4KAK

Crystal structure of human dihydrofolate reductase complexed with NADPH and 6-ethyl-5-[(3S)-3-[3-methoxy-5-(pyridine-4-yl)phenyl]but-1-yn-1-yl]pyrimidine-2,4-diamine (UCP1006)


Changes made to a PDB entry after its initial release are considered to be either “major” or “minor”. The latest minor version of each major version is available as a file download. More information about the PDB versioning is available.


Version NumberVersion DateVersion Type/Reason Version ChangeRevised CIF Category
1.02013-10-09Initial release
1.12013-10-30Database references
1.22013-11-20Non-polymer description
1.32023-09-20Data collection, Database references, Derived calculations, Refinement descriptionchem_comp_atom, chem_comp_bond, database_2, pdbx_initial_refinement_model, pdbx_struct_conn_angle, struct_conn, struct_site Download