1OI0

CRYSTAL STRUCTURE OF AF2198, A JAB1/MPN DOMAIN PROTEIN FROM ARCHAEOGLOBUS FULGIDUS

External Resource: Annotation

Domain Annotation: SCOP/SCOPe Classification
Domain Annotation: SCOP2 Classification
Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
A	d1oi0a_	Alpha and beta proteins (a/b)	Cytidine deaminase-like	JAB1/MPN domain	JAB1/MPN domain	Hypothetical protein AF2198	(Archaeoglobus fulgidus ) [TaxId: 2234 ],	SCOPe (2.08)
B	d1oi0b_	Alpha and beta proteins (a/b)	Cytidine deaminase-like	JAB1/MPN domain	JAB1/MPN domain	Hypothetical protein AF2198	(Archaeoglobus fulgidus ) [TaxId: 2234 ],	SCOPe (2.08)
C	d1oi0c_	Alpha and beta proteins (a/b)	Cytidine deaminase-like	JAB1/MPN domain	JAB1/MPN domain	Hypothetical protein AF2198	(Archaeoglobus fulgidus ) [TaxId: 2234 ],	SCOPe (2.08)
D	d1oi0d_	Alpha and beta proteins (a/b)	Cytidine deaminase-like	JAB1/MPN domain	JAB1/MPN domain	Hypothetical protein AF2198	(Archaeoglobus fulgidus ) [TaxId: 2234 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2B Superfamily	JAB1/MPN domain-like	8037494	3001105	SCOP2B (2022-06-29)
B	SCOP2B Superfamily	JAB1/MPN domain-like	8037494	3001105	SCOP2B (2022-06-29)
C	SCOP2B Superfamily	JAB1/MPN domain-like	8037494	3001105	SCOP2B (2022-06-29)
D	SCOP2 Family	Prokaryotic JAB domain-like	8025115	4001225	SCOP2 (2022-06-29)
D	SCOP2 Superfamily	JAB1/MPN domain-like	8037494	3001105	SCOP2 (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	Prok-JAB	e1oi0A1	A: a+b three layers	X: Cytidine deaminase-like (From Topology)	H: Cytidine deaminase-like (From Topology)	T: Cytidine deaminase-like	F: Prok-JAB	ECOD (1.6)
B	Prok-JAB	e1oi0B1	A: a+b three layers	X: Cytidine deaminase-like (From Topology)	H: Cytidine deaminase-like (From Topology)	T: Cytidine deaminase-like	F: Prok-JAB	ECOD (1.6)
C	Prok-JAB	e1oi0C1	A: a+b three layers	X: Cytidine deaminase-like (From Topology)	H: Cytidine deaminase-like (From Topology)	T: Cytidine deaminase-like	F: Prok-JAB	ECOD (1.6)
D	Prok-JAB	e1oi0D1	A: a+b three layers	X: Cytidine deaminase-like (From Topology)	H: Cytidine deaminase-like (From Topology)	T: Cytidine deaminase-like	F: Prok-JAB	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	3.40.140.10	Alpha Beta	3-Layer(aba) Sandwich	Cytidine Deaminase	domain 2	CATH (4.3.0)
B	3.40.140.10	Alpha Beta	3-Layer(aba) Sandwich	Cytidine Deaminase	domain 2	CATH (4.3.0)
C	3.40.140.10	Alpha Beta	3-Layer(aba) Sandwich	Cytidine Deaminase	domain 2	CATH (4.3.0)
D	3.40.140.10	Alpha Beta	3-Layer(aba) Sandwich	Cytidine Deaminase	domain 2	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B, C, D	PF14464	Prokaryotic homologs of the JAB domain (Prok-JAB)	Prokaryotic homologs of the JAB domain	-	Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B, C, D	HYPOTHETICAL PROTEIN AF2198	peptidase activity catalytic activity, acting on a protein metallopeptidase activity hydrolase activity catalytic activity cation binding ion binding binding metal ion binding small molecule binding	proteolysis metabolic process cellular process primary metabolic process protein metabolic process macromolecule metabolic process	-

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B, C, D	IPR028090	JAB domain, prokaryotic	Domain
A, B, C, D	IPR037518	MPN domain	Domain

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.