Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

ChainsDomain InfoClassFoldSuperfamilyFamilyDomainSpeciesProvenance Source (Version)
Ad1b6sa1 All beta proteins Barrel-sandwich hybrid Rudiment single hybrid motif BC C-terminal domain-like N5-carboxyaminoimidazole ribonucleotide synthetase PurK (AIRC), C-domain (Escherichia coli ) [TaxId: 562 ], SCOPe (2.08)
Ad1b6sa2 Alpha and beta proteins (a/b) PreATP-grasp domain PreATP-grasp domain BC N-terminal domain-like N5-carboxyaminoimidazole ribonucleotide synthetase PurK (AIRC), N-domain (Escherichia coli ) [TaxId: 562 ], SCOPe (2.08)
Ad1b6sa3 Alpha and beta proteins (a+b) ATP-grasp Glutathione synthetase ATP-binding domain-like BC ATP-binding domain-like N5-carboxyaminoimidazole ribonucleotide synthetase PurK (AIRC), domain 2 (Escherichia coli ) [TaxId: 562 ], SCOPe (2.08)
Bd1b6sb1 All beta proteins Barrel-sandwich hybrid Rudiment single hybrid motif BC C-terminal domain-like N5-carboxyaminoimidazole ribonucleotide synthetase PurK (AIRC), C-domain (Escherichia coli ) [TaxId: 562 ], SCOPe (2.08)
Bd1b6sb2 Alpha and beta proteins (a/b) PreATP-grasp domain PreATP-grasp domain BC N-terminal domain-like N5-carboxyaminoimidazole ribonucleotide synthetase PurK (AIRC), N-domain (Escherichia coli ) [TaxId: 562 ], SCOPe (2.08)
Bd1b6sb3 Alpha and beta proteins (a+b) ATP-grasp Glutathione synthetase ATP-binding domain-like BC ATP-binding domain-like N5-carboxyaminoimidazole ribonucleotide synthetase PurK (AIRC), domain 2 (Escherichia coli ) [TaxId: 562 ], SCOPe (2.08)
Cd1b6sc1 All beta proteins Barrel-sandwich hybrid Rudiment single hybrid motif BC C-terminal domain-like N5-carboxyaminoimidazole ribonucleotide synthetase PurK (AIRC), C-domain (Escherichia coli ) [TaxId: 562 ], SCOPe (2.08)
Cd1b6sc2 Alpha and beta proteins (a/b) PreATP-grasp domain PreATP-grasp domain BC N-terminal domain-like N5-carboxyaminoimidazole ribonucleotide synthetase PurK (AIRC), N-domain (Escherichia coli ) [TaxId: 562 ], SCOPe (2.08)
Cd1b6sc3 Alpha and beta proteins (a+b) ATP-grasp Glutathione synthetase ATP-binding domain-like BC ATP-binding domain-like N5-carboxyaminoimidazole ribonucleotide synthetase PurK (AIRC), domain 2 (Escherichia coli ) [TaxId: 562 ], SCOPe (2.08)
Dd1b6sd1 All beta proteins Barrel-sandwich hybrid Rudiment single hybrid motif BC C-terminal domain-like N5-carboxyaminoimidazole ribonucleotide synthetase PurK (AIRC), C-domain (Escherichia coli ) [TaxId: 562 ], SCOPe (2.08)
Dd1b6sd2 Alpha and beta proteins (a/b) PreATP-grasp domain PreATP-grasp domain BC N-terminal domain-like N5-carboxyaminoimidazole ribonucleotide synthetase PurK (AIRC), N-domain (Escherichia coli ) [TaxId: 562 ], SCOPe (2.08)
Dd1b6sd3 Alpha and beta proteins (a+b) ATP-grasp Glutathione synthetase ATP-binding domain-like BC ATP-binding domain-like N5-carboxyaminoimidazole ribonucleotide synthetase PurK (AIRC), domain 2 (Escherichia coli ) [TaxId: 562 ], SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

ChainsTypeFamily Name Domain Identifier Family IdentifierProvenance Source (Version)
ASCOP2B SuperfamilyPreATP-grasp domain 8041114 3001680 SCOP2B (2022-06-29)
ASCOP2B SuperfamilyRudiment single hybrid motif 8041112 3001910 SCOP2B (2022-06-29)
ASCOP2B SuperfamilyGlutathione synthetase ATP-binding domain-like 8041115 3000094 SCOP2B (2022-06-29)
BSCOP2B SuperfamilyPreATP-grasp domain 8041114 3001680 SCOP2B (2022-06-29)
BSCOP2B SuperfamilyRudiment single hybrid motif 8041112 3001910 SCOP2B (2022-06-29)
BSCOP2B SuperfamilyGlutathione synthetase ATP-binding domain-like 8041115 3000094 SCOP2B (2022-06-29)
CSCOP2B SuperfamilyPreATP-grasp domain 8041114 3001680 SCOP2B (2022-06-29)
CSCOP2B SuperfamilyRudiment single hybrid motif 8041112 3001910 SCOP2B (2022-06-29)
CSCOP2B SuperfamilyGlutathione synthetase ATP-binding domain-like 8041115 3000094 SCOP2B (2022-06-29)
DSCOP2B SuperfamilyGlutathione synthetase ATP-binding domain-like 8041115 3000094 SCOP2B (2022-06-29)
DSCOP2B SuperfamilyPreATP-grasp domain 8041114 3001680 SCOP2B (2022-06-29)
DSCOP2B SuperfamilyRudiment single hybrid motif 8041112 3001910 SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

ChainsFamily NameDomain Identifier ArchitecturePossible HomologyHomologyTopologyFamilyProvenance Source (Version)
AATP-graspe1b6sA1 A: a+b complex topologyX: Protein kinase/SAICAR synthase/ATP-grasp (From Homology)H: Protein kinase/SAICAR synthase/ATP-graspT: ATP-graspF: ATP-graspECOD (1.6)
APRK06019_2e1b6sA2 A: a+b complex topologyX: alpha/beta-Hammerhead/Barrel-sandwich hybridH: alpha/beta-Hammerhead/Barrel-sandwich hybridT: CO dehydrogenase molybdoprotein N-domain-likeF: PRK06019_2ECOD (1.6)
A2-Hacid_dh_C_2e1b6sA3 A: a/b three-layered sandwichesX: Rossmann-likeH: Rossmann-relatedT: PreATP-grasp domainF: 2-Hacid_dh_C_2ECOD (1.6)
BATP-graspe1b6sB1 A: a+b complex topologyX: Protein kinase/SAICAR synthase/ATP-grasp (From Homology)H: Protein kinase/SAICAR synthase/ATP-graspT: ATP-graspF: ATP-graspECOD (1.6)
BPRK06019_2e1b6sB2 A: a+b complex topologyX: alpha/beta-Hammerhead/Barrel-sandwich hybridH: alpha/beta-Hammerhead/Barrel-sandwich hybridT: CO dehydrogenase molybdoprotein N-domain-likeF: PRK06019_2ECOD (1.6)
B2-Hacid_dh_C_2e1b6sB3 A: a/b three-layered sandwichesX: Rossmann-likeH: Rossmann-relatedT: PreATP-grasp domainF: 2-Hacid_dh_C_2ECOD (1.6)
CATP-graspe1b6sC1 A: a+b complex topologyX: Protein kinase/SAICAR synthase/ATP-grasp (From Homology)H: Protein kinase/SAICAR synthase/ATP-graspT: ATP-graspF: ATP-graspECOD (1.6)
CPRK06019_2e1b6sC2 A: a+b complex topologyX: alpha/beta-Hammerhead/Barrel-sandwich hybridH: alpha/beta-Hammerhead/Barrel-sandwich hybridT: CO dehydrogenase molybdoprotein N-domain-likeF: PRK06019_2ECOD (1.6)
C2-Hacid_dh_C_2e1b6sC3 A: a/b three-layered sandwichesX: Rossmann-likeH: Rossmann-relatedT: PreATP-grasp domainF: 2-Hacid_dh_C_2ECOD (1.6)
DATP-graspe1b6sD1 A: a+b complex topologyX: Protein kinase/SAICAR synthase/ATP-grasp (From Homology)H: Protein kinase/SAICAR synthase/ATP-graspT: ATP-graspF: ATP-graspECOD (1.6)
DPRK06019_2e1b6sD2 A: a+b complex topologyX: alpha/beta-Hammerhead/Barrel-sandwich hybridH: alpha/beta-Hammerhead/Barrel-sandwich hybridT: CO dehydrogenase molybdoprotein N-domain-likeF: PRK06019_2ECOD (1.6)
D2-Hacid_dh_C_2e1b6sD3 A: a/b three-layered sandwichesX: Rossmann-likeH: Rossmann-relatedT: PreATP-grasp domainF: 2-Hacid_dh_C_2ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Protein Family Annotation Pfam Database Homepage

ChainsAccessionNameDescriptionCommentsSource
A, B, C, D
PF22660Ribonucleotide synthetase preATP-grasp domain (RS_preATP-grasp-like)Ribonucleotide synthetase preATP-grasp domainThis domain precedes the ATP-grasp domain in a number of ribonucleotide synthetases [1-5].Domain
A, B, C, D
PF02222ATP-grasp domain (ATP-grasp)ATP-grasp domain- Family
A, B, C, D
PF17769Phosphoribosylaminoimidazole carboxylase C-terminal domain (PurK_C)Phosphoribosylaminoimidazole carboxylase C-terminal domainThis entry represents the C-terminal domain of the PurK enzyme.Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

ChainsPolymerMolecular FunctionBiological ProcessCellular Component
A, B, C, D
PROTEIN (N5-CARBOXYAMINOIMIDAZOLE RIBONUCLEOTIDE SYNTHETASE)