Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

ChainsTypeFamily Name Domain Identifier Family IdentifierProvenance Source (Version)
ASCOP2 FamilyRas-like monodomain GTPases 8060225 4004043 SCOP2 (2022-06-29)
ASCOP2 SuperfamilyRas-like P-loop GTPases 8060226 3002022 SCOP2 (2022-06-29)
BSCOP2B SuperfamilyARM repeat-like 8043374 3000116 SCOP2B (2022-06-29)
CSCOP2B SuperfamilyARM repeat-like 8043375 3000116 SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

ChainsFamily NameDomain Identifier ArchitecturePossible HomologyHomologyTopologyFamilyProvenance Source (Version)
ARase1wa5A1 A: a/b three-layered sandwichesX: P-loop domains-likeH: P-loop domains-relatedT: P-loop containing nucleoside triphosphate hydrolasesF: RasECOD (1.6)
BArme1wa5B1 A: alpha superhelicesX: Repetitive alpha hairpinsH: ARM repeat (From Topology)T: ARM repeatF: ArmECOD (1.6)
CCse1e1wa5C1 A: alpha superhelicesX: Repetitive alpha hairpinsH: ARM repeat (From Topology)T: ARM repeatF: Cse1ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Protein Family Annotation Pfam Database Homepage

ChainsAccessionNameDescriptionCommentsSource
PF00071Ras family (Ras)Ras familyIncludes sub-families Ras, Rab, Rac, Ral, Ran, Rap Ypt1 and more. Shares P-loop motif with GTP_EFTU, arf and myosin_head. See Pfam:PF00009 Pfam:PF00025, Pfam:PF00063. As regards Rab GTPases, these are important regulators of vesicle formation, motil ...Includes sub-families Ras, Rab, Rac, Ral, Ran, Rap Ypt1 and more. Shares P-loop motif with GTP_EFTU, arf and myosin_head. See Pfam:PF00009 Pfam:PF00025, Pfam:PF00063. As regards Rab GTPases, these are important regulators of vesicle formation, motility and fusion. They share a fold in common with all Ras GTPases: this is a six-stranded beta-sheet surrounded by five alpha-helices [1].
Domain
PF00514Armadillo/beta-catenin-like repeat (Arm)Armadillo/beta-catenin-like repeat- Repeat
PF01749Importin beta binding domain (IBB)Importin beta binding domain- Repeat
PF16186Atypical Arm repeat (Arm_3)Atypical Arm repeat- Repeat
PF03378CAS/CSE protein, C-terminus (CAS_CSE1)CAS/CSE protein, C-terminus- Repeat
PF08506Cse1 (Cse1)Cse1- Repeat
PF03810Importin-beta N-terminal domain (IBN_N)Importin-beta N-terminal domain- Repeat

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

ChainsPolymerMolecular FunctionBiological ProcessCellular Component
GTP-binding nuclear protein Ran
SRP1 isoform 1
Importin alpha re-exporter