Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

ChainsDomain InfoClassFoldSuperfamilyFamilyDomainSpeciesProvenance Source (Version)
Ad1yzxa_ Alpha and beta proteins (a/b) Thioredoxin fold Thioredoxin-like DsbA-like automated matches human (Homo sapiens ) [TaxId: 9606 ], SCOPe (2.08)
Bd1yzxb_ Alpha and beta proteins (a/b) Thioredoxin fold Thioredoxin-like DsbA-like automated matches human (Homo sapiens ) [TaxId: 9606 ], SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

ChainsTypeFamily Name Domain Identifier Family IdentifierProvenance Source (Version)
ASCOP2B SuperfamilyThioredoxin-like 8079085 3000031 SCOP2B (2022-06-29)
BSCOP2B SuperfamilyThioredoxin-like 8079085 3000031 SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

ChainsFamily NameDomain Identifier ArchitecturePossible HomologyHomologyTopologyFamilyProvenance Source (Version)
ADSBA_4e1yzxA1 A: alpha arraysX: Insertion subdomain in DsbA-likeH: Insertion subdomain in DsbA-like (From Topology)T: Insertion subdomain in DsbA-likeF: DSBA_4ECOD (1.6)
ADSBA_3e1yzxA2 A: a+b three layersX: Thioredoxin-likeH: Thioredoxin-like (From Topology)T: Thioredoxin-likeF: DSBA_3ECOD (1.6)
BDSBA_4e1yzxB1 A: alpha arraysX: Insertion subdomain in DsbA-likeH: Insertion subdomain in DsbA-like (From Topology)T: Insertion subdomain in DsbA-likeF: DSBA_4ECOD (1.6)
BDSBA_3e1yzxB2 A: a+b three layersX: Thioredoxin-likeH: Thioredoxin-like (From Topology)T: Thioredoxin-likeF: DSBA_3ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

ChainDomainClassArchitectureTopologyHomologyProvenance Source (Version)
A3.40.30.10 Alpha Beta 3-Layer(aba) Sandwich Glutaredoxin GlutaredoxinCATH (4.3.0)
B3.40.30.10 Alpha Beta 3-Layer(aba) Sandwich Glutaredoxin GlutaredoxinCATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

ChainsAccessionNameDescriptionCommentsSource
A, B
PF01323DSBA-like thioredoxin domain (DSBA)DSBA-like thioredoxin domainThis family contains a diverse set of proteins with a thioredoxin-like structure Pfam:PF00085. This family also includes 2-hydroxychromene-2-carboxylate (HCCA) isomerase enzymes catalyse one step in prokaryotic polyaromatic hydrocarbon (PAH) cataboli ...This family contains a diverse set of proteins with a thioredoxin-like structure Pfam:PF00085. This family also includes 2-hydroxychromene-2-carboxylate (HCCA) isomerase enzymes catalyse one step in prokaryotic polyaromatic hydrocarbon (PAH) catabolic pathways [2,3,4]. This family also contains members with functions other than HCCA isomerisation, such as Kappa family GSTs (e.g. Swiss:P24473), whose similarity to HCCA isomerases was not previously recognised. The sequence Swiss:O07298 has been annotated as a dioxygenase but is almost certainly an HCCA isomerase enzyme. Similarly, the sequence Swiss:Q9ZI67 has been annotated as a dehydrogenase, but is most probably also an HCCA isomerase enzyme. In addition, the Rhizobium leguminosarum Swiss:Q52782 protein has been annotated as a putative glycerol-3-phosphate transfer protein, but is also most likely to be an HCCA isomerase enzyme (see [5]).
Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

ChainsPolymerMolecular FunctionBiological ProcessCellular Component
A, B
Glutathione S-transferase kappa 1