Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

ChainsDomain InfoClassFoldSuperfamilyFamilyDomainSpeciesProvenance Source (Version)
Ad1n4pa_ All alpha proteins alpha-alpha superhelix Protein prenylyltransferase Protein prenylyltransferase Protein farnesyltransferase alpha-subunit Rat (Rattus norvegicus ) [TaxId: 10116 ], SCOPe (2.08)
Cd1n4pc_ All alpha proteins alpha-alpha superhelix Protein prenylyltransferase Protein prenylyltransferase Protein farnesyltransferase alpha-subunit Rat (Rattus norvegicus ) [TaxId: 10116 ], SCOPe (2.08)
Ed1n4pe_ All alpha proteins alpha-alpha superhelix Protein prenylyltransferase Protein prenylyltransferase Protein farnesyltransferase alpha-subunit Rat (Rattus norvegicus ) [TaxId: 10116 ], SCOPe (2.08)
Gd1n4pg_ All alpha proteins alpha-alpha superhelix Protein prenylyltransferase Protein prenylyltransferase Protein farnesyltransferase alpha-subunit Rat (Rattus norvegicus ) [TaxId: 10116 ], SCOPe (2.08)
Id1n4pi_ All alpha proteins alpha-alpha superhelix Protein prenylyltransferase Protein prenylyltransferase Protein farnesyltransferase alpha-subunit Rat (Rattus norvegicus ) [TaxId: 10116 ], SCOPe (2.08)
Kd1n4pk_ All alpha proteins alpha-alpha superhelix Protein prenylyltransferase Protein prenylyltransferase Protein farnesyltransferase alpha-subunit Rat (Rattus norvegicus ) [TaxId: 10116 ], SCOPe (2.08)
Bd1n4pb_ All alpha proteins alpha/alpha toroid Terpenoid cyclases/Protein prenyltransferases Protein prenyltransferases Protein farnesyltransferase, beta-subunit Rat (Rattus norvegicus ) [TaxId: 10116 ], SCOPe (2.08)
Dd1n4pd_ All alpha proteins alpha/alpha toroid Terpenoid cyclases/Protein prenyltransferases Protein prenyltransferases Protein farnesyltransferase, beta-subunit Rat (Rattus norvegicus ) [TaxId: 10116 ], SCOPe (2.08)
Fd1n4pf_ All alpha proteins alpha/alpha toroid Terpenoid cyclases/Protein prenyltransferases Protein prenyltransferases Protein farnesyltransferase, beta-subunit Rat (Rattus norvegicus ) [TaxId: 10116 ], SCOPe (2.08)
Hd1n4ph_ All alpha proteins alpha/alpha toroid Terpenoid cyclases/Protein prenyltransferases Protein prenyltransferases Protein farnesyltransferase, beta-subunit Rat (Rattus norvegicus ) [TaxId: 10116 ], SCOPe (2.08)
Jd1n4pj_ All alpha proteins alpha/alpha toroid Terpenoid cyclases/Protein prenyltransferases Protein prenyltransferases Protein farnesyltransferase, beta-subunit Rat (Rattus norvegicus ) [TaxId: 10116 ], SCOPe (2.08)
Ld1n4pl_ All alpha proteins alpha/alpha toroid Terpenoid cyclases/Protein prenyltransferases Protein prenyltransferases Protein farnesyltransferase, beta-subunit Rat (Rattus norvegicus ) [TaxId: 10116 ], SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

ChainsTypeFamily Name Domain Identifier Family IdentifierProvenance Source (Version)
ASCOP2B SuperfamilyProtein prenylyltransferase 8038634 3001312 SCOP2B (2022-06-29)
CSCOP2B SuperfamilyProtein prenylyltransferase 8038634 3001312 SCOP2B (2022-06-29)
ESCOP2B SuperfamilyProtein prenylyltransferase 8038634 3001312 SCOP2B (2022-06-29)
GSCOP2B SuperfamilyProtein prenylyltransferase 8038634 3001312 SCOP2B (2022-06-29)
ISCOP2B SuperfamilyProtein prenylyltransferase 8038634 3001312 SCOP2B (2022-06-29)
KSCOP2B SuperfamilyProtein prenylyltransferase 8038634 3001312 SCOP2B (2022-06-29)
BSCOP2 FamilyProtein prenyltransferases 8084557 4001193 SCOP2 (2022-06-29)
BSCOP2 SuperfamilyTerpenoid cyclases/Protein prenyltransferases 8084558 3001024 SCOP2 (2022-06-29)
DSCOP2B SuperfamilyTerpenoid cyclases/Protein prenyltransferases 8084558 3001024 SCOP2B (2022-06-29)
FSCOP2B SuperfamilyTerpenoid cyclases/Protein prenyltransferases 8084558 3001024 SCOP2B (2022-06-29)
HSCOP2B SuperfamilyTerpenoid cyclases/Protein prenyltransferases 8084558 3001024 SCOP2B (2022-06-29)
JSCOP2B SuperfamilyTerpenoid cyclases/Protein prenyltransferases 8084558 3001024 SCOP2B (2022-06-29)
LSCOP2B SuperfamilyTerpenoid cyclases/Protein prenyltransferases 8084558 3001024 SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

ChainsFamily NameDomain Identifier ArchitecturePossible HomologyHomologyTopologyFamilyProvenance Source (Version)
APPTAe1n4pA1 A: alpha superhelicesX: Repetitive alpha hairpinsH: ARM repeat (From Topology)T: ARM repeatF: PPTAECOD (1.6)
CPPTAe1n4pC1 A: alpha superhelicesX: Repetitive alpha hairpinsH: ARM repeat (From Topology)T: ARM repeatF: PPTAECOD (1.6)
EPPTAe1n4pE1 A: alpha superhelicesX: Repetitive alpha hairpinsH: ARM repeat (From Topology)T: ARM repeatF: PPTAECOD (1.6)
GPPTAe1n4pG1 A: alpha superhelicesX: Repetitive alpha hairpinsH: ARM repeat (From Topology)T: ARM repeatF: PPTAECOD (1.6)
IPPTAe1n4pI1 A: alpha superhelicesX: Repetitive alpha hairpinsH: ARM repeat (From Topology)T: ARM repeatF: PPTAECOD (1.6)
KPPTAe1n4pK1 A: alpha superhelicesX: Repetitive alpha hairpinsH: ARM repeat (From Topology)T: ARM repeatF: PPTAECOD (1.6)
BSQHop_cyclase_Ce1n4pB1 A: alpha superhelicesX: Repetitive alpha hairpinsH: alpha/alpha toroid (From Topology)T: alpha/alpha toroidF: SQHop_cyclase_CECOD (1.6)
DSQHop_cyclase_Ce1n4pD1 A: alpha superhelicesX: Repetitive alpha hairpinsH: alpha/alpha toroid (From Topology)T: alpha/alpha toroidF: SQHop_cyclase_CECOD (1.6)
FSQHop_cyclase_Ce1n4pF1 A: alpha superhelicesX: Repetitive alpha hairpinsH: alpha/alpha toroid (From Topology)T: alpha/alpha toroidF: SQHop_cyclase_CECOD (1.6)
HSQHop_cyclase_Ce1n4pH1 A: alpha superhelicesX: Repetitive alpha hairpinsH: alpha/alpha toroid (From Topology)T: alpha/alpha toroidF: SQHop_cyclase_CECOD (1.6)
JSQHop_cyclase_Ce1n4pJ1 A: alpha superhelicesX: Repetitive alpha hairpinsH: alpha/alpha toroid (From Topology)T: alpha/alpha toroidF: SQHop_cyclase_CECOD (1.6)
LSQHop_cyclase_Ce1n4pL1 A: alpha superhelicesX: Repetitive alpha hairpinsH: alpha/alpha toroid (From Topology)T: alpha/alpha toroidF: SQHop_cyclase_CECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Protein Family Annotation Pfam Database Homepage

ChainsAccessionNameDescriptionCommentsSource
A, C, E, G, I
PF01239Protein prenyltransferase alpha subunit repeat (PPTA)Protein prenyltransferase alpha subunit repeat- Repeat
B, D, F, H, J
PF00432Prenyltransferase and squalene oxidase repeat (Prenyltrans)Prenyltransferase and squalene oxidase repeat- Repeat

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

ChainsPolymerMolecular FunctionBiological ProcessCellular Component
A, C, E, G, I
Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha
B, D, F, H, J
Geranylgeranyl transferase type-1 subunit beta
M, N
Fusion protein consisting of transforming protein p21b and Ras related protein Rap-2b

Pharos: Disease Associations Pharos Homepage Annotation

ChainsDrug Target  Associated Disease
M, N
PharosP01116