Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

ChainsDomain InfoClassFoldSuperfamilyFamilyDomainSpeciesProvenance Source (Version)
Ad1f2da1 Alpha and beta proteins (a/b) Tryptophan synthase beta subunit-like PLP-dependent enzymes Tryptophan synthase beta subunit-like PLP-dependent enzymes Tryptophan synthase beta subunit-like PLP-dependent enzymes 1-aminocyclopropane-1-carboxylate deaminase (Cyberlindnera saturnus ) [TaxId: 907340 ], SCOPe (2.08)
Ad1f2da2 Artifacts Tags Tags Tags N-terminal Tags (Cyberlindnera saturnus ) [TaxId: 907340 ], SCOPe (2.08)
Bd1f2db1 Alpha and beta proteins (a/b) Tryptophan synthase beta subunit-like PLP-dependent enzymes Tryptophan synthase beta subunit-like PLP-dependent enzymes Tryptophan synthase beta subunit-like PLP-dependent enzymes 1-aminocyclopropane-1-carboxylate deaminase (Cyberlindnera saturnus ) [TaxId: 907340 ], SCOPe (2.08)
Bd1f2db2 Artifacts Tags Tags Tags N-terminal Tags (Cyberlindnera saturnus ) [TaxId: 907340 ], SCOPe (2.08)
Cd1f2dc1 Alpha and beta proteins (a/b) Tryptophan synthase beta subunit-like PLP-dependent enzymes Tryptophan synthase beta subunit-like PLP-dependent enzymes Tryptophan synthase beta subunit-like PLP-dependent enzymes 1-aminocyclopropane-1-carboxylate deaminase (Cyberlindnera saturnus ) [TaxId: 907340 ], SCOPe (2.08)
Cd1f2dc2 Artifacts Tags Tags Tags N-terminal Tags (Cyberlindnera saturnus ) [TaxId: 907340 ], SCOPe (2.08)
Dd1f2dd1 Alpha and beta proteins (a/b) Tryptophan synthase beta subunit-like PLP-dependent enzymes Tryptophan synthase beta subunit-like PLP-dependent enzymes Tryptophan synthase beta subunit-like PLP-dependent enzymes 1-aminocyclopropane-1-carboxylate deaminase (Cyberlindnera saturnus ) [TaxId: 907340 ], SCOPe (2.08)
Dd1f2dd2 Artifacts Tags Tags Tags N-terminal Tags (Cyberlindnera saturnus ) [TaxId: 907340 ], SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

ChainsTypeFamily Name Domain Identifier Family IdentifierProvenance Source (Version)
ASCOP2 FamilyTryptophan synthase beta subunit-like PLP-dependent enzymes 8020619 4000798 SCOP2 (2022-06-29)
ASCOP2 SuperfamilyTryptophan synthase beta subunit-like PLP-dependent enzymes 8032999 3001427 SCOP2 (2022-06-29)
BSCOP2B SuperfamilyTryptophan synthase beta subunit-like PLP-dependent enzymes 8032999 3001427 SCOP2B (2022-06-29)
CSCOP2B SuperfamilyTryptophan synthase beta subunit-like PLP-dependent enzymes 8032999 3001427 SCOP2B (2022-06-29)
DSCOP2B SuperfamilyTryptophan synthase beta subunit-like PLP-dependent enzymes 8032999 3001427 SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

ChainsFamily NameDomain Identifier ArchitecturePossible HomologyHomologyTopologyFamilyProvenance Source (Version)
APALPe1f2dA1 A: a/b three-layered sandwichesX: Rossmann-likeH: Tryptophan synthase beta subunit-like PLP-dependent enzymes (From Topology)T: Tryptophan synthase beta subunit-like PLP-dependent enzymesF: PALPECOD (1.6)
BPALPe1f2dB1 A: a/b three-layered sandwichesX: Rossmann-likeH: Tryptophan synthase beta subunit-like PLP-dependent enzymes (From Topology)T: Tryptophan synthase beta subunit-like PLP-dependent enzymesF: PALPECOD (1.6)
CPALPe1f2dC2 A: a/b three-layered sandwichesX: Rossmann-likeH: Tryptophan synthase beta subunit-like PLP-dependent enzymes (From Topology)T: Tryptophan synthase beta subunit-like PLP-dependent enzymesF: PALPECOD (1.6)
DPALPe1f2dD1 A: a/b three-layered sandwichesX: Rossmann-likeH: Tryptophan synthase beta subunit-like PLP-dependent enzymes (From Topology)T: Tryptophan synthase beta subunit-like PLP-dependent enzymesF: PALPECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

ChainDomainClassArchitectureTopologyHomologyProvenance Source (Version)
A3.40.50.1100 Alpha Beta 3-Layer(aba) Sandwich Rossmann fold CATH (4.3.0)
B3.40.50.1100 Alpha Beta 3-Layer(aba) Sandwich Rossmann fold CATH (4.3.0)
C3.40.50.1100 Alpha Beta 3-Layer(aba) Sandwich Rossmann fold CATH (4.3.0)
D3.40.50.1100 Alpha Beta 3-Layer(aba) Sandwich Rossmann fold CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

ChainsAccessionNameDescriptionCommentsSource
A, B, C, D
PF00291Pyridoxal-phosphate dependent enzyme (PALP)Pyridoxal-phosphate dependent enzyme- Family

Structure Motif Annotation: Mechanism and Catalytic Site Atlas M-CSA Database Homepage

ChainsEnzyme NameDescriptionCatalytic Residues
1-aminocyclopropane-1-carboxylate deaminase  M-CSA #545

1-aminocyclopropane-1-carboxylate (ACC) deaminase is a pyridoxal phosphate-dependent enzyme which catalyses a cyclopropane ring-opening reaction, the irreversible conversion of ACC to ammonia and alpha-ketobutyrate. In plants, the latter is a precursor of the ripening hormone ethylene. Some plant growth-promoting rhizobacteria can produce 1-aminocyclopropane-1-carboxylate deaminase to enhance plant growth.

ACC deaminase is unique amongst PLP-dependent enzymes, since the ring cleavage catalysed by ACC deaminase cannot proceed through an α-carbanionic intermediate due to the lack of an abstractable alpha-hydrogen atom from the substrate ACC.

Defined by 3 residues: LYS:A-51TYR:A-269TYR:A-295
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