1AGY

The 1.15 angstrom refined structure of fusarium solani pisi cutinase

External Resource: Annotation

Domain Annotation: SCOP/SCOPe Classification
Domain Annotation: SCOP2 Classification
Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification
Structure Motif: Primary M-CSA Annotation

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
A	d1agya_	Alpha and beta proteins (a/b)	alpha/beta-Hydrolases	alpha/beta-Hydrolases	Cutinase-like	Cutinase	(Fusarium vanettenii ) [TaxId: 2747968 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2 Family	Cutinase-like	8031732	4003694	SCOP2 (2022-06-29)
A	SCOP2 Superfamily	alpha/beta-Hydrolases	8044110	3000102	SCOP2 (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	Cutinase	e1agyA1	A: a/b three-layered sandwiches	X: alpha/beta-Hydrolases (From Topology)	H: alpha/beta-Hydrolases (From Topology)	T: alpha/beta-Hydrolases	F: Cutinase	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	3.40.50.1820	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	Alpha/Beta hydrolase fold, catalytic domain	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A	PF01083	Cutinase (Cutinase)	Cutinase	-	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A	CUTINASE	cutinase activity hydrolase activity, acting on ester bonds carboxylic ester hydrolase activity hydrolase activity catalytic activity	-	cellular anatomical structure extracellular region

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A	IPR011150	Cutinase, monofunctional	Family
A	IPR000675	Cutinase/acetylxylan esterase	Family
A	IPR043579	Cutinase, aspartate and histidine active sites	Conserved Site
A	IPR043580	Cutinase, serine active site	Conserved Site
A	IPR029058	Alpha/Beta hydrolase fold	Homologous Superfamily

Structure Motif Annotation: Mechanism and Catalytic Site Atlas M-CSA Database Homepage

Chains	Enzyme Name	Description	Catalytic Residues
A	cutinase M-CSA #631	Cutinase is a serine esterase. It hydrolyses cutin, an insoluble polyester which covers the surface of plants. It is also able to hydrolyse fatty acids esters and emulsified triacylglycerol as efficiently as lipases.	Defined by 5 residues: SER:A-28 [auth A-42]SER:A-106 [auth A-120]GLN:A-107 [auth A-121]ASP:A-161 [auth A-175]HIS:A-174 [auth A-188] \| Explore in 3D: M-CSA Motif Definition Search M-CSA Motif EC: 3.1.1 (PDB Primary Data) Search M-CSA Motif + EC 3.1.1 EC: 3.1.1.74 (UniProt) Search M-CSA Motif + EC 3.1.1.74

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.