA [auth 1V],
XYB [auth 2A],
XYC [auth 2a],
XZ [auth 1A],
XZA [auth 10],
XZB [auth 2A],
XZC [auth 2a],
YAA [auth 1A],
YAB [auth 15],
YAC [auth 2A],
YAD [auth 2a],
YBA [auth 1A],
YBB [auth 1a],
YBC [auth 2A],
YBD [auth 2a],
YCA [auth 1A],
YCB [auth 1a],
YCC [auth 2A],
YCD [auth 2a],
YD [auth 1A],
YDA [auth 1A],
YDB [auth 1a],
YDC [auth 2A],
YDD [auth 2a],
YE [auth 1A],
YEA [auth 1A],
YEB [auth 1a],
YEC [auth 2A],
YED [auth 2a],
YF [auth 1A],
YFA [auth 1A],
YFB [auth 1a],
YFC [auth 2A],
YFD [auth 2a],
YG [auth 1A],
YGA [auth 1A],
YGB [auth 1a],
YGC [auth 2A],
YGD [auth 2w],
YH [auth 1A],
YHA [auth 1A],
YHB [auth 1a],
YHC [auth 2A],
YI [auth 1A],
YIA [auth 1A],
YIB [auth 1a],
YIC [auth 2A],
YJ [auth 1A],
YJA [auth 1A],
YJB [auth 1b],
YJC [auth 2A],
YK [auth 1A],
YKA [auth 1A],
YKB [auth 1x],
YKC [auth 2A],
YL [auth 1A],
YLA [auth 1A],
YLB [auth 2A],
YLC [auth 2A],
YM [auth 1A],
YMA [auth 1A],
YMB [auth 2A],
YMC [auth 2A],
YN [auth 1A],
YNA [auth 1A],
YNB [auth 2A],
YNC [auth 2A],
YO [auth 1A],
YOA [auth 1A],
YOB [auth 2A],
YOC [auth 2A],
YP [auth 1A],
YPA [auth 1A],
YPB [auth 2A],
YPC [auth 2A],
YQ [auth 1A],
YQA [auth 1A],
YQB [auth 2A],
YQC [auth 2A],
YR [auth 1A],
YRA [auth 1A],
YRB [auth 2A],
YRC [auth 2A],
YS [auth 1A],
YSA [auth 1A],
YSB [auth 2A],
YSC [auth 2A],
YT [auth 1A],
YTA [auth 1B],
YTB [auth 2A],
YTC [auth 2B],
YU [auth 1A],
YUA [auth 1B],
YUB [auth 2A],
YUC [auth 2F],
YV [auth 1A],
YVA [auth 1E],
YVB [auth 2A],
YVC [auth 2X],
YW [auth 1A],
YWA [auth 1G],
YWB [auth 2A],
YWC [auth 2a],
YX [auth 1A],
YXA [auth 1Q],
YXB [auth 2A],
YXC [auth 2a],
YY [auth 1A],
YYA [auth 1V],
YYB [auth 2A],
YYC [auth 2a],
YZ [auth 1A],
YZA [auth 10],
YZB [auth 2A],
YZC [auth 2a],
ZAA [auth 1A],
ZAB [auth 15],
ZAC [auth 2A],
ZAD [auth 2a],
ZBA [auth 1A],
ZBB [auth 1a],
ZBC [auth 2A],
ZBD [auth 2a],
ZCA [auth 1A],
ZCB [auth 1a],
ZCC [auth 2A],
ZCD [auth 2a],
ZD [auth 1A],
ZDA [auth 1A],
ZDB [auth 1a],
ZDC [auth 2A],
ZDD [auth 2a],
ZE [auth 1A],
ZEA [auth 1A],
ZEB [auth 1a],
ZEC [auth 2A],
ZED [auth 2a],
ZF [auth 1A],
ZFA [auth 1A],
ZFB [auth 1a],
ZFC [auth 2A],
ZFD [auth 2a],
ZG [auth 1A],
ZGA [auth 1A],
ZGB [auth 1a],
ZGC [auth 2A],
ZGD [auth 2w],
ZH [auth 1A],
ZHA [auth 1A],
ZHB [auth 1a],
ZHC [auth 2A],
ZI [auth 1A],
ZIA [auth 1A],
ZIB [auth 1a],
ZIC [auth 2A],
ZJ [auth 1A],
ZJA [auth 1A],
ZJB [auth 1d],
ZJC [auth 2A],
ZK [auth 1A],
ZKA [auth 1A],
ZKB [auth 1x],
ZKC [auth 2A],
ZL [auth 1A],
ZLA [auth 1A],
ZLB [auth 2A],
ZLC [auth 2A],
ZM [auth 1A],
ZMA [auth 1A],
ZMB [auth 2A],
ZMC [auth 2A],
ZN [auth 1A],
ZNA [auth 1A],
ZNB [auth 2A],
ZNC [auth 2A],
ZO [auth 1A],
ZOA [auth 1A],
ZOB [auth 2A],
ZOC [auth 2A],
ZP [auth 1A],
ZPA [auth 1A],
ZPB [auth 2A],
ZPC [auth 2A],
ZQ [auth 1A],
ZQA [auth 1A],
ZQB [auth 2A],
ZQC [auth 2A],
ZR [auth 1A],
ZRA [auth 1A],
ZRB [auth 2A],
ZRC [auth 2A],
ZS [auth 1A],
ZSA [auth 1A],
ZSB [auth 2A],
ZSC [auth 2A],
ZT [auth 1A],
ZTA [auth 1B],
ZTB [auth 2A],
ZTC [auth 2B],
ZU [auth 1A],
ZUA [auth 1B],
ZUB [auth 2A],
ZUC [auth 2F],
ZV [auth 1A],
ZVA [auth 1E],
ZVB [auth 2A],
ZW [auth 1A],
ZWA [auth 1G],
ZWB [auth 2A],
ZWC [auth 2a],
ZX [auth 1A],
ZXA [auth 1R],
ZXB [auth 2A],
ZXC [auth 2a],
ZY [auth 1A],
ZYA [auth 1V],
ZYB [auth 2A],
ZYC [auth 2a],
ZZ [auth 1A],
ZZA [auth 10],
ZZB [auth 2A],
ZZC [auth 2a]
MAGNESIUM ION
Mg
JLVVSXFLKOJNIY-UHFFFAOYSA-N
Modified Residues  1 Unique
IDChains TypeFormula2D DiagramParent
0TD
Query on 0TD		QA [auth 1l],
VC [auth 2l]		L-PEPTIDE LINKINGC5 H9 N O4 SASP
Experimental Data & Validation

Experimental Data

  • Method: X-RAY DIFFRACTION
  • Resolution: 2.60 Å
  • R-Value Free: 0.266 
  • R-Value Work: 0.215 
  • R-Value Observed: 0.217 
  • Space Group: P 21 21 21
Unit Cell:
Length ( Å )Angle ( ˚ )
a = 210.29α = 90
b = 450.05β = 90
c = 626.34γ = 90
Software Package:
Software NamePurpose
XDSdata reduction
XSCALEdata scaling
PHASERphasing
PHENIXrefinement
Cootmodel building
PDB_EXTRACTdata extraction

Structure Validation

View Full Validation Report



View more in-depth experimental data
Entry History & Funding Information

Deposition Data

Funding OrganizationLocationGrant Number
National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS)United StatesR01-GM132302
National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS)United StatesR35-GM151957
National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS)United StatesR35-GM127134
National Institutes of Health/National Institute Of Allergy and Infectious Diseases (NIH/NIAID)United StatesR01-AI162961
National Science Foundation (NSF, United States)United StatesMCB-2345351
Canadian Institutes of Health Research (CIHR)CanadaPJT190298
Other governmentUniversity of Illinois Startup Funds

Revision History  (Full details and data files)

  • Version 1.0: 2024-11-20
    Type: Initial release